scholarly journals United States national trends in prevalence of major depressive episode and co-occurring suicidal ideation and treatment resistance among adults

Author(s):  
Jennifer Voelker ◽  
Harsh Kuvadia ◽  
Qian Cai ◽  
Kun Wang ◽  
Ella Daly ◽  
...  
2019 ◽  
Vol 36 (2) ◽  
pp. 329-335
Author(s):  
Qian Cai ◽  
John J. Sheehan ◽  
Bingcao Wu ◽  
Larry Alphs ◽  
Nancy Connolly ◽  
...  

2010 ◽  
Vol 120 (1-3) ◽  
pp. 226-230 ◽  
Author(s):  
Emilie Olié ◽  
Sébastien Guillaume ◽  
Isabelle Jaussent ◽  
Philippe Courtet ◽  
Fabrice Jollant

2011 ◽  
Vol 26 (S2) ◽  
pp. 1641-1641
Author(s):  
J. Rochette ◽  
P. Polo ◽  
M. Pacaut-Troncin ◽  
P.J.-L. Terra

During a major depressive episode, suicidal risks are increased and the possibility of request of help and treatment is conditionedby the way the subject structured its attachment in the childhood. We present a study which concerns the detailed examination, during 6 months, mental states of 40 patients presenting a major depressive episode and frequenting a Medical psychological Center connected with a Psychiatric hospital. The collection of the data is made with tools stemming from various fields (DSM4, theory of the attachment, the psychoanalytical psychology)“.The population is divided to three Camire profiles (Pierre Humbert et al, 1996) (Secure, Preoccupied, Avoidant). We chose 3 markers which can inform us about the evolution of the crisis according to the profile of attachment :1-Intensity of the suicidal idéation « SSI » (Beck et all.1979)2-therapeutic Alliance “WAI” Horvath et Greenberg, 1989)3-Intensité of the depression. (Hamilton HAMD-21)HypothesisThe attachment says “sécure” facilitate better scores in these 3 markers.Results1)The regulations emotional Secure does not protect against strong suicidal ideation in patients suffering from major depressive disorder. Freud's theory of trauma in this direction by assuming a tolerable threshold above which any topic is disorganized. (p-value = 0,05)2)The strategies of emotional regulation parts protect against suicidal thoughts while concerned about emotional regulation strategies to expose depressed suicidal subjects. (p-value = 0,09)3)According to the literature, we find a better alliance with secure attachment. (except at the beginning of care) (p-value = 0,06 at period T3 and p-value = 0,08 at period T6)


2011 ◽  
Vol 26 (S2) ◽  
pp. 2025-2025
Author(s):  
Z. Rihmer

Antidepressant-resistant major depression (AD-RD) is a great challenge for the treating clinician. The most widely accepted definition of AD-RD refers that the depressed patient does not show a clinically significant response after at least two adequate trials of different classes of antidepressants. In spite of the fact that there are several causes of AD-RD in general, there is increasing evidence that one of the most common sources of it is the unrecognized bipolar nature of the “unipolar” major depressive episode, when the patients receive antidepressant monotherapy - unprotected by mood stabilizers/atypical antipsychotics. While it is well documented that the optimal clinical response to antidepressants is much rare in bipolar I and II than in unipolar major depression, only the most recent clinical studies have focused on the boundaries between treatment-resistant unipolar major depressive disorder and bipolar disorder. The most widely noted conclusion of the prior studies on AD-RD is that if noncompliance, hypothyreosis, use of “depressiogenic” drugs and pharmacokinetic causes etc, can be excluded, antidepressant-resistance reflects the heterogeneity of depressive disorders and different subgroups of depressed patients respond (or do not respond) to different drugs. However, current psychopathological research on the complex relationship between unipolar depression and bipolar disorders show that the most common source of antidepressant-resistance in DSM-IV diagnosed unipolar major depression is the result of the subthreshold or unrecognized bipolar nature of the depressive episode and antidepressant-induced (hypo)manic switches, antidepressant-resistance and “suicide-inducing” potential of antidepressants seem to be related to the underlying bipolarity of the major depressive episode.


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