The role of epidemiology in improving the evidence base in injury prevention and trauma care

Injury ◽  
2012 ◽  
Vol 43 (4) ◽  
pp. 395-396 ◽  
Author(s):  
Rebecca Q. Ivers
2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
R E Fraser ◽  
G R Layton ◽  
L L Kuan ◽  
A R Dennison

Abstract Background Cavernous hepatic haemangiomas are benign liver tumours and although common when small, giant haemangiomas (usually accepted as being greater than 10cm) are infrequent. Treatment is indicated in patients who are symptomatic or if diagnosis is unclear, although with giant haemangiomas, many support expectant management of asymptomatic lesions due to the risk of major complications. Traditionally hepatic resection has been the primary treatment option for these lesions, but a variety of other techniques, including enucleation, have been described as safe and effective alternatives. There remains equipoise in respect of the best management of giant haemangiomas above 10cm. Cases of such size are rare and so there is a paucity of data available. Case presentation We present a case of a 65-year-old male who underwent successful anatomical liver resection for a 5kg giant cavernous haemangioma of 26cm diameter following its incidental identification during an ultrasound scan. We also discuss and compare the role of resection and enucleation for the treatment of haemangiomata greater than 20cm in diameter. Conclusions This case demonstrates successful resection of an unusually giant haemangioma which, in contrast to the majority of literature, provides a valuable addition to the limited evidence base for management of this condition by anatomical resection.


Gut Pathogens ◽  
2021 ◽  
Vol 13 (1) ◽  
Author(s):  
A. L. Cunningham ◽  
J. W. Stephens ◽  
D. A. Harris

AbstractA strong and expanding evidence base supports the influence of gut microbiota in human metabolism. Altered glucose homeostasis is associated with altered gut microbiota, and is clearly associated with the development of type 2 diabetes mellitus (T2DM) and associated complications. Understanding the causal association between gut microbiota and metabolic risk has the potential role of identifying susceptible individuals to allow early targeted intervention.


2020 ◽  
pp. 1-7
Author(s):  
Alejandro Javaloyes ◽  
Manuel Mateo-March ◽  
Felipe P. Carpes ◽  
Manuel Moya-Ramon ◽  
Raúl Lopez-Grueso ◽  
...  

BACKGROUND: Pedalling asymmetries are a topic of interest to cycling coaches and athletes due to a potential link with performance and injury prevention. OBJECTIVES: The aim of this study is to describe the bilateral asymmetry of professional cyclists during two editions of a Grand Tour. METHODS: Here we set out to determine the power balance (power produced by each lower limb) between stronger and weaker leg (dominant vs. non-dominant) of 12 UCI professional cyclists competing at two Giro d’Italia editions. Power data were recorded during competition stages. Further analysis considered power data clustered into individual intensity zones (from Z1 to Z7). RESULTS: Higher intensity elicited better power balance (lower asymmetry) regardless of the stage profile. Intensity distribution analysed according to the role of the cyclist was lower for climbers in Z2 (p= 0.006) and Z7 (p= 0.002) and higher in Z5 (p= 0.023) compared to team helpers. Power balance ranged from 0 to 9 % across the different athletes. CONCLUSIONS: Increase in power output improves power balance, especially in team helpers, and the lower power balance at lower exercise intensities, which are most of the race time, may elicit significant cumulative loading on a given leg of the cyclists, which requires further attention regarding risks of overuse injury.


2017 ◽  
Vol 60 (2) ◽  
pp. S17
Author(s):  
Alison J. Culyba ◽  
Elizabeth Miller ◽  
Kenneth R. Ginsburg ◽  
Charles C. Branas ◽  
Wensheng Guo ◽  
...  

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