Advanced Therapies for Ventricular Arrhythmias in Patients With Chagasic Cardiomyopathy

2021 ◽  
Vol 77 (9) ◽  
pp. 1225-1242
Author(s):  
Jorge Romero ◽  
Alejandro Velasco ◽  
Cristiano F. Pisani ◽  
Isabella Alviz ◽  
David Briceno ◽  
...  
1995 ◽  
Vol 113 (2) ◽  
pp. 858-861 ◽  
Author(s):  
Angelo Amato V. de Paola ◽  
Fernando Antonio Aquino Gondin ◽  
Vanderlei Hara ◽  
Alayde Mendonça

There are no controlled clinical trials evaluating drug therapy in patients with ventricular arrhythmias and chronic chagasic cardiomyopathy. Empirical treatment with disopyramide (400-1,000mg/d), phenytoin (4-6mg/d), mexiletine (600-1,200mg/d), propafenone (900mg/d), amiodarone ( loading: 1,000mg/d, 10-14 days; maintenance 200-600mg/d), and sotalol (320mg/d) had efficacy and tolerance ranging from 18% to 90% with heterogeneous criteria for efficacy definition. Further studies with homogenous criteria are required to determine which is the most appropriate drug therapy for patients with chronic chagasic cardiomyopathy and ventricular arrhythmias.


Heart ◽  
1995 ◽  
Vol 74 (3) ◽  
pp. 293-295 ◽  
Author(s):  
A. A. de Paola ◽  
J. A. Gomes ◽  
A. B. Terzian ◽  
M. H. Miyamoto ◽  
E. E. Martinez Fo

2007 ◽  
Vol 6 (1) ◽  
pp. 155-156
Author(s):  
J MARQUES ◽  
A KANSKY ◽  
I MENDOZA ◽  
L LOPEZGOMEZ ◽  
F MOLEIRO ◽  
...  

JAMA ◽  
1982 ◽  
Vol 247 (5) ◽  
pp. 581
Author(s):  
John K. Vyden

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