Rośliny lecznicze występujące w południowej części Indii

Omówiono i opisano wybrane gatunki znajdujące się zarówno w stanie naturalnym, jak i w uprawie, spośród 7500 roślin leczniczych występujących na terenie Indii – prawdziwego emporium roślin leczniczych i aromatycznych. W codziennym użyciu są tam takie gatunki jak: Azadirachta indica, Cardiospermum halicacabum, Erythrina indica, Gloriosa superba, Jatropha curcas, Moringa oleifera, Phyllanthus amarus, Ssbania grandiflora, Tamarindus indica, Tridax procumbens i Vitex negundo. Najczęściej zaś uprawiane są: Aloe vera, Azadirachta indica, Curcuma longa, Emblica officinalis, Eukaliptus tereticornis, Gloriosa superba, Moringa oleifera, Ricinus communis, Sesamum indicum, Ssbania grandiflora, Solanum americanum, Tamarindus indica i Zingiber officinale. Określono też ich wartość użytkową.

Colchicine (a high-priced alkaloid) accumulation and HPTLC quantification in different stages of in vitro developed tuber of Gloriosa superba L.

Background Gloriosa superba L. belongs to Colchicaceae, which is an important medicinal plant containing high-priced alkaloid colchicines and other potent phytochemicals. Due to its extensive importance at the industrial level, this plant is overexploited. Moreover, indiscriminate harvesting for raw material leads to a decline in the population of this plant in the natural environment. Thus, the present study deals with the optimization of colchicine accumulation from the different intervals of in vitro and in vivo tubers of Gloriosa. Result To obtain in vitro tuberization, shoot tip explants were inoculated on Murashige and Skoog medium prepared with 3 mg/l BA and 0.5 mg/l Kn + 1 mg/l 2, 4-D followed by 2 mg/l BA + 0.2 mg/l NAA. In the high-performance thin-layer chromatography study (HPTLC), the linearity range of colchicine was set at a concentration range of 100–1000 ng/spot with a regression value (r) of 0.99. Its Rf value (0.25) was recorded at 254 nm. The colchicine amount in the in vivo tuber was 7.75 ± 0.25% dry weight, while the nearby amount of 7.7 ± 0.40% dry weight of colchicine was produced from 2 weeks in vitro old tuber. This value was followed by the 4th-week old tuber with 6.35 ± 0.17% dry weight and then a gradual decrease in its accumulation. Conclusion The significant results for the accumulation of colchicine at different stages were observed. Hence, this strategy of colchicine production creates a new possibility for improved production of colchicine under in vitro conditions which will be helpful to various pharmaceutical industries without damaging the plants from the natural environment. Graphical abstract

PHARMACOLOGICAL ASSESSMENT OF ANTIULCER ACTIVITY OF GLORIOSA SUPERBA LINN TUBERS IN EXPERIMENTALLY INDUCED GASTRIC ULCERS

In a study, the potential of hydroalcoholic and petroleum ether extract of Gloriosa superba Linn (GS) tubers in the mitigation of antisecretory and antiulcer was studied. Both extracts were tested at 100, 200, and 400 mg/kg/p.o. using ethanol, and cold stress as toxicants. Both the extracts showed significant ulcer protection at the highest dose of 400mg/kg as compared to standard drug lansoprazole. To support its antiulcer potential, the plant was examined for radical - scavenging capability by lipid peroxidation. The extracts showed a comparative significant result. The flavonoids & polyphenols in the extracts verify the antioxidant potential. From the results, it was concluded that both hydroalcoholic and petroleum ether extracts of tubers of Gloriosa superba are having gastric ulcer protective activity.