Prevalence and incidence of perinatal depression and depressive symptoms among Mexican women

2015 ◽  
Vol 175 ◽  
pp. 18-24 ◽  
Author(s):  
M. Asunción Lara ◽  
Laura Navarrete ◽  
Lourdes Nieto ◽  
Juan Pablo Barba Martín ◽  
José Luis Navarro ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Perinatal Depression ◽  
Mexican Women

scholarly journals Evidence for oestrogen sensitivity in perinatal depression: pharmacological sex hormone manipulation study

2018 ◽  
Vol 215 (3) ◽  
pp. 519-527 ◽  
Author(s):  
Divya Mehta ◽  
Monika Rex-Haffner ◽  
Helle Bach Søndergaard ◽  
Anja Pinborg ◽  
Elisabeth B. Binder ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dna Methylation ◽  
Depressive Symptoms ◽  
Perinatal Depression ◽  
Sex Hormone ◽  
Sex Steroid ◽  
Mood Changes ◽  
Induced Mood ◽  
Pharmacological Model

BackgroundEnhanced sensitivity to oestrogen signalling may drive increased risk for depressive symptoms when exposed to peripartum sex-steroid hormone fluctuations.AimTesting if 116 pre-identified sex steroid-responsive transcripts that predicted perinatal depression (PND) translates to a pharmacological model of hormone-induced mood changes.MethodWe generated longitudinal, genome-wide gene-expression and DNA-methylation data from 60 women exposed to a gonadotrophin-releasing hormone agonist (GnRHa) or placebo. We used linear mixed-effect models to assess differences between baseline and follow-up for gene expression and DNA methylation in the biphasic ovarian response to GnRHa.ResultsOf the 116 PND-predictive transcripts, a significant (19%) overlap was observed with those differentially expressed post-GnRHa at both early and later follow-up, indicating sustained effects. Similarly, 49% of tested genes were differentially methylated post-GnRHa at the late follow-up. Within the GnRHa group, a large proportion of PND genes were significantly associated (gene expression; DNA methylation) with changes in depressive symptoms (28%; 66%), oestradiol levels (49%; 66%) and neocortex serotonin transporter binding (8%; 45%) between baseline and follow-up.ConclusionsOur data bridge clinical PND biomarkers with a pharmacological model of sex hormone-induced mood changes and directly relate oestrogen-induced biological changes with depressive symptoms and associated serotonin-signalling changes. Our data highlight that individual variations in molecular sensitivity to oestrogen associate with susceptibility to hormone-induced mood changes and hold promise for candidate biomarkers.Declaration of interestV.G.F. received honorarium for being a speaker for H. Lundbeck A/S. E.B.B. receives research funding from Böhringer Ingelheim to investigate FKBP5 as a potential drug target for depression.

scholarly journals Depression across pregnancy and the postpartum, antidepressant use and the association with female sexual function

2018 ◽  
Vol 49 (09) ◽  
pp. 1490-1499 ◽  
Author(s):  
Megan Galbally ◽  
Stuart J. Watson ◽  
Michael Permezel ◽  
Andrew J. Lewis
Keyword(s):  
Depressive Symptoms ◽  
Childhood Trauma ◽  
Sexual Functioning ◽  
Perinatal Depression ◽  
Mode Of Delivery ◽  
Depression Scale ◽  
Partner Support ◽  
Antidepressant Use ◽  
Female Sexual Functioning ◽  
The Impact

AbstractBackgroundThere is an established relationship between depression and sexual functioning in women. However, there is limited research examining the relationship between perinatal depression and sexual functioning.MethodsThis study draws on the Mercy Pregnancy and Emotional Wellbeing Study and reports on 211 women recruited in early pregnancy and followed to 12 months postpartum. Women were assessed for depression using the Structured Clinical Interview for the DSM-IV, repeated measurement of depressive symptoms using the Edinburgh Postnatal Depression Scale and sexual functioning using the Female Sexual Functioning Inventory. Data were also collected on antidepressant use, mode of delivery, history of childhood trauma, breastfeeding and partner support.ResultsWomen showed a decline in sexual functioning over pregnancy and the first 6 months postpartum, which recovered by 12 months. For women with depression, sexual functioning was lower throughout pregnancy and continued to be lower at 6 months postpartum than those without depression. Ongoing depressive symptoms at 12 months were also associated with lower sexual functioning. Sexual functioning was not predicted by mode of delivery, antidepressant use or childhood trauma. Breastfeeding predicted lower sexual functioning only at 6 months. Higher partner support predicted higher female sexual functioning.ConclusionsPregnancy and the postpartum are a time of reduced sexual functioning for women; however, women with depression are more likely to have lower levels of sexual functioning and this was not predicted by antidepressant use. In women with perinatal depression, consideration of the impact on sexual functioning should be an integral part of care.

