scholarly journals Fostering a faster post-operative wound healing process with hyperbaric oxygen therapy in a rare case of squamous odontogenic tumor

2021 ◽  
pp. 106718
Author(s):  
Mendy Hatibie Oley ◽  
Maximillian Christian Oley ◽  
Meilany Feronika Durry ◽  
Rizky Natanael Adam ◽  
Deborah Florencia Gunawan ◽  
...  
Keyword(s):  
Wound Healing ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Rare Case ◽  
Oxygen Therapy ◽  
Healing Process ◽  
Odontogenic Tumor ◽  
Wound Healing Process ◽  
Operative Wound

scholarly journals Pengaruh terapi oksigen hiperbarik terhadap penyembuhan luka pada luka bakar derajat dua dalam pada hewan coba kelinci

2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Rudy H. Susilo ◽  
Mendy Hatibie ◽  
Jan T. Ngantung ◽  
Meilany F. Durry
Keyword(s):  
Wound Healing ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Healing Process ◽  
Inflammatory Cells ◽  
Wound Healing Process ◽  
Burn Wounds ◽  
Degree Burn ◽  
Second Degree

Abstract: Wound healing process consists of inflammation, proliferation, and remodelling phases with increasing inflammatory cells, angiogenesis, and epithelization. Mechanism of hyperbaric oxygen therapy is O2 pressure over 1 ATA will increase oxygen pressure in the tissue. The main outcome measure is wound healing. This study was aimed to obtain the influence of hyperbaric oxygen therapy to wound healing process of deep second degree burn wounds. This was an experimental study. Subject were 36 rabbits divided into 2 groups, each of 18 rabbits. Deep second degree burn wounds were performed on all rabbits. One group was treated with hyperbaric oxygen therapy 2.4 ATA for 6 days, meanwhile the other group as control. The result of Mann-Whitney U test showed significant differences in inflammatory cells (P = 0.025) and epithelization (P = 0.024); albeit, there was not significant difference in angiogenesis (P = 0.442) between the two groups. Conclusion: Hyperbaric oxygen therapy could influence the inflammatory cells and epithelization but not the angiogenesis.Keywords: second degree burn wound, healing process, hyperbaric oxygen therapyAbstrak: Proses penyembuhan luka terdiri dari: fase inflamasi, proliferasi, dan perupaan kembali/remodeling, yang tampak dengan meningkatnya sel-sel radang, angiogenesis serta epitelialisasi. Mekanisme kerja terapi oksigen hiperbarik (TOHB) ialah pemberian tekanan O2 yang melebihi 1 ATA akan menyebabkan peningkatan tekanan O2 dalam jaringan. Jenis penelitian ialah eksperimental. Subyek penelitian 36 ekor kelinci yang dibuat luka bakar derajat dua dalam, kemudian dibagi menjadi dua kelompok, masing-masing 18 ekor. Kelompok perlakuan diberikan TOHB dengan dosis 2,4 ATA selama 6 hari sedangkan kelompok lain sebagai kontrol. Hasil uji Mann-Whitney U menunjukkan terdapat perbedaan bermakna pada jumlah sel radang (P = 0,025) dan epitelialisasi (P = 0,024), tetapi tidak terdapat perbedaan bermakna pada angiogenesis (p=0,442), serta ada perbedaan bermakna pada pada kedua kelompok. Simpulan: Terapi oksigen hiperbarik berpengaruh terhadap jumlah sel radang dan epitelialisasi namun tidak terhadap angiogenesis.Kata kunci: penyembuhan luka bakar, oksigen hiperbarik, luka bakar derajat dua dalam

scholarly journals Terapi Oksigen Hiperbarik Meningkatkan Kualitas Hidup Pasien Glioblastoma Multiforme Stadium Akhir Dinilai Berdasarkan Neurologic Assessment Neuro Oncology Score

e-CliniC ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 556
Author(s):  
Hanni Djunadi ◽  
Maximillian Ch. Oley ◽  
Eko Prasetyo ◽  
Mendy Hatibie ◽  
Fredrik G. Langi
Keyword(s):  
Glioblastoma Multiforme ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Healing Process ◽  
Hypoxic Condition ◽  
Wound Healing Process ◽  
Before And After ◽  
End Stage ◽  
Surgery Department

