Young Age at First Sexual Intercourse and Sexually Transmitted Infections in Adolescents and Young Adults

Abstract Background and aims: Condom use at sexual debut is associated with subsequent condom use and with decreased risk of sexually transmitted infections. There is a dearth of data on determinants of condom use at first sexual intercourse. We aimed to determine factors associated with condom use at first sexual intercourse before marriage among Vietnamese adolescents and youths. Methods: The study involved the analysis of data from the Survey Assessment of Vietnamese Youth, 2003, the first nationally representative survey of young people in Vietnam. The survey included 7584 adolescents and youths aged 14–25 years. In this study, data of 605 adolescents and youths who had engaged in premarital sex were analyzed for factors associated with condom use using descriptive analyses, and regression techniques, allowing for sampling weights, clustering and stratification. Results: Of 605 adolescents and youths who had engaged in premarital sex, 28.6% reported condom use at first sexual intercourse. Condom use at sexual debut was less common in females than males [odds ratio (OR)=0.15; 95% confidence interval (95% CI)=0.07–0.30] and less common in those who experienced peer pressure to engage in social higher risk behaviors (OR=0.57; 95% CI=0.32–0.99). Condom use was more common if a friend/acquaintance or a stranger/sex worker was the first sexual partner (OR=2.20; 95% CI=1.16–4.17 and OR=17.90; 95% CI=6.88–46.54) respectively, each compared with fiancé/boyfriend/girlfriend as first sexual partner. Conclusions: These data suggest that approximately one in three unmarried Vietnamese youths used a condom at first sexual intercourse. Gender, peer pressure and the nature of the relationship to the first sexual partner were independently associated with condom use. These results can inform programs directed at preventing HIV and other sexually transmitted infections among young Vietnamese.

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The Risk of Sexually Transmitted Infections Following First-Episode Schizophrenia Among Adolescents and Young Adults: A Cohort Study of 220 545 Subjects

Schizophrenia Bulletin ◽

10.1093/schbul/sbz126 ◽

2020 ◽

Vol 46 (4) ◽

pp. 795-803 ◽

Cited By ~ 1

Author(s):

Chih-Sung Liang ◽

Ya-Mei Bai ◽

Ju-Wei Hsu ◽

Kai-Lin Huang ◽

Nai-Ying Ko ◽

...

Keyword(s):

Young Adults ◽

Young People ◽

Sexually Transmitted Infections ◽

Adolescents And Young Adults ◽

First Episode ◽

Antipsychotic Treatment ◽

Research Database ◽

Cox Regression Analysis ◽

Sexually Transmitted ◽

First Episode Schizophrenia

Abstract Young people are disproportionately affected by sexually transmitted infections (STIs). The risk of STIs in young people following first-episode schizophrenia is unknown. This study using Taiwan’s National Health Insurance Research Database enrolled 44 109 adolescents and young adults with first-episode schizophrenia and 176 436 age- and sex-matched controls without schizophrenia from 2001 through 2009 and followed to the end of 2011. New-onset STIs were identified. Survival analysis was performed. Cox regression analysis was used to examine the effects of comorbid substance use disorder (SUD), schizophrenia medications, and schizophrenia severity. The E value for causality of evidence was calculated. We found that young people had a higher risk of STIs following first-episode schizophrenia compared with controls without schizophrenia (hazard ratio [HR] = 2.35, 95% CI = 2.08–2.64); these STIs included human immunodeficiency virus (HIV) (3.70, 2.60–5.28) and syphilis (5.35, 3.96–7.23). They also showed a disproportionate distribution of STIs, with an increased proportion of syphilis (20.4% vs 8.2%) and HIV (9.1% vs 6.0%). When presenting with SUD, the risks of HIV (11.00, 7.02–17.25) and syphilis (9.11, 6.16–13.47) were further increased. The severe schizophrenia group had an extremely high risk of syphilis (41.26, 27.69–61.47) and HIV (7.50, 3.85–14.62). Schizophrenia medications may provide beneficial effects against contracting STIs (0.77, 0.68–0.89). We concluded that following first-episode schizophrenia, young patients are at higher risk of STIs, particularly HIV and syphilis. The risk further increased when subjects presented with SUD or severe schizophrenia. Importantly, antipsychotic treatment may lower the risk of STIs.

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Screening for Nonviral Sexually Transmitted Infections in Adolescents and Young Adults

10.1542/9781610021494-part05-screening_for_nonvir ◽

2018 ◽

pp. 1298-1298

Keyword(s):

Young Adults ◽

Sexually Transmitted Infections ◽

Adolescents And Young Adults ◽

Sexually Transmitted

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Point-of-Care Testing to Guide Treatment and Estimate Risk Factors for Sexually Transmitted Infections in Adolescents and Young People With Human Immunodeficiency Virus in Eswatini

Open Forum Infectious Diseases ◽

10.1093/ofid/ofaa052 ◽

2020 ◽

Vol 7 (3) ◽

Cited By ~ 1

Author(s):

Caitlyn L Jasumback ◽

Sarah H Perry ◽

Tara E Ness ◽

Martha Matsenjwa ◽

Zandile T Masangane ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Young Adults ◽

Sexually Transmitted Infections ◽

Sexual Partner ◽

Adolescents And Young Adults ◽

World Health ◽

Sexually Active ◽

Sexually Transmitted ◽

Life Years ◽

Immunodeficiency Virus

Abstract Background The World Health Organization (WHO) estimates 127 million new cases of Chlamydia trachomatis (CT), 87 million new cases of Neisseria gonorrhea (NG), and 156 million new cases of Trichomonas vaginalis (TV) each year, which corresponds to 355 (219–606), 303 (216–468), and 243 (97.6–425) thousand disability-adjusted life-years. In low-resource settings, however, sexually transmitted infections (STIs) are treated syndromically and many individuals with asymptomatic infection may be missed, especially adolescents and young adults with human immunodeficiency virus (HIV). Methods We enrolled patients aged 15–24 with HIV (N = 300) attending a family-centered HIV clinic in Mbabane, Eswatini. Participants completed a sexual history questionnaire and provided urine as well as oropharyngeal and/or vaginal swabs, if sexually active, for testing with Xpert CT/NG and TV tests. Analysis included bivariate and multivariate odds ratios and test sensitivity and specificity. Results Sexually transmitted infection rates were highest (25.0%; 95% confidence interval [CI], 15.2–37.3) in females ages 20–24 who were ever sexually active. In patients with confirmed STIs, NG (15 of 32, 47%) was more common than CT (9 of 32, 28%) and TV (8 of 32, 25%). Syndromic screening alone had a sensitivity of 32.0% (95% CI, 14.9–53.3) and specificity of 86.0% (95% CI, 79.0–91.4) but varied by gender. The presence of an STI was associated with reporting new sexual partner(s) (OR = 2.6; 95% CI, 1.1–6.4), sometimes to never using condoms (OR = 4.2; 95% CI, 1.7–10.2), most recent sexual partner >25 years old (OR = 3.2; 95% CI, 1.3–7.9), and HIV diagnosis at age ≥15 years (OR = 3.4; 95% CI, 1.4–8.2). Conclusions Syndromic screening alone performed poorly. Routine diagnostic testing significantly increases STI detection and should be considered in high-risk populations, such as adolescents and young adults with HIV.

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