Voxel Dose Pattern for Patient-Reported Dysphagia Among Head and Neck Cancer Patients Receiving Definitive Radiotherapy

Author(s):  
Z. Cheng ◽  
K. Sheikh ◽  
P. Lakshminarayanan ◽  
W. Jiang ◽  
P. Han ◽  
...  
2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e22040-e22040
Author(s):  
Michael Joseph Eblan ◽  
Ja Hye Myung ◽  
Joseph M Caster ◽  
Seth M. Miller ◽  
Dominic T. Moore ◽  
...  

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1277
Author(s):  
Giuseppe Fanetti ◽  
Jerry Polesel ◽  
Elisabetta Fratta ◽  
Elena Muraro ◽  
Valentina Lupato ◽  
...  

Background: The Prognostic Nutritional Index (PNI) is a parameter of nutritional and inflammation status related to toxicity in cancer treatment. Since data for head and neck cancer are scanty, this study aims to investigate the association between PNI and acute and late toxicity for this malignancy. Methods: A retrospective cohort of 179 head and neck cancer patients treated with definitive radiotherapy with induction/concurrent chemotherapy was followed-up (median follow-up: 38 months) for toxicity and vital status between 2010 and 2017. PNI was calculated according to Onodera formula and low/high PNI levels were defined according to median value. Odds ratio (OR) for acute toxicity were calculated through logistic regression model; hazard ratios (HR) for late toxicity and survival were calculated through the Cox proportional hazards model. Results: median PNI was 50.0 (interquartile range: 45.5–53.5). Low PNI was associated with higher risk of weight loss > 10% during treatment (OR = 4.84, 95% CI: 1.73–13.53 for PNI < 50 versus PNI ≥ 50), which was in turn significantly associated with worse overall survival, and higher risk of late mucositis (HR = 1.84; 95% CI:1.09–3.12). PNI predicts acute weight loss >10% and late mucositis. Conclusions: PNI could help clinicians to identify patients undergoing radiotherapy who are at high risk of acute and late toxicity.


2015 ◽  
Vol 15 (24) ◽  
pp. 10899-10903 ◽  
Author(s):  
Sonay Arslan ◽  
Candan Demiroz Abakay ◽  
Feyza Sen ◽  
Ali Altay ◽  
Tayyar Akpinar ◽  
...  

Medicine ◽  
2016 ◽  
Vol 95 (19) ◽  
pp. e3403 ◽  
Author(s):  
Ho-Seob Kang ◽  
Jong-Lyel Roh ◽  
Sung-Bae Kim ◽  
Seung-Ho Choi ◽  
Soon Yuhl Nam ◽  
...  

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e18086-e18086
Author(s):  
Katherine Gaines ◽  
Laeticia Hollant ◽  
Bridget Smart ◽  
Megan Paige Single ◽  
Jacob Habboush ◽  
...  

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