Abstract: Patients with end-stage glioblastoma multiforme (GBM) that cannot be operated or treated with chemotheraphy and radiotheraphy have increased clinical complaints, thus affecting the patients’ quality of lifes (QoL). Hyperbaric oxygen therapy (HBOT) could alters hypoxic condition in tumor tissue with a different cascade from wound healing process. This study was aimed to assess whether the QoL of end-stage GBM patients could improve with the administration of HBOT assessed by decreased clinical complaints based on NANO score. The study was carried out at the Surgery Department of Prof. Dr. R. D. Kandou Hospital Manado, using pre and posttrial design. Each sample was assessed for the NANO score before HBOT, after one time, three times, five times, and 10 times of HBOT. The results showed that there was a change in the NANO score before and after 10 times of HBOT. The decrease in the NANO score occurred more quickly after the therapy. In the last two measurements, the NANO score according to the RVC model decreased from one to two units. The decreased NANO score occurred quite regularly with variations in the score that changed from time to time. In conclusion, HBOT can improve the QoL of patients with end-stage GBM and reduce the NANO score which is an assessment of clinical complaints of the patients.Keywords: glioblastoma multiforme; hyperbaric oxygen therapy; NANO score Abstrak: Penderita glioblastoma multiforme (GBM) stadium akhir yang tidak dapat dilakukan operasi, kemoterapi dan radioterapi memiliki keluhan klinis yang semakin meningkat sehingga memengaruhi kualitas hidup. Terapi oksigen hiperbarik (TOHB) dapat mengubah kondisi hipoksia pada jaringan tumor dengan kaskade yang berbeda dari proses penyembuhan luka. Penelitian ini bertujuan untuk menilai apakah kualitas hidup pasien GBM stadium akhir dapat membaik dengan pemberian TOHB, dinilai dengan menurunnya keluhan klinis berdasarkan NANO score. Penelitian dilakukan di Bagian Bedah RSUP Prof. Dr. R. D. Kandou Manado, dengan menggunakan pre and posttrial design. Pada setiap sampel dilakukan penilaian NANO score sebelum TOHB, setelah satu kali, tiga kali, lima kali, dan 10 kali TOHB. Hasil penelitian mendapatkan adanya perubahan NANO score sebelum TOHB dan setelah 10 kali TOHB. Penurunan NANO score berlangsung lebih cepat pasca terapi tersebut. Dalam dua pengukuran terakhir, NANO score menurut model RVC turun dari satu hingga dua satuan. Pada grafik, hasil penurunan NANO score terjadi cukup beraturan dengan variasi score yang berubah dari waktu ke waktu. Simpulan penelitian ini ialah TOHB dapat meningkatkan kualitas hidup penderita GBM stadium akhir dan menurunkan NANO score yang menjadi penilainan keluhan klinis penderita.Kata kunci: glioblastoma multiforme; terapi oksigen hiperbarik; NANO score

Does Hyperbaric Oxygen Therapy Work in Facilitating Acute Wound Healing

2014 ◽  
Vol 133 (2) ◽  
pp. 208e-215e ◽  
Author(s):  
Phillip B. Dauwe ◽  
Benson J. Pulikkottil ◽  
Lawrence Lavery ◽  
James M. Stuzin ◽  
Rod J. Rohrich
Keyword(s):  
Wound Healing ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Acute Wound

scholarly journals Oxidative stress is fundamental to hyperbaric oxygen therapy

2009 ◽  
Vol 106 (3) ◽  
pp. 988-995 ◽  
Author(s):  
Stephen R. Thom
Keyword(s):  
Oxidative Stress ◽  
Signal Transduction ◽  
Wound Healing ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Reactive Species ◽  
Controlled Clinical Trials ◽  
Therapeutic Mechanisms ◽  
Cell Signal Transduction

The goal of this review is to outline advances addressing the role that reactive species of oxygen and nitrogen play in therapeutic mechanisms of hyperbaric oxygen. The review will be organized around major categories of problems or processes where controlled clinical trials have demonstrated clinical efficacy for hyperbaric oxygen therapy. Reactive species are now recognized to play a major role in cell signal transduction cascades, and the discussion will focus on how hyperbaric oxygen acts through these pathways to mediate wound healing and ameliorate postischemic and inflammatory injuries.

