Costs of tumor necrosis factor blockers per treated patient with psoriatic disease using real-world drug usation data in a US managed care population

2013 ◽  
Vol 68 (4) ◽  
pp. AB196
2013 ◽  
Vol 19 (8) ◽  
pp. 621-630 ◽  
Author(s):  
Vernon F. Schabert ◽  
Crystal Watson ◽  
George J. Joseph ◽  
Paige Iversen ◽  
Chakkarin Burudpakdee ◽  
...  

Author(s):  
David L Kaplan ◽  
Brian L Ung ◽  
Corey Pelletier ◽  
Chuka Udeze ◽  
Ibrahim Khilfeh ◽  
...  

Aim: Real-world treatment data for psoriatic arthritis are limited. We evaluated switch rates, adherence, and costs for patients initiating apremilast versus tumor necrosis factor inhibitor (TNFi) and interleukin inhibitor (ILi) among biologic-naive psoriatic arthritis patients. Materials & methods: This retrospective analysis used IBM MarketScan claims data to assess treatment switches, adherence and costs. Results: Twelve-month switch rates were significantly lower for apremilast versus TNFi (15.5% vs 26.6%; p < 0.0001) and similar to ILi (15.5% vs 14.0%; p = 0.71). Apremilast initiators had lower total costs versus TNFi and ILi (US$39,854 vs US$57,243 and US$65,687; p < 0.05) and adherence was slightly lower versus TNFi and higher versus ILi. Conclusion: Biologic-naive apremilast initiators had lower switch rates versus TNFi initiators and lower total costs versus TNFi or ILi initiators.


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