Retention and adherence real life to psoriasis treatment and health care efficiency (retrospective observational and prospective cohort study on the persistence biologic treatments in patients with psoriasis)

2014 ◽  
Vol 70 (5) ◽  
pp. AB183
Keyword(s):  
Health Care ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Real Life ◽  
Psoriasis Treatment ◽  
Health Care Efficiency

scholarly journals SARS-CoV-2–Specific Neutralizing Antibody Responses in Norwegian Health Care Workers After the First Wave of COVID-19 Pandemic: A Prospective Cohort Study

2020 ◽  
Author(s):  
Mai-Chi Trieu ◽  
Amit Bansal ◽  
Anders Madsen ◽  
Fan Zhou ◽  
Marianne Sævik ◽  
...  
Keyword(s):  
Health Care ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Health Care Workers ◽  
Prospective Cohort ◽  
Neutralizing Antibodies ◽  
Rt Pcr ◽  
Patient Exposure ◽  
Specific Antibodies ◽  
Care Workers

Abstract Background During the coronavirus disease 2019 (COVID-19) pandemic, many countries experienced infection in health care workers (HCW) due to overburdened health care systems. Whether infected HCW acquire protective immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unclear. Methods In a Norwegian prospective cohort study, we enrolled 607 HCW before and after the first COVID-19 wave. Exposure history, COVID-19–like symptoms, and serum samples were collected. SARS-CoV-2–specific antibodies were characterized by spike-protein IgG/IgM/IgA enzyme-linked immunosorbent and live-virus neutralization assays. Results Spike-specific IgG/IgM/IgA antibodies increased after the first wave in HCW with, but not in HCW without, COVID-19 patient exposure. Thirty-two HCW (5.3%) had spike-specific antibodies (11 seroconverted with ≥4-fold increase, 21 were seropositive at baseline). Neutralizing antibodies were found in 11 HCW that seroconverted, of whom 4 (36.4%) were asymptomatic. Ninety-seven HCW were tested by reverse transcriptase polymerase chain reaction (RT-PCR) during follow-up; 8 were positive (7 seroconverted, 1 had undetectable antibodies). Conclusions We found increases in SARS-CoV-2 neutralizing antibodies in infected HCW, especially after COVID-19 patient exposure. Our data show a low number of SARS-CoV-2–seropositive HCW in a low-prevalence setting; however, the proportion of seropositivity was higher than RT-PCR positivity, highlighting the importance of antibody testing.

Performance of SLE responder index and lupus low disease activity state in real life: A prospective cohort study

2019 ◽  
Vol 22 (9) ◽  
pp. 1752-1761 ◽  
Author(s):  
Giuseppe A. Ramirez ◽  
Valentina Canti ◽  
Lucia Moiola ◽  
Marco Magnoni ◽  
Patrizia Rovere‐Querini ◽  
...  
Keyword(s):  
Cohort Study ◽  
Disease Activity ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Real Life ◽  
Low Disease Activity ◽  
Activity State

scholarly journals Risk of COVID-19 among front-line health-care workers and the general community: a prospective cohort study

2020 ◽  
Vol 5 (9) ◽  
pp. e475-e483 ◽  
Author(s):  
Long H Nguyen ◽  
David A Drew ◽  
Mark S Graham ◽  
Amit D Joshi ◽  
Chuan-Guo Guo ◽  
...  
Keyword(s):  
Health Care ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Health Care Workers ◽  
Prospective Cohort ◽  
Front Line ◽  
Care Workers ◽  
General Community
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