Is erythema dyschromicum perstans a variant of lichen planus? A case of erythema dyschromicum perstans presenting concurrently with lichen planus nail changes without any other cutaneous manifestations of lichen planus

2018 ◽  
Vol 79 (3) ◽  
pp. AB171
2021 ◽  
pp. 1-10
Author(s):  
Bipasha Roy ◽  
Shari R. Lipner

Acrokeratosis paraneoplastica (Bazex syndrome) is a rare paraneoplastic dermatosis associated with internal malignancies. Clinical presentation is characterized by erythematous or violaceous scaly plaques involving the digits, nose, ears, palms, and soles. Nail changes commonly present concurrently with cutaneous manifestations. In this review, we characterize nail changes associated with acrokeratosis paraneoplastica. A total of 48 cases were analyzed. Nail findings were nonspecific, with the most common being nail plate thickening, onycholysis, subungual hyperkeratosis, longitudinal ridging, discoloration, and nail plate loss. In most patients, nail changes involved the majority of fingernails and toenails and most often appeared prior to the diagnosis of malignancy. The most common associated underlying malignancies were squamous cell carcinomas of the head and neck. A diagnosis of acrokeratosis paraneoplastica should be considered in patients with onychodystrophy involving multiple nails with accompanying atypical psoriasiform dermatoses. Screening for internal malignancies may significantly decrease morbidity and mortality for these patients.


2000 ◽  
Vol 142 (4) ◽  
pp. 848-849 ◽  
Author(s):  
A. Tosti ◽  
B.M. Piraccini ◽  
N. Cameli

2020 ◽  
pp. 120347542098255
Author(s):  
Magdalena Żychowska ◽  
Małgorzata Żychowska

Background Lichen planus (LP) is an inflammatory condition that can affect skin, mucous membranes, hair follicles, and/or nails. Nail abnormalities are estimated to occur in around 10% of LP cases. Clinical characteristics of nail involvement have been the subject of very few studies, which have mainly focused on isolated nail LP. Objectives To identify and describe nail alterations in patients with LP. Methods Seventy-five patients with cutaneous lichen planus (CLP) were included in the study. The diagnosis of LP was histologically confirmed in each case. Onychomycosis was excluded in each patient. Results Nail lesions were present in 21 (28%) patients (mean age 58.1 ± 12.55 years) with CLP. On an average, patients had 9.38 nails affected. A slight female preponderance was noted (57%). Nail involvement was independent of age, gender, presence of pruritus, the affected skin area, or the duration of CLP. The most common finding in the fingernails ( n = 122) was longitudinal ridging (85.2%), followed by nail plate thinning (38.2%) and onycholysis (17.2%). Pterygium formation (6.6%) and red lunulae (8.2%) were limited to the fingernails. In the fingernails, matrix involvement (98.4%) was more frequent than nail bed involvement (27%). The most common finding in the toenails ( n = 75) was hyperkeratosis (82.7%) with yellowish discoloration (69.3%). No cases of trachyonychia or anonychia were noted. Conclusions Nail abnormalities in patients with CLP may be more common than initially assessed. Rare formation of pterygium and absence of anonychia in patients with predominant cutaneous involvement might point at mild course of the nail disease in such cases.


Author(s):  
ISABELLE SATURNINO CORRÊA ◽  
GABRIEL GOMES DA SILVA ◽  
LUIZ MIGUEL DA ROCHA SANTOS ◽  
JULIANA CAMPOS PINHEIRO ◽  
EVERTON FREITAS DE MORAIS ◽  
...  

Author(s):  
Aashim Singh ◽  
Saurabh Bhatia ◽  
Somesh Gupta
Keyword(s):  

2017 ◽  
Vol 63 (6) ◽  
pp. 481-483 ◽  
Author(s):  
Clarissa Prieto Herman Reinehr ◽  
Célia Luiza Petersen Vitello Kalil ◽  
Vinícius Prieto Herman Reinehr

Summary Syphilis is an infection caused by Treponema pallidum, mainly transmitted by sexual contact. Since 2001, primary and secondary syphilis rates started to rise, with an epidemic resurgence. The authors describe an exuberant case of secondary syphilis, presenting with annular and lichen planus-like lesions, as well as one mucocutaneous lesion. Physicians must be aware of syphilis in daily practice, since the vast spectrum of its cutaneous manifestations is rising worldwide.


Author(s):  
Bikash Narayan Choudhury ◽  
Anita Jain ◽  
Urmila Das Baruah

<p class="abstract"><strong>Background:</strong> The present study was conducted to assess the spectrum of cutaneous changes in chronic liver disease and to assess any correlation between the skin findings and the type of the liver disease.</p><p class="abstract"><strong>Methods:</strong> A total of 100 patients above 18 years of age suffering from chronic liver disease with cutaneous manifestations and attending the Gastroenterology and Dermatology and Venereology department of Gauhati Medical College and Hospital, Guwahati, India during the period from June 2016 to May 2017 were included in the study.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 100 cases, there were 84 males (84%) and 16 females (16%) with the male to female ratio of 5.25:1. Alcoholic liver disease comprised 62% of the patients in the study, other causes being cryptogenic liver disease (14%), chronic hepatitis infection (12%), Wilson’s disease (2%), autoimmune hepatitis (2%), hepatocellular carcinoma (2%), methotrexate induced liver disease (1%) and non-alcoholic steatohepatitis (1%). Most common skin finding was xerosis (62%). Other key findings included nail changes (60%), pigmentary changes (55%), hair changes (50%), jaundice (40%), cutaneous infections (31%), pruritus (27%).</p><p class="abstract"><strong>Conclusions:</strong> Patients with chronic liver disease can have a wide spectrum of cutaneous manifestations the most important being xerosis, nail changes, pigmentary changes, hair changes, jaundice, infections, pruritus and spider angioma. These changes can give a clue to the presence of the underlying liver disease and its severity. Hence, identifying these signs earlier can lead to prompt diagnosis and effective management of the underlying condition, thereby preventing its complications.</p>


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