scholarly journals mHealth and Perinatal Depression in Low-and Middle-Income Countries: A Scoping Review of the Literature

2020 ◽  
Vol 17 (20) ◽  
pp. 7679
Author(s):  
Aliyah Dosani ◽  
Harshmeet Arora ◽  
Sahil Mazmudar
Keyword(s):  
Depressive Symptoms ◽  
Mobile Phone ◽  
Scoping Review ◽  
Perinatal Depression ◽  
Review Of The Literature ◽  
Middle Income ◽  
Middle Income Countries ◽  
Mobile Phone Applications ◽  
Perinatal Depressive Symptoms ◽  
Low And Middle Income

Women in low- and middle-income countries have high rates of perinatal depression. As smartphones become increasingly accessible around the world, there is an opportunity to explore innovative mHealth tools for the prevention, screening, and management of perinatal depression. We completed a scoping review of the literature pertaining to the use of mobile phone technologies for perinatal depression in low-and middle-income countries. PubMed CINHAL, and Google Scholar databases were searched, generating 423 results. 12 articles met our inclusion criteria. Two of the 12 articles reviewed mobile phone applications. The remaining 9 articles were study protocols or descriptive/intervention studies. Our results reveal that minimal literature is currently available on the use of mobile health for perinatal depression in low- and middle-income countries. We found four articles that present the results of an intervention that were delivered through mobile phones for the treatment of perinatal depressive symptoms and an additional qualitative study describing the perceptions of mothers receiving cognitive behavioral therapy via telephones. These studies demonstrated that depressive symptoms improved after the interventions. There is potential to improve the quality of mHealth interventions, specifically mobile phone applications for perinatal depressive symptoms and depression, through meaningful collaborative work between healthcare professionals and application developers.

Infant EEG and temperament negative affectivity: Coherence of vulnerabilities to mothers' perinatal depression

2016 ◽  
Vol 28 (4pt1) ◽  
pp. 895-911 ◽  
Author(s):  
Cara M. Lusby ◽  
Sherryl H. Goodman ◽  
Ellen W. Yeung ◽  
Martha Ann Bell ◽  
Zachary N. Stowe
Keyword(s):  
Depressive Symptoms ◽  
Perinatal Depression ◽  
Depressive Symptomatology ◽  
Negative Affectivity ◽  
Positive Association ◽  
Negative Association ◽  
Postnatal Exposure ◽  
Eeg Asymmetry ◽  
Frontal Eeg Asymmetry ◽  
Postnatal Depressive Symptoms

AbstractAssociations between infants' frontal EEG asymmetry and temperamental negative affectivity (NA) across infants' first year of life and the potential moderating role of maternal prenatal depressive symptoms were examined prospectively in infants (n = 242) of mothers at elevated risk for perinatal depression. In predicting EEG, in the context of high prenatal depressive symptoms, infant NA and frontal EEG asymmetry were negatively associated at 3 months of age and positively associated by 12 months of age. By contrast, for low depression mothers, infant NA and EEG were not significantly associated at any age. Postnatal depressive symptoms did not add significantly to the models. Dose of infants' exposure to maternal depression mattered: infants exposed either pre- or postnatally shifted from a positive association at 3 months to a negative association at 12 months; those exposed both pre- and postnatally shifted from a negative association at 3 months to a positive association at 12 months. Prenatal relative to postnatal exposure did not matter for patterns of association between NA and EEG. The findings highlight the importance of exploring how vulnerabilities at two levels of analysis, behavioral and psychophysiological, co-occur over the course of infancy and in the context of mothers' depressive symptomatology.

scholarly journals Vital Signs: Postpartum Depressive Symptoms and Provider Discussions About Perinatal Depression — United States, 2018

2020 ◽  
Vol 69 (19) ◽  
pp. 575-581 ◽  
Author(s):  
Brenda L. Bauman ◽  
Jean Y. Ko ◽  
Shanna Cox ◽  
Denise V. D’Angelo, MPH ◽  
Lee Warner ◽  
...  
Keyword(s):  
United States ◽  
Depressive Symptoms ◽  
Perinatal Depression ◽  
Vital Signs ◽  
Postpartum Depressive Symptoms

scholarly journals Fetal sex and maternal postpartum depressive symptoms: findings from two prospective pregnancy cohorts

