Chemical composition, anticancer activities and related mechanisms of the essential oil from Alpinia coriandriodora rhizome

2022 ◽  
Vol 176 ◽  
pp. 114328
Author(s):  
Yi Hong ◽  
Xiongli Liu ◽  
Huijuan Wang ◽  
Min Zhang ◽  
Minyi Tian
2013 ◽  
Vol 8 (1) ◽  
pp. 1934578X1300800
Author(s):  
Yu-Chang Su ◽  
Chen-Lung Ho

This study investigated the chemical composition and in-vitro cytotoxic activities of the essential oil isolated from the leaf of Beilschmiedia erythrophloia. The essential oil was isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC-FID and GC-MS. Fifty-five compounds were identified, representing 100% of the oil. The main components identified were β-caryophyllene (22.6%), α-humulene (21.9%), terpinen-4-ol (5.3%), cis-β-ocimene (5.1%), sabinene (5.0%) and limonene (4.5%). The anticancer activities of oil were evaluated. The results showed that the oil exhibited cytotoxic activity against human oral, liver, lung, colon, melanoma, and leukemic cancer cells.


2013 ◽  
Vol 8 (4) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Yu-Chang Su ◽  
Kuan-Ping Hsu ◽  
Eugene I-Chen Wang ◽  
Chen-Lung Ho

This study investigated the chemical composition and in vitro anticancer activities of the essential oil isolated from the leaf of Neolitsea variabillima. The essential oil was isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC-FID and GC-MS. Sixty-seven compounds were identified, representing 100% of the oil. The main components identified were trans-β-ocimene (13.4%), α-cadinol (10.5%), terpinen-4-ol (9.3%), τ-cadinol (9.2%), β-caryophyllene (8.8%), and sabinene (6.7%). The anticancer activities of oil were evaluated. The results showed that the oil exhibited cytotoxic activity against human oral, liver, lung, colon, melanoma, and leukemic cancer cells. The presence of β-caryophyllene, τ-cadinol, and α-cadinol significantly contributed to the anticancer activities of N. variabillima leaf oil.


2007 ◽  
Vol 2 (12) ◽  
pp. 1934578X0700201 ◽  
Author(s):  
Muriel Sylvestre ◽  
André Pichette ◽  
Angélique Longtin ◽  
Marie-Anna Couppé De Ker Martin ◽  
Sylvie Rodin Bercion ◽  
...  

The essential oil of Hedyosmum arborescens Sw. (Chloranthaceae), a native plant of the Caribbean archipelago, was extracted by hydrodistillation. The chemical composition of the volatile fraction was determined by GC and GC-MS analyses and 50 components were identified. The major components are α-phellandrene (11.4%), bicyclogermacrene (10.6%) and sabinene (9.7%). The anticancer activities of these extracts were assessed against human lung carcinoma cell line A-549 and human colon adenocarcinoma cell line DLD-1. The leaf essential oil of H. arborescens was found to be moderately active against both cancer cell lines with GI50 values of 158 ± 7 μg/mL for A-549 and 178 ± 9 μg/mL for DLD-1.


Molecules ◽  
2020 ◽  
Vol 25 (6) ◽  
pp. 1284 ◽  
Author(s):  
Piotr Sugier ◽  
Joanna Jakubowicz-Gil ◽  
Danuta Sugier ◽  
Radosław Kowalski ◽  
Urszula Gawlik-Dziki ◽  
...  

Arnica montana L. is a medicinal plant with diverse biological activities commonly used in pharmacy and cosmetics. The attributes of A. montana are mainly related to the concentration and chemical composition of essential oils (EOs). Therefore, the objective of this study was to characterize the chemical composition of EOs derived from A. montana rhizomes and roots taking into account the age of the plants and to investigate the effect of the analyzed EOs on induction of apoptosis, necrosis, and autophagy in human glioblastoma multiforme T98G and anaplastic astrocytoma MOGGCCM cell lines. Rhizomes and roots of mountain arnica were harvested at the end of the third and fourth vegetation periods. The chemical composition of essential oils was determined with the GC–MS technique. Among the 37 components of the essential oil of A. montana, 2,5-dimethoxy-p-cymene (46.47%–60.31%), 2,6-diisopropylanisole (14.48%–23.10%), thymol methyl ether (5.31%–17.79%), p-methoxyheptanophenone (5.07%–9.65%), and α-isocomene (0.68%–2.87%), were detected in the rhizomes and roots of the three-year-old plants and in the rhizomes and roots of the four-year-old plants. The plant part (rhizome, root) and plant age can be determinants of the essential oil composition and, consequently, their biological activity. The induction of apoptosis (but not autophagy nor necrosis) at a level of 28.5%–32.3% is a promising result, for which 2,5-dimethoxy-p-cymene, 2,6-diisopropylanisole, thymol methyl ether, and p-methoxyheptanophenone are probably mainly responsible. The present study is the first report on the anticancer activities of essential oils from A. montana rhizomes and roots.


Molecules ◽  
2015 ◽  
Vol 20 (9) ◽  
pp. 15781-15796 ◽  
Author(s):  
Guan-Ling Xu ◽  
Di Geng ◽  
Meng Xie ◽  
Kai-Yue Teng ◽  
Yu-Xin Tian ◽  
...  

2019 ◽  
Vol 34 (18) ◽  
pp. 2621-2625 ◽  
Author(s):  
Minyi Tian ◽  
Tingting Liu ◽  
Xianghuan Wu ◽  
Yi Hong ◽  
Xiongli Liu ◽  
...  

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