In this paper, a transient method for measuring heat transfer coefficients in internal cooling systems using infrared thermography is applied. The experiments are performed with a two-pass internal cooling channel connected by a 180 deg bend. The leading edge and the trailing edge consist of trapezoidal and nearly rectangular cross-sections, respectively, to achieve an engine-similar configuration. Within the channels, rib arrangements are considered for heat transfer enhancement. The test model is made of metallic material. During the experiment, the cooling channels are heated by the internal flow. The surface temperature response of the cooling channel walls is measured on the outer surface by infrared thermography. Additionally, fluid temperatures as well as fluid and solid properties are determined for the data analysis. The method for determining the distribution of internal heat transfer coefficients is based on a lumped capacitance approach, which considers lateral conduction in the cooling system walls as well as natural convection and radiation heat transfer on the outer surface. Because of time-dependent effects, a sensitivity analysis is performed to identify optimal time periods for data analysis. Results are compared with available literature data.