scholarly journals TCT-189 Syntax Score-based Assessment For Identifying Priority Of Second Generation Drug Eluting Stent Among All Comer Patients Who Underwent Percutaneous Coronary Intervention

2013 ◽  
Vol 62 (18) ◽  
pp. B62
Author(s):  
Masanori Shiba ◽  
Tadashi Araki ◽  
Yoshinori Nagashima ◽  
Kenji Yamazaki ◽  
Masahide Tokue ◽  
...  
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Second Generation ◽  
Coronary Intervention ◽  
Drug Eluting Stent ◽  
Syntax Score ◽  
Percutaneous Coronary ◽  
Drug Eluting

P45945-years clinical outcomes of patients underwent percutaneous coronary intervention for calcified lesions with rotational atherectomy and second-generation drug eluting stent

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
K Ogata ◽  
H Koiwaya ◽  
K Shinzato ◽  
Y Goriki ◽  
G Yoshioka ◽  
...  
Keyword(s):  
Risk Factors ◽  
Percutaneous Coronary Intervention ◽  
Clinical Outcomes ◽  
Second Generation ◽  
Coronary Intervention ◽  
Drug Eluting Stent ◽  
Diabetic Mellitus ◽  
Percutaneous Coronary ◽  
Drug Eluting

Abstract Background Percutaneous coronary Intervention (PCI) with rotational atherectomy (RA) was useful for severe calcified lesions. However, the long-term clinical outcomes of PCI with second-generation drug eluting stent (DES) following RA has been still unclear. Purpose The purpose of this study was to investigate the long-term clinical outcomes of RA followed by second-generation DES. Methods We retrospectively enrolled 254 consecutive patients treated with second-generation DES following RA. The primary outcome was the cumulative 5-year incidence of MACE, defined as cardiac death, myocardial infarction, clinically-driven target lesion revascularization and definite stent thrombosis. Results The incidence of MACE was 22.8% at 5-years. Multivariate analysis showed 3 predictors of MACE, hemodialysis, diabetic mellitus and extremely angulated lesions (>90°).Significantly higher MACE was observed in the high-risk (≥2 risk factors) group, compared with the low-risk (2< risk factors) group (68.7% vs. 18.7%, P<0.001, Figure). Multivariate analysis for MACE at 5 year Hazard ratio (95% Confidence Interval) P-value Diabetic Mellitus 2.58 (1.35–4.91) 0.004 Hemodialysis 4.57 (1.64–12.76) 0.004 extremely angulated (>90°) 3.08 (1.06–8.93) 0.04 Kaplan-Meier curves for 5-years MACE Conclusions The long-term clinical outcomes of PCI for severely calcified lesions was acceptable. However, the clinical outcomes of patients classified high risk cohort was unsatisfactory.

Efficacy and Safety of Percutaneous Coronary Intervention for Elderly Patients in the Second-Generation Drug-Eluting Stent Era: The SHINANO Registry

Angiology ◽  
2016 ◽  
Vol 68 (8) ◽  
pp. 688-697 ◽  
Author(s):  
Takashi Miura ◽  
Yusuke Miyashita ◽  
Hirohiko Motoki ◽  
Hideki Kobayashi ◽  
Masanori Kobayashi ◽  
...  
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Elderly Patients ◽  
Cardiac Death ◽  
Second Generation ◽  
Coronary Intervention ◽  
Major Adverse Cardiovascular Events ◽  
Drug Eluting Stent ◽  
Percutaneous Coronary ◽  
Significant Difference ◽  
Drug Eluting

Background: We evaluated the 1-year outcomes of percutaneous coronary intervention (PCI) for elderly patients (aged ≥ 80 years) in the second-generation drug-eluting stent (DES) era. Methods and Results: Between August 2012 and July 2013, 1923 consecutive patients (mean age, 71 ± 11 years; ≥80 years, 23%; men, 77%) who underwent 2250 elective/urgent PCI procedures were enrolled in the Shinshu Prospective Multicenter Analysis for Elderly Patients with Coronary Artery Disease Undergoing Percutaneous Coronary Intervention registry. The primary end point was major adverse cardiovascular events (MACEs; cardiovascular death, myocardial infarction, and stroke) at 1 year. The 1-year incidence of MACEs, cardiac death, and stroke was significantly higher in elderly patients than in nonelderly patients (12.4% vs 5.3%, P < .0001; 7.8% vs 2.2%, P < .0001; and 2.8% vs 1.3%, P = .033, respectively). However, no significant difference in elective PCI procedures was detected. In elderly patients, the incidence of cardiac death and target lesion revascularization was significantly lower for DES than for non-DES (2.7% vs 10.5%, P = .0001 and 4.1% vs 8.6%, P = .029, respectively). Conclusion: Although elderly patients had a significantly poorer prognosis than younger patients, the adverse events rate was comparable in those patients who underwent elective PCI in the second-generation DES era.

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