Does Mycoplasma Genitalium Infection Predict Future Sexually Transmitted Infections in Female Urban Adolescents and Young Adults?

2018 ◽  
Vol 62 (2) ◽  
pp. S82
Author(s):  
Jocelyn Ronda ◽  
Charlotte Gaydos ◽  
Jamie Perin ◽  
Lisa Tabacco ◽  
Jenell Coleman ◽  
...  
Keyword(s):  
Young Adults ◽  
Sexually Transmitted Infections ◽  
Urban Adolescents ◽  
Mycoplasma Genitalium ◽  
Adolescents And Young Adults ◽  
Sexually Transmitted

scholarly journals Partner notification and treatment outcomes among South African adolescents and young adults diagnosed with a sexually transmitted infection via laboratory-based screening

2020 ◽  
Vol 31 (7) ◽  
pp. 627-636 ◽  
Author(s):  
Pooja Chitneni ◽  
Mags Beksinska ◽  
Janan J Dietrich ◽  
Manjeetha Jaggernath ◽  
Kalysha Closson ◽  
...  
Keyword(s):  
Young Adults ◽  
Sexually Transmitted Infection ◽  
Trichomonas Vaginalis ◽  
Partner Notification ◽  
Mycoplasma Genitalium ◽  
Adolescents And Young Adults ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Care Cascade ◽  
Essential Components

Partner notification and treatment are essential components of sexually transmitted infection (STI) management, but little is known about such practices among adolescents and young adults. Using data from a prospective cohort study (AYAZAZI) of youth aged 16–24 years in Durban, South Africa, we assessed the STI care cascade across participant diagnosis, STI treatment, partner notification, and partner treatment; index recurrent STI and associated factors; and reasons for not notifying partner of STI. Participants completed laboratory-based STI screening ( Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Trichomonas vaginalis) at enrollment and at 12 months. Of the 37/216 participants with STI (17%), 27/37 (73%) were women and 10/37 (27%) were men. Median age was 19 years (IQR: 18–20). Of the participants with STI, 23/37 (62%) completed a Treatment and Partner Tracing Survey within 6 months of diagnosis. All survey participants reported completing STI treatment (100%), 17/23 (74%) notified a partner, and 6/23 (35%) reported partner treatment. Overall, 4/23 (11%) participants had 12-month recurrent C. trachomatis infection, with no association with partner notification or treatment. Stigma and lack of STI knowledge were reasons for not notifying partner of STI. STI partner notification and treatment is a challenge among youth. Novel strategies are needed to overcome barriers along the STI care cascade.

scholarly journals The Risk of Sexually Transmitted Infections Following First-Episode Schizophrenia Among Adolescents and Young Adults: A Cohort Study of 220 545 Subjects

2020 ◽  
Vol 46 (4) ◽  
pp. 795-803 ◽  
Author(s):  
Chih-Sung Liang ◽  
Ya-Mei Bai ◽  
Ju-Wei Hsu ◽  
Kai-Lin Huang ◽  
Nai-Ying Ko ◽  
...  
Keyword(s):  
Young Adults ◽  
Young People ◽  
Sexually Transmitted Infections ◽  
Adolescents And Young Adults ◽  
First Episode ◽  
Antipsychotic Treatment ◽  
Research Database ◽  
Cox Regression Analysis ◽  
Sexually Transmitted ◽  
First Episode Schizophrenia

Abstract Young people are disproportionately affected by sexually transmitted infections (STIs). The risk of STIs in young people following first-episode schizophrenia is unknown. This study using Taiwan’s National Health Insurance Research Database enrolled 44 109 adolescents and young adults with first-episode schizophrenia and 176 436 age- and sex-matched controls without schizophrenia from 2001 through 2009 and followed to the end of 2011. New-onset STIs were identified. Survival analysis was performed. Cox regression analysis was used to examine the effects of comorbid substance use disorder (SUD), schizophrenia medications, and schizophrenia severity. The E value for causality of evidence was calculated. We found that young people had a higher risk of STIs following first-episode schizophrenia compared with controls without schizophrenia (hazard ratio [HR] = 2.35, 95% CI = 2.08–2.64); these STIs included human immunodeficiency virus (HIV) (3.70, 2.60–5.28) and syphilis (5.35, 3.96–7.23). They also showed a disproportionate distribution of STIs, with an increased proportion of syphilis (20.4% vs 8.2%) and HIV (9.1% vs 6.0%). When presenting with SUD, the risks of HIV (11.00, 7.02–17.25) and syphilis (9.11, 6.16–13.47) were further increased. The severe schizophrenia group had an extremely high risk of syphilis (41.26, 27.69–61.47) and HIV (7.50, 3.85–14.62). Schizophrenia medications may provide beneficial effects against contracting STIs (0.77, 0.68–0.89). We concluded that following first-episode schizophrenia, young patients are at higher risk of STIs, particularly HIV and syphilis. The risk further increased when subjects presented with SUD or severe schizophrenia. Importantly, antipsychotic treatment may lower the risk of STIs.

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