Role of Inhibition of DNA Double-Strand Break Repair and Autophagy in Pancreatic Cancer Cytotoxicity and Radiation-Induced Cell Killing

Dna Double Strand Break ◽

Radiation Induced ◽

Suppression of radiation-induced DNA double-strand break repair by MyD88 is accompanied by apoptosis and crypt loss in mouse colon

Oncogenesis ◽

10.1038/oncsis.2013.22 ◽

2013 ◽

Vol 2 (8) ◽

pp. e62-e62 ◽

Cited By ~ 10

Author(s):

X Y Lai ◽

L J Egan

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Mouse Colon ◽

Dna Double Strand Break ◽

Radiation Induced ◽

The role of homologous recombination in radiation-induced double-strand break repair

Radiotherapy and Oncology ◽

10.1016/j.radonc.2011.06.019 ◽

2011 ◽

Vol 101 (1) ◽

pp. 7-12 ◽

Cited By ~ 125

Author(s):

Penny A. Jeggo ◽

Verena Geuting ◽

Markus Löbrich

Keyword(s):

Homologous Recombination ◽

Strand Break ◽

Double Strand Break ◽

Radiation Induced ◽

A historical reflection on our understanding of radiation-induced DNA double strand break repair in somatic mammalian cells; interfacing the past with the present

International Journal of Radiation Biology ◽

10.1080/09553002.2018.1564083 ◽

2019 ◽

Vol 95 (7) ◽

pp. 945-956 ◽

Cited By ~ 11

Author(s):

Atsushi Shibata ◽

Penny Jeggo

Keyword(s):

Mammalian Cells ◽

Strand Break ◽

Double Strand Break ◽

The Past ◽

Dna Double Strand Break ◽

Radiation Induced ◽

Break Repair ◽

Historical Reflection

MEK Inhibitor GSK1120212-Mediated Radiosensitization of Pancreatic Cancer Cells Involves Inhibition of DNA Double-Strand Break Repair Pathways

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2015.07.975 ◽

2015 ◽

Vol 93 (3) ◽

pp. E166

Author(s):

T.M. Williams ◽

A. Estrada ◽

M. Chatterjee ◽

L. Yang ◽

M.A. Morgan ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Mek Inhibitor ◽

Strand Break ◽

Double Strand Break ◽

Pancreatic Cancer Cells ◽

Dna Double Strand Break ◽

Repair Pathways ◽

Role of 53BP1 in the Regulation of DNA Double-Strand Break Repair Pathway Choice

Radiation Research ◽

10.1667/rr13572.1 ◽

2014 ◽

Vol 181 (1) ◽

pp. 1-8 ◽

Cited By ~ 62

Author(s):

Arun Gupta ◽

Clayton R. Hunt ◽

Sharmistha Chakraborty ◽

Raj K. Pandita ◽

John Yordy ◽

...

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Repair Pathway ◽

Dna Double Strand Break ◽

Pathway Choice ◽

Ionizing radiation-induced growth in soft agar is associated with miR-21 upregulation in wild-type and DNA double strand break repair deficient cells

DNA Repair ◽

10.1016/j.dnarep.2019.03.012 ◽

2019 ◽

Vol 78 ◽

pp. 37-44 ◽

Cited By ~ 2

Author(s):

Siyuan Tang ◽

Bailong Liu ◽

Min Liu ◽

Zhentian Li ◽

Jiaqi Liu ◽

...

Keyword(s):

Ionizing Radiation ◽

Strand Break ◽

Soft Agar ◽

Double Strand Break ◽

Wild Type ◽

Dna Double Strand Break ◽

Radiation Induced ◽

Tumor Cell Kill by c-MYC Depletion: Role of MYC-Regulated Genes that Control DNA Double-Strand Break Repair

Cancer Research ◽

10.1158/0008-5472.can-10-0944 ◽

2010 ◽

Vol 70 (21) ◽

pp. 8748-8759 ◽

Cited By ~ 45

Author(s):

Kaisa R. Luoto ◽

Alice X. Meng ◽

Amanda R. Wasylishen ◽

Helen Zhao ◽

Carla L. Coackley ◽

...

Keyword(s):

Tumor Cell ◽

Strand Break ◽

Double Strand Break ◽

Dna Double Strand Break ◽

Cell Kill ◽

MEK inhibitor GSK1120212-mediated radiosensitization of pancreatic cancer cells involves inhibition of DNA double-strand break repair pathways

Cell Cycle ◽

10.1080/15384101.2015.1104437 ◽

2015 ◽

Vol 14 (23) ◽

pp. 3713-3724 ◽

Cited By ~ 20

Author(s):

Adriana Estrada-Bernal ◽

Moumita Chatterjee ◽

S Jaharul Haque ◽

Linlin Yang ◽

Meredith A Morgan ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Mek Inhibitor ◽

Strand Break ◽

Double Strand Break ◽

Pancreatic Cancer Cells ◽

Dna Double Strand Break ◽

Repair Pathways ◽

The Role of the Nonhomologous End-Joining DNA Double-Strand Break Repair Pathway in Telomere Biology

Annual Review of Genetics ◽

10.1146/annurev.genet.39.110304.095755 ◽

2006 ◽

Vol 40 (1) ◽

pp. 237-277 ◽

Cited By ~ 70

Author(s):

Karel Riha ◽

Michelle L. Heacock ◽

Dorothy E. Shippen

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Nonhomologous End Joining ◽

Repair Pathway ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair ◽

Telomere Biology

The role of ATM signalling in DNA double strand break repair.

The FASEB Journal ◽

10.1096/fasebj.24.1_supplement.411.1 ◽

2010 ◽

Vol 24 (S1) ◽

Author(s):

Penelope Ann Jeggo ◽

Aaron A Goodarzi ◽

Atsushi Shibata ◽

Markus Lobrich

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Dna Double Strand Break ◽