2020 ◽  
Author(s):  
Whitney Cowell ◽  
Elena Colicino ◽  
Talia Askowitz ◽  
Farida Nentin ◽  
Rosalind Wright
Keyword(s):  
Depressive Symptoms ◽  
Perinatal Depression ◽  
Statistical Significance ◽  
Depression Scale ◽  
Postnatal Period ◽  
Maternal Depressive Symptoms ◽  
Fetal Sex ◽  
Female Fetus ◽  
Postpartum Depressive Symptoms ◽  
Core Set

Abstract Background: Fetal sex is known to modify the course and complications of pregnancy, with recent evidence of sex-differential fetal influences on the maternal immune and endocrine systems. In turn, heightened inflammation and surges in reproductive hormone levels associated with pregnancy and parturition have been linked with the development of perinatal depression. Here, we examined whether there is an association between fetal sex and maternal depression assessed during the prenatal and postnatal periods.Methods: The study included two multi-ethnic, prospective pregnancy cohorts that enrolled women from prenatal clinics in the Northeastern United States between 2001 and 2018. Maternal depressive symptoms were measured during the prenatal and postnatal periods using the Edinburgh Postpartum Depression Scale (EPDS) and newborn sex was reported by the mother following delivery. We used logistic regression to examine associations between fetal sex and maternal depressive symptoms (EPDS>10) during the prenatal period only, postnatal period only, or both periods versus no depressive symptoms during either period. We considered both unadjusted models and models adjusted for a core set of sociodemographic and lifestyle variables.Results: In adjusted models using PRISM data (N=528), women pregnant with a male versus female fetus had significantly greater odds of depressive symptoms during the postnatal period compared to women without depressive symptoms during either period (odds ratio [OR] = 5.24, 95% confidence interval [CI] = 1.93, 14.21). The direction of results was consistent in the ACCESS cohort, although the findings did not reach statistical significance (OR = 2.05, 95% CI = 0.86, 4.93). Significant associations were not observed in either cohort among women with prenatal symptoms only or women with prenatal and postnatal symptoms.Conclusions: Male fetal sex was associated with the onset of depressive symptoms during the postnatal period.

scholarly journals Fetal sex and maternal postpartum depressive symptoms: findings from two prospective pregnancy cohorts

2020 ◽  
Author(s):  
Whitney Cowell ◽  
Elena Colicino ◽  
Talia Askowitz ◽  
Farida Nentin ◽  
Rosalind Wright
Keyword(s):  
Depressive Symptoms ◽  
Perinatal Depression ◽  
Statistical Significance ◽  
Depression Scale ◽  
Postnatal Period ◽  
Maternal Depressive Symptoms ◽  
Fetal Sex ◽  
Female Fetus ◽  
Postpartum Depressive Symptoms ◽  
Core Set

Abstract Background: Fetal sex is known to modify the course and complications of pregnancy, with recent evidence of sex-differential fetal influences on the maternal immune and endocrine systems. In turn, heightened inflammation and surges in reproductive hormone levels associated with pregnancy and parturition have been linked with the development of perinatal depression. Here, we examined whether there is an association between fetal sex and maternal depression assessed during the prenatal and postnatal periods. Methods: The study included two multi-ethnic, prospective pregnancy cohorts that enrolled women from prenatal clinics in the Northeastern United States between 2001 and 2018. Maternal depressive symptoms were measured during the prenatal and postnatal periods using the Edinburgh Postpartum Depression Scale (EPDS) and newborn sex was reported by the mother following delivery. We used logistic regression to examine associations between fetal sex and maternal depressive symptoms (EPDS>10) during the prenatal period only, postnatal period only, or both periods versus no depressive symptoms during either period. We considered both unadjusted models and models adjusted for a core set of sociodemographic and lifestyle variables. Results: In adjusted models using PRISM data (N=528), women pregnant with a male versus female fetus had significantly greater odds of depressive symptoms during the postnatal period compared to women without depressive symptoms during either period (odds ratio [OR] = 5.24, 95% confidence interval [CI] = 1.93, 14.21). The direction of results was consistent in the ACCESS cohort, although the findings did not reach statistical significance (OR = 2.05, 95% CI = 0.86, 4.93). Significant associations were not observed in either cohort among women with prenatal symptoms only or women with prenatal and postnatal symptoms. Conclusions: Male fetal sex was associated with the onset of depressive symptoms during the postnatal period.

Sign in / Sign up

Export Citation Format

Share Document