scholarly journals Spread of anthelmintic resistance in intestinal helminths of dogs and cats is currently less pronounced than in ruminants and horses – Yet it is of major concern

2021 ◽  
Author(s):  
Georg von Samson-Himmelstjerna ◽  
RC Andrew Thompson ◽  
Jürgen Krücken ◽  
Warwick Grant ◽  
Dwight D. Bowman ◽  
...  
Keyword(s):  
Anthelmintic Resistance ◽  
Intestinal Helminths

A study on the intestinal helminths of the patients in a leprosarium in Korea

1983 ◽  
Vol 21 (1) ◽  
pp. 102 ◽  
Author(s):  
Sung Tae Hong ◽  
Sung Jong Hong ◽  
Soon Hyung Lee ◽  
Ik Sang Kim ◽  
Jung Sik Shin
Keyword(s):  
Intestinal Helminths

Gastro-intestinal helminths detected by fecal examination in stray dogs in the Konya province

2014 ◽  
Vol 30 (3) ◽  
pp. 162-162 ◽  
Author(s):  
Nermin Isik ◽  
Özlem Derinbay Ekici ◽  
Serkan İrfan Köse
Keyword(s):  
Intestinal Helminths ◽  
Fecal Examination ◽  
Stray Dogs

Effect of Jatropha curcas Latex on L3 Haemonchus contortus Larval Motility

2017 ◽  
Vol 9 (3) ◽  
Author(s):  
Noorzaid Muhamad ◽  
Syahirah Sazeli ◽  
Resni Mona ◽  
Jannathul Firdous
Keyword(s):  
Larvicidal Activity ◽  
Jatropha Curcas ◽  
Haemonchus Contortus ◽  
Anthelmintic Resistance ◽  
Small Ruminants ◽  
Gastrointestinal Nematodes ◽  
Dose Dependent ◽  
Plants Extract

The anthelmintic resistance has limited the control of gastrointestinal nematodes of small ruminants and thus has awakened interest in the study of plants extract as a source of anthelmintics. These experiments were carried out to evaluate the in vitro efficacy of Jatrophacurcas latex extract against Haemonchuscontortus larval motility. To evaluate the larvicidal activity, H.contortus L3 were incubated with the extracts with varying concentration of 5 mg/mL, 10 mg/mL, 15 mg/mL and 20 mg/mL at 27°C for 48, 72 and 96 hrs. The results were subjected to the Kruskal-Wallis test (P less than 0.05). The extracts showed dose-dependent larvicidal effects. These results suggest that J.curcas can be used to control gastrointestinal nematodes of small ruminants.

Field and Molecular Evaluation of Anthelmintic Resistance of Nematode Populations from Cattle and Sheep Naturally Infected Pastured on Mixed Grazing areas at Rio Grande do Sul, Brazil

2019 ◽  
Vol 65 (1) ◽  
pp. 118-127
Author(s):  
Fernanda Ramos ◽  
Camila Balconi Marques ◽  
Caroline Zamperete Reginato ◽  
Patricia Bräunig ◽  
Vanessa Osmari ◽  
...  
Keyword(s):  
Anthelmintic Resistance ◽  
Rio Grande ◽  
Rio Grande Do Sul ◽  
Molecular Evaluation ◽  
Cattle And Sheep

scholarly journals Comorbidity of Geo-Helminthes among Malaria Outpatients of the Health Facilities in Ethiopia: Systematic Review and Meta-Analysis

2021 ◽  
Vol 18 (3) ◽  
pp. 862
Author(s):  
Minyahil Tadesse Boltena ◽  
Ziad El-Khatib ◽  
Abraham Sahlemichael Kebede ◽  
Benedict Oppong Asamoah ◽  
Andualem Tadesse Boltena ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Protein Energy Malnutrition ◽  
Random Effect ◽  
Plasmodium Species ◽  
Intestinal Helminth ◽  
Parasitic Infections ◽  
Intestinal Helminths ◽  
Soil Transmitted Helminths ◽  
Pooled Prevalence

