scholarly journals TCT-655 Derivation and Validation of a Luminal Diameter Correction Factor for Determination of Stent Sizing by Optical Coherence Tomography: An ILUMIEN III sub-study

2017 ◽  
Vol 70 (18) ◽  
pp. B287
Author(s):  
Evan Shlofmitz ◽  
Yasir Parviz ◽  
Richard Shlofmitz ◽  
Bjorn Redfors ◽  
Akiko Maehara ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Correction Factor ◽  
Optical Coherence ◽  
Luminal Diameter

scholarly journals TCT-297 External elastic lamina vs luminal diameter for determination of stent diameter by optical coherence tomography

2017 ◽  
Vol 70 (18) ◽  
pp. B121-B122
Author(s):  
Yasir Parviz ◽  
Evan Shlofmitz ◽  
Bjorn Redfors ◽  
Mitsuaki Matsumura ◽  
Akiko Maehara ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Luminal Diameter ◽  
Stent Diameter ◽  
Elastic Lamina

External elastic lamina vs. luminal diameter measurement for determining stent diameter by optical coherence tomography: an ILUMIEN III substudy

2020 ◽  
Author(s):  
Evan Shlofmitz ◽  
Allen Jeremias ◽  
Yasir Parviz ◽  
Keyvan Karimi Galougahi ◽  
Björn Redfors ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Correction Factor ◽  
Vessel Diameter ◽  
Optical Coherence ◽  
Diameter Measurement ◽  
Luminal Diameter ◽  
Stent Diameter ◽  
Vessel Diameter Measurement ◽  
Elastic Lamina ◽  
Selection Of

Abstract Aims Optical coherence tomography (OCT)-guided external elastic lamina (EEL)-based stent sizing is safe and as effective as intravascular ultrasound in achieving post-procedural lumen dimensions. However, when compared with automated lumen diameter (LD) measurements, this approach is time-consuming. We aimed to compare vessel diameter measurements and stent diameter selection using either of these approaches and examined whether applying a correction factor to automated LD measurements could result in selecting similar stent diameters to the EEL-based approach. Methods and results We retrospectively compared EEL-based measurements vs. automated LD in reference segments in 154 OCT acquisitions and derived a correction factor for stent sizing using the ratio of EEL to LD measurements. We then prospectively applied the correction factor in 119 OCT acquisitions. EEL could be adequately identified in 100 acquisitions (84%) at the distal reference to allow vessel diameter measurement. Vessel diameters were larger with EEL-based vs. LD measurements at both proximal (4.12 ± 0.74 vs. 3.14 ± 0.67 mm, P < 0.0001) and distal reference segments (3.34 ± 0.75 vs. 2.64 ± 0.65 mm, P < 0.0001). EEL-based downsizing led to selection of larger stents vs. an LD-based upsizing approach (3.33 ± 0.47 vs. 2.70 ± 0.44, P < 0.0001). Application of correction factors to LD [proximal 1.32 (IQR 1.23–1.37) and distal 1.25 (IQR 1.19–1.36)] resulted in discordance in stent sizing by >0.25 mm in 63% and potentially hazardous stent oversizing in 41% of cases. Conclusion EEL-based stent downsizing led to selection of larger stent diameters vs. LD upsizing. While applying a correction factor to automated LD measurements resulted in similar mean diameters to EEL-based measurements, this approach cannot be used clinically due to frequent and potentially hazardous stent over-sizing.

scholarly journals DETERMINATION OF FACTORS ASSOCIATED WITH PERIPAPILLARY RETINAL NERVE FIBER LAYER AND MACULAR THICKNESS USING OPTICAL COHERENCE TOMOGRAPHY

2021 ◽  
Vol 32 (6) ◽  
pp. 448-457
Author(s):  
Hadi Ostadimoghaddam ◽  
Neda Nakhjavanpour ◽  
Abolfazl Payandeh ◽  
Mohammad-Reza Mohammad-Reza Sedaghat ◽  
◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Macular Thickness ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Factors Associated ◽  
Retinal Nerve Fiber

Correlation analysis of fundus autofluorescence, spectral domain optical coherence tomography, and visual function in patients with diabetic macular oedema treated with intravitreal ziv-aflibercept