Effects of hyperbaric oxygen therapy on uncomplicated incisional and open wound healing in dogs

2018 ◽  
Vol 47 (6) ◽  
pp. 827-836 ◽  
Author(s):  
Christian R. Latimer ◽  
Cassie N. Lux ◽  
Sarah Roberts ◽  
Marti G. Drum ◽  
Cheryl Braswell ◽  
...  
Keyword(s):  
Wound Healing ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Open Wound

The effect of hyperbaric oxygen therapy on the adverse effects of octreotide on wound healing

2004 ◽  
Vol 16 (5) ◽  
pp. 475-478 ◽  
Author(s):  
Senol Yildiz ◽  
Haldun Uluutku ◽  
Alp Gunay ◽  
I2smail Yildirim ◽  
??ukru Yildirim ◽  
...  
Keyword(s):  
Wound Healing ◽  
Adverse Effects ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy

scholarly journals Application of Local Hyperbaric Oxygen Therapy With Use of Device Laserobaria – S in the Treatment of Chronic Wounds

2016 ◽  
Vol 57 (4) ◽  
pp. 29-35
Author(s):  
Aleksander Sieroń ◽  
Jarosław Pasek ◽  
Mikołaj Pietrzak ◽  
Grzegorz Cieślar
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Chronic Wounds ◽  
Healing Process ◽  
Lower Extremities ◽  
Therapeutic Effects ◽  
Atherosclerotic Lesions ◽  
Number Of Patients ◽  
Therapeutic Mechanism

Abstract For many years now we have been observing a growing number of patients with amputations performed on lower extremities due to chronic wounds occurring as a result of atherosclerotic lesions in peripheral arteries, thromboembolism as well as due to chronic ischaemia in lower extremities. Modern physical medicine is systematically enhancing treatment possibilities for patients with chronic wounds by an introduction of innovative therapeutic devices into clinical practice, which often allow to prevent amputations, accelerate the healing process, and, most of all, alleviate or completely eliminate pain. The article presents the therapeutic mechanism and methodology of one of such methods - local hyperbaric oxygen therapy with the use of a device called LASEROBARIA - S, alongside a description of its therapeutic effects in the case of two patients.

scholarly journals BASIC MECHANISM OF HYPERBARIC OXYGEN IN INFECTIOUS DISEASE

2016 ◽  
Vol 2 (1) ◽  
pp. 49 ◽  
Author(s):  
Prihartini Widiyanti
Keyword(s):  
Infectious Disease ◽  
Wound Healing ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Side Effect ◽  
Oxygen Therapy ◽  
Basic Mechanism ◽  
Cumulative Number ◽  
Hyperbaric Chamber ◽  
Increased Pressure

Hyperbaric oxygen therapy (HBOT) is the inhalation of 100 percent oxygen inside a hyperbaric chamber that is pressurized to greater than 1 atmosphere (atm). HBOT causes both mechanical and physiologic effects by inducing a state of increased pressure and hyperoxia. HBOT is typically administered at 1 to 3 atm. While the duration of an HBOT session is typically 90 to 120 minutes, the duration, frequency, and cumulative number of sessions have not been standardized. HBO has been use widely in treating gangrene diabetic, stroke, osteomyelitis and accelerating wound healing. The use of HBO in infectious disease is wide, so the mechanism of hyperbaric oxygen in infectious disease should be well-understand. This understanding could bring the proper and wise management of infectious disease and to prevent the side effect of each therapy.

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