Background: Coinfection of malaria and intestinal helminths affects one third of the global population, largely among communities with severe poverty. The spread of these parasitic infections overlays in several epidemiological locations and the host shows different outcomes. This systematic review and meta-analysis determine the pooled prevalence of malaria and intestinal helminthiases coinfections among malaria suspected patients in Ethiopia. Methods: Primary studies published in English language were retrieved using appropriate search terms on Google Scholar, PubMed/MEDLINE, CINHAL, Scopus, and Embase. The Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI) was used for critical appraisal of studies. A pooled statistical meta-analysis was conducted using STATA Version 14.0 software. The heterogeneity and publication bias were assessed using the I2 statistics and Egger’s test, respectively. Duval and Tweedie’s nonparametric trim and fill analysis using the random-effect analysis. The Random effects model was used to estimate the summary prevalence of comorbidity of malaria and soil transmitted helminthiases and the corresponding 95% confidence intervals (CI). The review protocol has registered in PROSPERO number CRD42019144803. Results: We identified ten studies (n = 6633 participants) in this study. The overall pooled result showed 13% of the ambulatory patients infected by malaria and intestinal helminths concurrently in Ethiopia. The pooled prevalence of Plasmodium falciparum and Plasmodium vivax, and mixed infections were 12, 30, and 6%, respectively. The most common intestinal helminth parasites detected were Hookworm, Ascaris lumbricoides, and Tirchuris trichiura. Conclusions: The comorbidity of malaria and intestinal helminths causes lower hemoglobin level leading to maternal anemia, preterm delivery, and still birth in pregnant women and lactating mother. School-aged children and neonates coinfected by plasmodium species and soil transmitted helminths develop cognitive impairment, protein energy malnutrition, low birth weight, small for gestational age, and gross motor delay. The Ministry of Health of Ethiopia and its international partners working on malaria elimination programs should give more emphasis to the effect of the interface of malaria and soil transmitted helminths, which calls for an integrated disease control and prevention.

scholarly journals PSV-37 Reemergence of cyathostomins species demonstrates anthelmintic resistance following drug administration in horses

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 335-335
Author(s):  
Alexa C Johnson ◽  
Amy S Biddle
Keyword(s):  
Anthelmintic Resistance ◽  
Macrocyclic Lactones ◽  
Number Of Species ◽  
Molecular Approaches ◽  
Pyrantel Pamoate ◽  
Drug Classes ◽  
Blast Database ◽  
Resistance Patterns ◽  
Near Future ◽  
Ncbi Blast

Abstract Arbitrary administration of anthelmintics to control equine gastrointestinal worms has led to increased resistance to the three broad-spectrum drug classes; benzimidazoles, tetrahydropyrimidines, and macrocyclic lactones. With little promise of new drug classes to target cyathostomins being introduced to the market in the near future, anthelmintic drugs must be administered judiciously to prevent complete anthelmintic parasite resistance. The objective of this study is to determine the reemergence rate of cyathostomins following three commercial horse dewormers during summer. Nine horses housed at two locations were enrolled to the study and was repeated June–September through 2017–2019. Horses were removed from the study if sequencing failed due to low egg recovery for more than 50% of the timepoints. Ivermectin (macrocyclic lactones; n = 6), Moxidectin (macrocyclic lactones; n = 8) and Strongid (pyrantel pamoate; n = 8) were administered to horses and fecal samples were collected every 14d for 98d. Samples were tested using fecal egg counts with a modified McMaster technique and 18S rRNA profiling of the V5.8 and ITS1 regions. Sequences were clustered and taxonomy was assigned against a custom NCBI Blast+ database with the aligned sequences of 19 cyathostomins. Data were analyzed using presence/absence methods in R studio. Treatment and Day significantly impacted the average number of species present (P < 0.001). Moxidectin had the lowest number of species present followed by Strongid then Ivermectin (7.14, 10.17, 11.09, respectively). Equine shedder status had no effect on the average number of species present (P > 0.05). Six species, CO. labiatus, CS. catinatum, CY. auriculatus, CY. elongatus, CT. goldi and CT. longibursatus, showed resistance to the three treatments (P > 0.05). Moxidectin was the most effective at eradicating cyathostomins infestations (P < 0.05). Identifying resistance patterns at the species level will enable mechanistic molecular approaches to determine anthelmintic resistance in cyathostomins.

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