Nail changes in lichen planus may resemble those of yellow nail syndrome

2000 ◽  
Vol 142 (4) ◽  
pp. 848-849 ◽  
Author(s):  
A. Tosti ◽  
B.M. Piraccini ◽  
N. Cameli
PEDIATRICS ◽  
1992 ◽  
Vol 89 (6) ◽  
pp. 1016-1018
Author(s):  
Paul Govaert ◽  
Jules G. Leroy ◽  
Romain Pauwels ◽  
Piet Vanhaesebrouck ◽  
Claudine De Praeter ◽  
...  

A term female firstborn infant had unexplained nonimmune fetal hydrops and recurrent left chylothorax at 4 weeks of age. A few months before conception, her mother had had acute dystrophic nail changes and is being treated for recurrent sinusitis, bronchiectasis, and a deficiency of serum IgG2. We suggest that they both suffer from a dominantly inherited congenital lymphedema syndrome known as `yellow nail dystrophy.' Prenatal manifestation of this disorder has not been reported previously. The child's anthropometric and neurological development was normal at 1 year of age, whereas mild ankle edema and marbling of the skin of the limbs were salient clinical findings. Inherited lymphedema leading to nonimmune fetal hydrops also has been recognized in chromosomal disorders, Noonan's syndrome, multiple pterygium syndrome, pulmonary lymphangiectasis, and mixed-vessel lymphatic dysfunction. Indicators of parental lymphedema are not on record in those instances.


2020 ◽  
pp. 120347542098255
Author(s):  
Magdalena Żychowska ◽  
Małgorzata Żychowska

Background Lichen planus (LP) is an inflammatory condition that can affect skin, mucous membranes, hair follicles, and/or nails. Nail abnormalities are estimated to occur in around 10% of LP cases. Clinical characteristics of nail involvement have been the subject of very few studies, which have mainly focused on isolated nail LP. Objectives To identify and describe nail alterations in patients with LP. Methods Seventy-five patients with cutaneous lichen planus (CLP) were included in the study. The diagnosis of LP was histologically confirmed in each case. Onychomycosis was excluded in each patient. Results Nail lesions were present in 21 (28%) patients (mean age 58.1 ± 12.55 years) with CLP. On an average, patients had 9.38 nails affected. A slight female preponderance was noted (57%). Nail involvement was independent of age, gender, presence of pruritus, the affected skin area, or the duration of CLP. The most common finding in the fingernails ( n = 122) was longitudinal ridging (85.2%), followed by nail plate thinning (38.2%) and onycholysis (17.2%). Pterygium formation (6.6%) and red lunulae (8.2%) were limited to the fingernails. In the fingernails, matrix involvement (98.4%) was more frequent than nail bed involvement (27%). The most common finding in the toenails ( n = 75) was hyperkeratosis (82.7%) with yellowish discoloration (69.3%). No cases of trachyonychia or anonychia were noted. Conclusions Nail abnormalities in patients with CLP may be more common than initially assessed. Rare formation of pterygium and absence of anonychia in patients with predominant cutaneous involvement might point at mild course of the nail disease in such cases.


Author(s):  
Aashim Singh ◽  
Saurabh Bhatia ◽  
Somesh Gupta
Keyword(s):  

2020 ◽  
Vol 6 (5) ◽  
Author(s):  
Eckart Haneke

Yellow nail syndrome (YNS) is a rare, but relatively well characterized triad of slow growing yellow nails, lymphedema of the distal portions of the upper and lower limbs as well as chronic infection of the respiratory tract and/or pleural effusion. The most characteristic features of this syndrome are the nail changes that allow the diagnosis to be made even if the triad is not complete. Yellow discoloration of the nails is nonspecific and often seen in onychomycosis, nail psoriasis, a variety of other conditions that are associated with onycholysis. Distal limb edema may not be very pronounced. In addition to the bronchopulmonary disorders, malignancies, chronic heart conditions and gastrointestinal diseases may occur. Treatment after exclusion of non-YNS conditions is aimed at finding the underlying systemic disorder, which usually requires a very long therapy and a lot of patience both from the patient as well as the treating physician.


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