scholarly journals GW26-e2161 Optimal Cutoff of the Triglyceride to High-Density-Lipoprotein Cholesterol Ratio to Detect Cardiovascular Risk Factors Among Han Adults in Xinjiang

2015 ◽  
Vol 66 (16) ◽  
pp. C1 ◽  
Author(s):  
Huayin Li ◽  
Bangdang Chen ◽  
Yining Yang ◽  
Xiang Ma ◽  
Fen Liu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
High Density Lipoprotein ◽  
Cardiovascular Risk Factors ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Optimal Cutoff ◽  
Cholesterol Ratio ◽  
Han Adults

Comparison of the Diagnostic Value Between Triglyceride-Glucose Index and Triglyceride-to-High Density Lipoprotein Cholesterol Ratio in MAFLD Patients: A Retrospective Cross-Sectional Study

2022 ◽  
Author(s):  
Zhi Liu ◽  
He He ◽  
Yuzhao Dai ◽  
Shenling Liao ◽  
Zhenmei An ◽  
...  
Keyword(s):  
Risk Factors ◽  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cholesterol Ratio

Abstract Background The triglyceride and glucose index (TyG) and triglyceride-to-high density lipoprotein cholesterol ratio (TG/HDL-C) were found to be substitute markers of insulin resistance (IR). We aimed to compare the efficacy of the two indicators in the diagnosis of Metabolic-Associated Fatty Liver Disease (MAFLD), which was rarely covered in the literature, and to construct a novel disease diagnosis model.Methods A retrospective cross-sectional study was carried out in West China Hospital of Sichuan University and 229 people (97 MAFLD and 132 Non-MAFLD) were included. Biochemical indexes were collected and analyzed by logistic regression to screen out indicators that expressed differently in MAFLD patients and healthy controls and incorporate them into a diagnostic model. MAFLD was diagnosed by Ultrasound.Results After adjusting for age, gender and BMI, Serum ALT, AST, AST/ALT (A/A), FPG, Cys-C, URIC, TG, HDL-C, ALP, GGT, nonHDL-C, LDL-C/HDL-C, nonHDL-C/HDL-C, TG/HDL-C, TC/HDL-C, TyG and TyG-BMI were risk factors of MAFLD through binary logistics regression analysis. The odds ratio of TG/HDL-C and TyG were 5.387 (95%CI: 2.986-9,718) and 107.945 (95% CI: 25.824-451.222). In identifying MAFLD, TyG, TG/HDL-C and TG were found to be the most vital indexes by the random forest method and the area under the curve (AUC) of them are all greater than 0.9 respectively. In addition, the combination of gender, BMI, ALT, TG, HDL-C, TyG and TyG-BMI had a great diagnostic efficiency for MAFLD.Conclusions TyG and TG/HDL-C were potential risk factors for MAFLD and the former made a better performance in diagnosing MAFLD. The combination of gender, BMI, ALT, TG, HDL-C, TyG and TyG-BMI improved the diagnostic capability of MAFLD.

scholarly journals Identificação de risco cardiovascular pela razão triglicerídeo/HDL-colesterol em pacientes com doença renal crônica em hemodiálise

2017 ◽  
Vol 27 (3) ◽  
pp. 27369
Author(s):  
Luciana Leitão Moraes ◽  
Alinne Lorrany Gomes Dos Santos ◽  
Luciana Pereira Pinto Dias ◽  
Dyanara De Almeida Oliveira ◽  
Denise Mafra ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Cardiovascular Risk ◽  
Kidney Disease ◽  
Renal Disease ◽  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Chronic Renal Disease ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Cholesterol Ratio

***Identification of cardiovascular risk by triglyceride/HDL- cholesterol ratio in patients with chronic renal disease in hemodialysis***AIMS: To identify cardiovascular risk by triglyceride/high density lipoprotein cholesterol ratio (TG/HDL-c) and to verify its association with socio-demographic factors, clinical parameters and body mass index in patients with chronic renal disease on hemodialysis.METHODS: Cross-sectional study, in which patients with chronic kidney disease in hemodialysis were evaluated. A non-probability convenience sampling was used. Sociodemographic data were collected through a semi-structured questionnaire interview, and clinical and laboratory data were obtained from the medical records. For the identification of cardiovascular risk, the TG/HDL-c ratio was calculated from plasma triglycerides (mg/dL) and high density lipoprotein cholesterol (mg/dL). The cut-off point for TG/HDL-c considered to be indicative of cardiovascular risk was ≥3.8 mg/dL. For statistical analysis, the chi-square test was used, and the significance level was set at 5% (p <0.05).RESULTS: A total of 71 patients were evaluated, with a mean age of 49.9±13.2 years, being 28 women (50.1±13.2 years) and 43 men (49.7±13.2 years). Among the 71 patients, 31 (43.66%) had cardiovascular risk characterized by the TG/HDL-c ratio ≥3.8 mg/dL. In general, the profile of patients with and without cardiovascular risk was similar. However, in patients with cardiovascular risk there was a higher proportion of males (77.42%), while in those who did not have this risk, the female gender was more frequent (52.50%). This variable showed a significant difference between the groups with and without cardiovascular risk (p=0.011).CONCLUSIONS: In this sample of patients with chronic kidney disease on hemodialysis, the TG/HDL-c ratio identified a high cardiovascular risk index, which was significantly associated with males.

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