2019 ◽  
Vol 29 (3) ◽  
pp. 271-277 ◽  
Author(s):  
Sergio E Hernandez-Da Mota ◽  
Enrique A Roig Melo-Granados ◽  
Jans Fromow-Guerra ◽  
Francisco Bejar-Cornejo ◽  
Roberto Gallego-Pinazo ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Regression Analysis ◽  
Correlation Analysis ◽  
Visual Function ◽  
Macular Oedema ◽  
Fundus Autofluorescence ◽  
Diabetic Macular Oedema ◽  
Optical Coherence ◽  
Average Thickness

Purpose: The aim of this study was to evaluate the correlations between fundus autofluorescence and morphologic parameters as well as visual function in patients with diabetic macular oedema treated with intravitreal ziv-aflibercept. Methods: A total of 34 eyes of 20 patients with untreated diabetic macular oedema received an intravitreal injection of ziv-aflibercept at baseline, and 1 and 2 months later. The baseline, 1-month, and two-month best corrected visual acuity determination, contrast sensitivity, spectral domain optical coherence tomography, mean central macular thickness, mean macular cube volume, mean macular cube average thickness, and fundus autofluorescence (decreased, normal, or increased; and single or multiple spots) were measured. Correlation analysis with a determination of Spearman’s rank correlation coefficient, regression analysis, agreement between investigators, and Friedman’s test were used for statistical analyses. Results: A direct correlation was observed between baseline fundus autofluorescence and macular cube average thickness at 1 month (r = 0.51, p = 0.020) and between fundus autofluorescence at 1 month and baseline macular cube average thickness (r = 0.50, p = 0.021). Regression analysis showed a coefficient of determination of 0.29 (p = 0.016) between baseline fundus autofluorescence and macular cube average thickness at 1 month. Conclusion: In patients with diabetic macular oedema, the pretreatment baseline degree of foveal fundus autofluorescence might be helpful in predicting macular cube average thickness in patients undergoing treatment with intravitreal ziv-aflibercept in the short term.

scholarly journals Comparison of Fourier-Domain and Time-Domain Optical Coherence Tomography in the Measurement of Thinnest Corneal Thickness in Keratoconus

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Chunxiao Wang ◽  
Xueying Xia ◽  
Bishan Tian ◽  
Shiyou Zhou
Keyword(s):  
Optical Coherence Tomography ◽  
Time Domain ◽  
Pearson Correlation ◽  
Corneal Thickness ◽  
Intraclass Correlation ◽  
Fourier Domain ◽  
Optical Coherence ◽  
Highly Correlated ◽  
Time Domain Oct

Objective. To compare fourier-domain optical coherence tomography (FD-OCT) and time-domain OCT (TD-OCT) in the determination of thinnest corneal thickness (TCT).Methods. This study included 55 keratoconus patients and 50 healthy volunteers. The RTVue-OCT (FD-OCT) and Visante-OCT (TD-OCT) were used for the measurement of the TCT. Three consecutive scans were performed. The comparison and agreement between the two modalities were analyzed by pairedt-test, the Pearson correlation, intraclass correlation coefficient (ICC), and Bland-Altman plots. intraobserver repeatability was analyzed by the intraobserver within-subject standard deviation (S(w)), coefficient of variation (CV(w)), and ICC.Results. The TCT value of normal corneas was higher by RTVue-OCT (530.4 ± 19.7 μm) than Visante-OCT (521.5 ± 18.3 μm) (p<0.001). For keratoconus eyes, the TCT was 425.0 ± 58.2 μm and 424.4 ± 55.7 μm (difference being 0.6 ± 10.2 μm,p=0.604). Strong correlation (r= 0.938∼0.985) (ICC = 0.915–0.984) was observed between the two OCTs, and each OCT exhibited excellent repeatability in determining the TCT in all subjects (ICC = 0.984–0.994).Conclusions. The values of TCT obtained from RTVue-OCT and Visante-OCT were highly correlated; however, the two values were different. Both OCT instruments exhibited good intraobserver reliability. The existence of systematic differences suggested that the two instruments cannot be used interchangeably.

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