Malignant peripheral nerve sheath tumours in the head and neck region: retrospective analysis of clinicopathological features and treatment outcomes

2014 ◽  
Vol 43 (8) ◽  
pp. 924-932 ◽  
Author(s):  
C. Ma ◽  
A. Ow ◽  
O.H. Shan ◽  
Y. Wu ◽  
C. Zhang ◽  
...  
1992 ◽  
Vol 106 (11) ◽  
pp. 1011-1015 ◽  
Author(s):  
Martin J. Donnelly ◽  
Mohammed Hussain Al-Sader ◽  
Alexander W. Blayney

AbstractNerve sheath tumours of the head and neck region mainly involve the eighth cranial nerve with only 4 per cent occurring in the paranasal sinuses. Only 32 cases of benign schwannomas occurring in the paranasal sinuses have been reported. We present a further case, review the current literature, and discuss the clinical details and specific histological features.


2004 ◽  
Vol 118 (2) ◽  
pp. 156-158 ◽  
Author(s):  
Robert Almeyda ◽  
Prasad Kothari ◽  
Ha Chau ◽  
Vincent Cumberworth

Neurilemmomas are slow growing, benign neoplasms of neural crest Schwann cell origin. They arise from any peripheral, spinal or cranial nerve except the olfactory and optic. Presentation is usually asymptomatic but focal neurological signs and symptoms may be associated with nerve compression. With approximately one third of all documented cases presenting in the head and neck region, we report a case of a submandibular neurilemmoma misdiagnosed pre-operatively. The diagnostic difficulties are discussed and the current literature reviewed. Thiscase highlights the importance of inclusion of nerve sheath tumours in differential diagnoses of soft tissue lesions in the head and neck.


2015 ◽  
Vol 22 (07) ◽  
pp. 973-977
Author(s):  
Samuel Seseja ◽  
Jeremiah Moshy

Malignant peripheral nerve sheath tumours (MPNSTs) are rare, aggressive softtissue sarcomas associated with poor prognosis, that most commonly affect patients aged20 to 50 years, but have also been reported in children. The tumour is usually found in lowerextremities and only 10% to 20% of all lesions occur in head and neck region thus making ita rare entity. Central involvement, particularly in the jawbones is quite unusual. There is littlereported in literature on these tumors in Africa. Here we report a rare case of intraosseousMPNSTS occurring in the mandible in a 12-years old girl. The biological behavior and diagnosticchallenges of this rare malignancy are discussed.


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