scholarly journals P2-358: Age-related changes of the brain white matter associated with electrophysiological and behavioral processing of visual motion

2011 ◽  
Vol 7 ◽  
pp. S428-S428
Author(s):  
Voyko Kavcic
Author(s):  
R. Kalpana ◽  
S. Muttan ◽  
B. Agrawala

Diffusion Tensor Magnetic Resonance Imaging (DTMRI) has proved useful for microstructure characterization of the brain. This technique also helps determining complex connectivity of fiber tracts. The brain white matter (BMW) changes with respect to age and corresponding appearance of white-matter lesions among the brain’s message-carrying axons affects cognitive functions in old age. In this paper, the observed morphology in BWM on ageing is analyzed using statistical parameters extracted from DTMR images of different age groups. The gray level co-occurrence matrix (GLCM) obtained from the segmented images gives 14 textural features, subsets of which are adopted as the input sets in a backpropagation neural network classifier. The network is trained to predict the age based on BMW details used as the inputs. The proposed method helps in understanding the age-related changes in white matter. This is useful for the physician in understanding miscorrelation in motor activities and relevant causes in elderly subjects.


Author(s):  
R. Kalpana ◽  
S. Muttan ◽  
B. Agrawala

Diffusion Tensor Magnetic Resonance Imaging (DTMRI) has proved useful for microstructure characterization of the brain. This technique also helps determining complex connectivity of fiber tracts. The brain white matter (BMW) changes with respect to age and corresponding appearance of white-matter lesions among the brain’s message-carrying axons affects cognitive functions in old age. In this paper, the observed morphology in BWM on ageing is analyzed using statistical parameters extracted from DTMR images of different age groups. The gray level co-occurrence matrix (GLCM) obtained from the segmented images gives 14 textural features, subsets of which are adopted as the input sets in a backpropagation neural network classifier. The network is trained to predict the age based on BMW details used as the inputs. The proposed method helps in understanding the age-related changes in white matter. This is useful for the physician in understanding miscorrelation in motor activities and relevant causes in elderly subjects.


NeuroImage ◽  
2009 ◽  
Vol 47 ◽  
pp. S128
Author(s):  
H Lemaitre ◽  
S Marenco ◽  
M Emery ◽  
T Alam ◽  
M Geramita ◽  
...  

1997 ◽  
Vol 93 (3) ◽  
pp. 233-240 ◽  
Author(s):  
M. Ueno ◽  
Ichiro Akiguchi ◽  
Masanori Hosokawa ◽  
Masahiko Shinnou ◽  
Haruhiko Sakamoto ◽  
...  

2018 ◽  
Vol 23 (7) ◽  
pp. 831-839 ◽  
Author(s):  
Yang-Teng Fan ◽  
Ya-Wen Fang ◽  
Ya-Ping Chen ◽  
Eric D. Leshikar ◽  
Ching-Po Lin ◽  
...  

2016 ◽  
Vol 5 (1) ◽  
pp. 30-38 ◽  
Author(s):  
Jennifer J. Heisz ◽  
Ana Kovacevic

Age-related changes in the brain can compromise cognitive function. However, in some cases, the brain is able to functionally reorganize to compensate for some of this loss. The present paper reviews the benefits of exercise on executive functions in older adults and discusses a potential mechanism through which exercise may change the way the brain processes information for better cognitive outcomes. Specifically, older adults who are more physically active demonstrate a shift toward local neural processing that is associated with better executive functions. We discuss the use of neural complexity as a sensitive measure of the neural network plasticity that is enhanced through exercise. We conclude by highlighting the future work needed to improve exercise prescriptions that help older adults maintain their cognitive and physical functions for longer into their lifespan.


1984 ◽  
Vol 100 (1) ◽  
pp. 19-23 ◽  
Author(s):  
J. Balthazart ◽  
M. Schumacher ◽  
G. Malacarne

ABSTRACT It has been suggested that testosterone is less effective at inducing crowing behaviour in young birds than in adults because of the presence of higher levels of steroid 5β-reductase in the young brain, which converts testosterone to inactive 5β-reduced metabolites. This hypothesis was tested indirectly by comparing the relative potencies of 5α-dihydrotestosterone (5α-DHT), which cannot be converted to 5β-metabolities, and testosterone at inducing crowing in young gonadectomized male and female quail. The promotion of cloacal gland growth by these treatments was also assessed since there are no age-related changes in 5β-reductase in this organ. Silicone elastomer implants (2·5, 5 and 10 mm) containing 5α-DHT were more effective at stimulating crowing than similar implants of testosterone whilst there was little difference in their potency at inducing cloacal gland growth. These results are consistent with the hypothesis that brain steroid 5β-reductase regulates the behavioural activity of testosterone in the brain of young birds. J. Endocr. (1984) 100, 19–23


Sign in / Sign up

Export Citation Format

Share Document