37.1 Review of Current Risk Assessment Practices

2018 ◽  
Vol 57 (10) ◽  
pp. S53-S54
Author(s):  
Sophia A. Walker
2006 ◽  
Vol 25 (1) ◽  
pp. 19-21 ◽  
Author(s):  
K A Mundt

The US Environmental Protection Agency (EPA) recently issued a Staff Paper that articulates current risk assessment practices. In section 4.1.3, EPA states,“...effects that appear to be adaptive, non–adverse, or beneficial may not be mentioned.” This statement may be perceived as precluding risk assessments based on non–default risk models, including the hormetic–or biphasicdose–response model. This commentary examines several potential interpretations of this statement and the anticipated impact of ignoring hormesis, if present, in light of necessary conservatism for protecting human and environmental health, and the potential for employing alternative risk assessment approaches.


2017 ◽  
Vol 38 ◽  
pp. 76-82
Author(s):  
Sara Lospitao-Gómez ◽  
Tomás Sebastián-Viana ◽  
José M. González-Ruíz ◽  
Joaquín Álvarez-Rodríguez

2010 ◽  
Vol 29 (4) ◽  
pp. 249-261 ◽  
Author(s):  
Edward J Calabrese

This paper summarizes numerous conceptual and experimental advances over the past two decades in the study of hormesis. Hormesis is now generally accepted as a real and reproducible biological phenomenon, being highly generalized and independent of biological model, endpoint measured and chemical class/physical stressor. The quantitative features of the hormetic dose response are generally highly consistent, regardless of the model and mechanism, and represent a quantitative index of biological plasticity at multiple levels of biological organization. The hormetic dose-response model has been demonstrated to make far more accurate predictions of responses in low dose zones than either the threshold or linear at low dose models. Numerous therapeutic agents widely used by humans are based on the hormetic dose response and its low dose stimulatory characteristics. It is expected that as low dose responses come to dominate toxicological research that risk assessment practices will incorporate hormetic concepts in the standard setting process.


2018 ◽  
Vol 199 (4S) ◽  
Author(s):  
Taimur T Shah ◽  
Max Peters ◽  
Enrique Gomez-Gomez ◽  
Hashim U. Ahmed ◽  
Mathias Winkler

2021 ◽  
Vol 10 (3) ◽  
pp. 177-190
Author(s):  
Charlotte Barlow ◽  
Sandra Walklate ◽  
Kelly Johnson

The limits of inter-agency understandings of risk in the context of intimate partner violence are well documented. Informed by Hester’s (2011) ‘three planet’ analogy and using empirical data in one police force area in the south of England, this paper offers an exploration of intra-agency operations, focusing on police risk assessment practices. Exploring the policing risk lens and the victim-survivor journey together, findings highlight police operate with at least three risk assessment moments (call hander, front-line and Safeguarding Hub) and point to the tensions that result when failing to centralise victim-survivors’ own assessment of their risk. Using complexity theory, this paper examines the complex interplay of risk that occurs when the victim-survivor risk journey intersects with the policing aspect of the criminal justice process.


2018 ◽  
Vol 52 (4) ◽  
pp. 1690-1692
Author(s):  
Henriette Selck ◽  
Valery E. Forbes
Keyword(s):  

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