scholarly journals Use of brain natriuretic peptide levels for risk assessment in non–ST-elevation acute coronary syndromes**Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology.

2003 ◽  
Vol 42 (11) ◽  
pp. 1917-1920 ◽  
Author(s):  
Harvey D White ◽  
John K French
Keyword(s):  
Risk Assessment ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Acute Coronary Syndromes ◽  
Coronary Syndromes ◽  
St Elevation

The prognostic value of N-terminal pro-brain natriuretic peptide in non-ST elevation acute coronary syndromes: a meta-analysis

2012 ◽  
Vol 50 (4) ◽  
Author(s):  
Xiaocong Zeng ◽  
Lang Li ◽  
Qiang Su
Keyword(s):  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Predictive Value ◽  
Acute Coronary Syndromes ◽  
Meta Analysis ◽  
Predictive Values ◽  
Relative Risks ◽  
Increased Risk ◽  
Coronary Syndromes ◽  
St Elevation

AbstractPrecise risk stratification is important in patients with non-ST elevation acute coronary syndromes (NSTE-ACS) on determination for hospitalization and intensity of treatment. A meta-analysis was performed in studies of patients with NSTE-ACS to evaluate the predictive nature of elevated N-terminal pro-brain natriuretic peptide (NT-proBNP).Online searches were conducted using database to identify suitable studies. A summary of relative risks (RRs) for death and myocardial infarction (MI) was calculated using random-effects modeling. We also calculated the pooled sensitivity, specificity, positive predictive value, and negative predictive value.Thirteen studies were included. Elevated NT-proBNP levels were significantly associated with mortality [RR 4.89; 95% confidence interval (CI) 3.85–6.22] and incidence of MI (RR 1.66; 95% CI 1.24–2.22). The sensitivity and specificity for MI was 69.1% (95% CI 66.6%–71.6%) and 43.6% (95% CI 42.9%–44.3%), respectively, along with the positive and negative predictive values for MI of 8.2% (95% CI 7.7%–8.7%) and 95.1% (95% CI 94.6%–95.5%), respectively.Meta-analysis suggests that elevated NT-proBNP levels were associated with an increased risk for MI or death in patients with NSTE-ACS. Normal levels of NT-proBNP are certainly more helpful when selecting NSTE-ACS patients with likelihood for favorable outcomes.

scholarly journals N-Terminal Pro-Brain Natriuretic Peptide on Admission Has Prognostic Value Across the Whole Spectrum of Acute Coronary Syndromes

Circulation ◽  
2004 ◽  
Vol 110 (2) ◽  
pp. 128-134 ◽  
Author(s):  
Marcello Galvani ◽  
Filippo Ottani ◽  
Luigi Oltrona ◽  
Diego Ardissino ◽  
Gian Franco Gensini ◽  
...  
Keyword(s):  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Acute Coronary Syndromes ◽  
Prognostic Value ◽  
Coronary Syndromes

B-type natriuretic peptide blood levels identify patients with non-ST elevation acute coronary syndromes at high risk for complications during intravenous beta-blocker infusion

2011 ◽  
Vol 13 (3) ◽  
pp. 129-135 ◽  
Author(s):  
Nikolaos I Nikolaou ◽  
Michalis J Koutouzis ◽  
Apostolos Christou ◽  
Georgios M Fournarakis ◽  
Sotirios P Patsilinakos ◽  
...  
Keyword(s):  
High Risk ◽  
Natriuretic Peptide ◽  
Beta Blocker ◽  
Acute Coronary Syndromes ◽  
Blood Levels ◽  
Coronary Syndromes ◽  
St Elevation

B-type natriuretic peptide as an integrated risk marker in non-ST elevation acute coronary syndromes

2006 ◽  
Vol 111 (2) ◽  
pp. 224-230 ◽  
Author(s):  
Takeshi Yamamoto ◽  
Naoki Sato ◽  
Masahiro Yasutake ◽  
Hiromichi Takagi ◽  
Norishige Morita ◽  
...  
Keyword(s):  
Natriuretic Peptide ◽  
Acute Coronary Syndromes ◽  
Risk Marker ◽  
Integrated Risk ◽  
Coronary Syndromes ◽  
St Elevation
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