Diagnosis and management of intramedullary spinal cord lymphoma: A case illustration and review of literature

<p class="abstract">This presents the first documented case of high grade spinal cord astrocytoma in a pediatric patient treated at a tertiary medical center and gives a comprehensive review of literature on the most current modes of diagnosis, treatment, and prognosis. We report the case of a 7-year-old male with complaints of inability to ambulate and associated low back pain, which rapidly deteriorated to complete paraplegia. Magnetic resonance imaging (MRI) of his spine revealed an intradural intramedullary spinal cord lesion extending from T11 to L5 vertebra, with considerations of spinal astrocytoma and ependymoma. The patient underwent en bloc laminectomy on T9-L3, partial resection of the intramedullary cord tumor, and subsequent laminoplasty with mini plates and screws. Histopathologic studies showed spinal cord astrocytoma, World Health Organization (WHO) grade 3 (anaplastic type). The patient’s neurologic status did not improve after the surgery and was advised to undergo chemo-radiation therapy but was lost to follow up. Ten months post-operation, patient sought consult due to severe back pain, generalized body weakness, and difficulty of breathing and was then admitted. Patient’s condition worsened that eventually resulted to his demise.</p><p class="abstract"> </p>

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Intramedullary spinal cord metastasis arising from papillary thyroid carcinoma: A case report and review of literature

Surgical Neurology International ◽

10.4103/2152-7806.182544 ◽

2016 ◽

Vol 7 (14) ◽

pp. 375 ◽

Cited By ~ 2

Author(s):

SoubhagyaR Tripathy ◽

RamaC Deo ◽

Sanjib Mishra ◽

ManmathK Dhir ◽

PratapC Nath ◽

...

Keyword(s):

Spinal Cord ◽

Case Report ◽

Papillary Thyroid Carcinoma ◽

Thyroid Carcinoma ◽

Papillary Thyroid ◽

Review Of Literature ◽

Intramedullary Spinal Cord ◽

Spinal Cord Metastasis ◽

Intramedullary Spinal Cord Metastasis

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Lung adenocarcinoma presenting as intramedullary spinal cord metastasis: Case report and review of literature

Journal of Clinical Neuroscience ◽

10.1016/j.jocn.2018.03.030 ◽

2018 ◽

Vol 52 ◽

pp. 124-131 ◽

Cited By ~ 3

Author(s):

Neil Majmundar ◽

Belinda Shao ◽

Rachid Assina

Keyword(s):

Spinal Cord ◽

Case Report ◽

Lung Adenocarcinoma ◽

Review Of Literature ◽

Intramedullary Spinal Cord ◽

Spinal Cord Metastasis ◽

Intramedullary Spinal Cord Metastasis

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Intramedullary Spinal Cord Abscess: Illustration of Two Cases and Review of Literature

Indian Journal of Neurosurgery ◽

10.1055/s-0036-1588039 ◽

2017 ◽

Vol 06 (01) ◽

pp. 031-035

Author(s):

Raj Chandran ◽

Rajmohan Bhanuprabhakar ◽

Sivakumar Sumukhan

Keyword(s):

Spinal Cord ◽

Neurological Outcome ◽

Healthy Woman ◽

Accurate Diagnosis ◽

Review Of Literature ◽

Intramedullary Spinal Cord ◽

Source Of Infection ◽

First Case ◽

Intramedullary Spinal Cord Abscess ◽

Favorable Neurological Outcome

Intramedullary spinal cord abscess is a rare infection of the spinal cord with less than 120 cases reported since its first description by Hart in 1830. It is usually associated with abnormalities of the spinal cord or documented source of infection or immunodeficiency, requiring clinical radiological suspicion for accurate diagnosis. The first case is a middle-aged healthy woman without any underlying risk factors, presented with progressive paraparesis, in whom prompt, accurate diagnosis with contrast magnetic resonance imaging, diffusion-weighted imaging, and apparent diffusion coefficient mapping followed by early surgery was possible, which resulted in the favorable neurological outcome. The second case is a 10-year-old boy with paraparesis whose definite treatment and surgery was delayed due to a delay in accurate clinical and radiological diagnosis which resulted in poor outcomes. Hence, we try to establish that prompt diagnosis and surgical treatment can result in a favorable neurological outcome, though the prognosis, in general, is poor in this clinical condition. A review of literature in support of our cases is given.

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Intramedullary mature teratoma of spinal cord: A rare tumor with review of literature

Surgical Neurology International ◽

10.25259/sni_442_2020 ◽

2020 ◽

Vol 11 ◽

pp. 266

Author(s):

Ashish Acharya ◽

Sarvpreet Singh Grewal ◽

Shivender Sobti ◽

Paul Sudhakar John ◽

Ravindra Kumar Bind ◽

...

Keyword(s):

Spinal Cord ◽

Mature Teratoma ◽

Clinical Findings ◽

Review Of Literature ◽

Spinal Cord Lesions ◽

Total Resection ◽

Partial Removal ◽

Intramedullary Spinal Cord ◽

Intramedullary Lesion ◽

Extensor Hallucis Longus

Background: Spinal teratomas are rare in adults. The clinical findings are nonspecific, reflecting only in the intramedullary location of these lesions. The potential differential diagnosis for intramedullary spinal teratomas include schwannomas, dermoids, epidermoids, and neurofibromas. Case Description: A 25-year-old male presented with RLE weakness (iliopsoas/quadriceps [4/5], and extensor hallucis longus/dorsiflexor [0/5]) and urinary incontinence. As the contrast, MR showed a heterogeneous intramedullary lesion with well-defined edges located at the T12-L1 level, the patient underwent a focal laminectomy for gross total tumor excision. Pathologically, it proved to be a mature teratoma. Conclusion: Teratomas should be considered among the differential diagnostic considerations for intramedullary spinal cord lesions. Although gross total resection is preferred, these lesions have a low recurrence rate, and therefore, partial removal is also valid, where lesions are densely adherent to adjacent neural structures.

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