Facile green synthesis and characterization of Crataegus microphylla extract-capped silver nanoparticles (CME@Ag-NPs) and its potential antibacterial and anticancer activities against AGS and MCF-7 human cancer cells

2020 ◽  
Vol 820 ◽  
pp. 153186 ◽  
Author(s):  
Sobhan Mortazavi-Derazkola ◽  
Mohammad Ali Ebrahimzadeh ◽  
Omid Amiri ◽  
Hamid Reza Goli ◽  
Alireza Rafiei ◽  
...  
2019 ◽  
Vol 15 (8) ◽  
pp. 903-910 ◽  
Author(s):  
Piotr Świątek ◽  
Jolanta Saczko ◽  
Nina Rembiałkowska ◽  
Julita Kulbacka

Background: Hydrazine-hydrazones represent a group of bioactive compounds that display antibacterial, anti-inflammatory, antiviral or anticancer activities. Methods: The group of new derivatives was evaluated by the viability assay in human cancer and normal cells. Results: The dimethylpyridine hydrazones showed potent inhibition of cell proliferation of breast, colon cancer cells, human melanoma and glioblastoma. Compound 12 inhibited proliferation of cancer cells exhibiting a drug-resistant phenotype (MCF-7/DX and LoVoDX) at low millimolar concentrations. Whereas, antimelanoma activity was revealed by Compounds 2, 4, 7 and 12. Conclusion: The present results highlighted newly synthetized hydrazine derivatives an excellent base for the design of new anticancer agents and resistance inhibitors.


2002 ◽  
Vol 181 (1) ◽  
pp. 55-64 ◽  
Author(s):  
Erhard Bieberich ◽  
Bin Hu ◽  
Jeane Silva ◽  
Sarah MacKinnon ◽  
Robert K. Yu ◽  
...  

Author(s):  
Sajib Aninda Dhar ◽  
Rashedul Alam Chowdhury ◽  
Shaon Das ◽  
Md. Khalid Nahian ◽  
Dipa Islam ◽  
...  

2016 ◽  
Vol 6 (7) ◽  
pp. 1023-1029 ◽  
Author(s):  
Faria Zia ◽  
Nida Ghafoor ◽  
Mudassir Iqbal ◽  
Saliha Mehboob

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