Adjuvant Radiation Therapy Is Associated With Survival Benefit in WHO Grade 3 Astrocytomas But Not Oligodendrogliomas: Results From a Population-Based Study

Purpose. Although randomized trials suggest a survival benefit of adjuvant chemotherapy and radiation therapy (XRT) for gastric adenocarcinoma, its use in patients who undergo an extended lymphadenectomy is less clear. The purpose of this study was to determine if a survival benefit exists in gastric cancer patients who receive adjuvant XRT following resection with extended lymphadenectomy.Methods. The SEER registry was queried for records of patients with resected gastric adenocarcinoma from 1988 to 2007. Multivariable Cox regression models were used to assess independent prognostic factors affecting overall survival (OS) and disease-specific survival (DSS).Results. Of 15,060 patients identified, 3,208 (21%) received adjuvant XRT. Adjuvant XRT was independently associated with improved OS (HR 0.67, CI 0.64–0.71) and DSS (HR 0.69, CI 0.65–0.73) in stages IB through IV (M0). This OS and DSS benefit persisted regardless of the extent of lymphadenectomy. Furthermore, lymphadenectomy with >25 LN resected was associated with improved OS and DSS compared with <15 LN or 15–25 LN.Conclusion. This population-based study shows a survival benefit of adjuvant XRT following gastrectomy that persists in patients who have an extended lymphadenectomy. Furthermore, removal of >25 LNs results in improved OS and DSS compared with patients who have fewer LNs resected.

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Hypofractionated Adjuvant Radiation Therapy Is Effective for Patients With Lymph Node–Positive Breast Cancer: A Population-Based Analysis

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2020.07.2313 ◽

2020 ◽

Vol 108 (5) ◽

pp. 1150-1158

Author(s):

Theodora A. Koulis ◽

Alan M. Nichol ◽

Pauline T. Truong ◽

Caroline Speers ◽

Lovedeep Gondara ◽

...

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Lymph Node ◽

Population Based ◽

Adjuvant Radiation ◽

Adjuvant Radiation Therapy ◽

Node Positive ◽

Lymph Node Positive ◽

Positive Breast Cancer

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Survival Benefit of Adjuvant Radiation Therapy in Node-positive Vulvar Cancer

American Journal of Clinical Oncology ◽

10.1097/coc.0000000000000393 ◽

2018 ◽

Vol 41 (9) ◽

pp. 845-850 ◽

Cited By ~ 1

Author(s):

Eric P. Xanthopoulos ◽

Surbhi Grover ◽

Priya M. Puri ◽

Michael N. Corradetti ◽

Samuel P. Heilbroner ◽

...

Keyword(s):

Radiation Therapy ◽

Survival Benefit ◽

Vulvar Cancer ◽

Adjuvant Radiation ◽

Adjuvant Radiation Therapy ◽

Node Positive

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A Population-Based Comparative Outcome of Adjuvant Radiation Therapy in Patients With Soft Tissue Sarcoma of the Head and Neck

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2015.07.2169 ◽

2015 ◽

Vol 93 (3) ◽

pp. E635-E636

Author(s):

A. Brandmaier ◽

X. Wu ◽

P. Christos ◽

J.M. Mann ◽

A.G. Wernicke ◽

...

Keyword(s):

Radiation Therapy ◽

Soft Tissue ◽

Soft Tissue Sarcoma ◽

Head And Neck ◽

Population Based ◽

Adjuvant Radiation ◽

Adjuvant Radiation Therapy

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Adrenal Gland Metastasis Is an Unusual Manifestation of Endometrial Cancer

Case Reports in Surgery ◽

10.1155/2013/428456 ◽

2013 ◽

Vol 2013 ◽

pp. 1-3 ◽

Cited By ~ 3

Author(s):

Syeda Sadia Zaidi ◽

Vipul T. Lakhani ◽

Oluwole Fadare ◽

Dineo Khabele

Keyword(s):

Radiation Therapy ◽

Endometrial Cancer ◽

Adrenal Mass ◽

Endometrial Adenocarcinoma ◽

Adjuvant Radiation ◽

Unusual Manifestation ◽

Adjuvant Radiation Therapy ◽

Adrenal Gland Metastasis ◽

Grade 3 ◽

Stage 1

This case report describes a woman treated for stage 1 B grade 3 endometrial adenocarcinoma with surgery and adjuvant radiation therapy who presented 6 months later with pain and symptoms of adrenal insufficiency. A large right adrenal mass revealed adenocarcinoma consistent with the endometrial primary.

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