NEURON-TARGETED CAVEOLIN-1 GENE THERAPY PRESERVES COGNITIVE FUNCTION AND SYNAPTIC PLASTICITY IN A MOUSE MODEL OF ALZHEIMER’S DISEASE (AD)

Shanshan Wang; Joseph Leem; Mckenzie Fannon; Natalia Kleschevnikova; Brian Head

doi:10.1016/j.jalz.2019.06.061

NEURON-TARGETED CAVEOLIN-1 GENE THERAPY PRESERVES COGNITIVE FUNCTION AND SYNAPTIC PLASTICITY IN A MOUSE MODEL OF ALZHEIMER’S DISEASE (AD)

Alzheimer s & Dementia ◽

10.1016/j.jalz.2019.06.061 ◽

2019 ◽

Vol 15 (7) ◽

pp. P246-P248

Author(s):

Shanshan Wang ◽

Joseph Leem ◽

Mckenzie Fannon ◽

Natalia Kleschevnikova ◽

Brian Head

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Gene Therapy ◽

Synaptic Plasticity ◽

Cognitive Function ◽

Mouse Model ◽

Caveolin 1 ◽

Model Of Alzheimer’S Disease

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Neuron‐Targeted Caveolin‐1 Gene Therapy Preserves Cognitive Function and Synaptic Plasticity in a Mouse Model of Alzheimer's Disease (AD)

The FASEB Journal ◽

10.1096/fasebj.2019.33.1_supplement.737.6 ◽

2019 ◽

Vol 33 (S1) ◽

Author(s):

Joseph Leem ◽

Shanshan Wang ◽

Mehul Dhanani ◽

Alice Zemljic‐Harpf ◽

Isabella Kelly ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Gene Therapy ◽

Synaptic Plasticity ◽

Cognitive Function ◽

Mouse Model ◽

Caveolin 1 ◽

Model Of Alzheimer’S Disease

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Synapsin-caveolin-1 gene therapy preserves neuronal and synaptic morphology and prevents neurodegeneration in a mouse model of Alzheimer’s disease

Molecular Therapy — Methods & Clinical Development ◽

10.1016/j.omtm.2021.03.021 ◽

2021 ◽

Author(s):

Shanshan Wang ◽

Joseph S. Leem ◽

Sonia Podvin ◽

Vivian Hook ◽

Natalia Kleschevnikov ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Gene Therapy ◽

Mouse Model ◽

Caveolin 1 ◽

Model Of Alzheimer’S Disease

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Low-Frequency Repetitive Transcranial Magnetic Stimulation Ameliorates Cognitive Function and Synaptic Plasticity in APP23/PS45 Mouse Model of Alzheimer’s Disease

Frontiers in Aging Neuroscience ◽

10.3389/fnagi.2017.00292 ◽

2017 ◽

Vol 9 ◽

Cited By ~ 9

Author(s):

Zhilin Huang ◽

Tao Tan ◽

Yehong Du ◽

Long Chen ◽

Min Fu ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Synaptic Plasticity ◽

Cognitive Function ◽

Transcranial Magnetic Stimulation ◽

Mouse Model ◽

Magnetic Stimulation ◽

Repetitive Transcranial Magnetic Stimulation ◽

Low Frequency ◽

Model Of Alzheimer’S Disease

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Combination of docosahexaenoic acid and Ginko biloba extract improves cognitive function and hippocampal tissue damages in a mouse model of Alzheimer’s disease

Journal of Chemical Neuroanatomy ◽

10.1016/j.jchemneu.2021.101995 ◽

2021 ◽

pp. 101995

Author(s):

Nabila E. Abdelmeguid ◽

Mahmoud I.M. Khalil ◽

Rasha Elhabet ◽

Ahmed S. Sultan ◽

Sherine Abdel Salam

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Function ◽

Docosahexaenoic Acid ◽

Mouse Model ◽

Hippocampal Tissue ◽

Model Of Alzheimer’S Disease ◽

Tissue Damages ◽

Ginko Biloba

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Inhibition of 2-Arachidonoylglycerol Metabolism Alleviates Neuropathology and Improves Cognitive Function in a Tau Mouse Model of Alzheimer’s Disease

Molecular Neurobiology ◽

10.1007/s12035-021-02400-2 ◽

2021 ◽

Author(s):

Jack Hashem ◽

Mei Hu ◽

Jian Zhang ◽

Fei Gao ◽

Chu Chen

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Function ◽

Mouse Model ◽

Model Of Alzheimer’S Disease ◽

Tau Mouse Model

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Dysregulation of the mTOR Pathway Mediates Impairment of Synaptic Plasticity in a Mouse Model of Alzheimer's Disease

PLoS ONE ◽

10.1371/journal.pone.0012845 ◽

2010 ◽

Vol 5 (9) ◽

pp. e12845 ◽

Cited By ~ 127

Author(s):

Tao Ma ◽

Charles A. Hoeffer ◽

Estibaliz Capetillo-Zarate ◽

Fangmin Yu ◽

Helen Wong ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Synaptic Plasticity ◽

Mouse Model ◽

Mtor Pathway ◽

Model Of Alzheimer’S Disease

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Effect of transthyretin gene therapy in the 5XFAD mouse model of Alzheimer’s disease

Alzheimer s & Dementia ◽

10.1002/alz.040384 ◽

2020 ◽

Vol 16 (S9) ◽

Author(s):

Ana Rita Batista ◽

Paola Rodriguez ◽

Monique Otero ◽

Robert M. King ◽

Matthew J. Gounis ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Gene Therapy ◽

Mouse Model ◽

Model Of Alzheimer’S Disease ◽

5Xfad Mouse

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Disrupted-in-schizophrenia-1 protects synaptic plasticity in a transgenic mouse model of Alzheimer’s disease as a mitophagy receptor

Aging Cell ◽

10.1111/acel.12860 ◽

2018 ◽

Vol 18 (1) ◽

pp. e12860 ◽

Cited By ~ 18

Author(s):

Zhao-Tao Wang ◽

Mei-Hong Lu ◽

Yan Zhang ◽

Wen-Li Ji ◽

Lei Lei ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Synaptic Plasticity ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease

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AVP(4-8) Improves Cognitive Behaviors and Hippocampal Synaptic Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease

Neuroscience Bulletin ◽

10.1007/s12264-019-00434-0 ◽

2019 ◽

Vol 36 (3) ◽

pp. 254-262 ◽

Cited By ~ 2

Author(s):

Xiumin Zhang ◽

Fang Zhao ◽

Chenfang Wang ◽

Jun Zhang ◽

Yu Bai ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Synaptic Plasticity ◽

Mouse Model ◽

Cognitive Behaviors ◽

Hippocampal Synaptic Plasticity ◽

Model Of Alzheimer’S Disease

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Corrigendum to “A tetra(ethylene glycol) derivative of benzothiazole aniline ameliorates dendritic spine density and cognitive function in a mouse model of Alzheimer's disease” [Exp. Neurol. 252 (2014) 105–113]

Experimental Neurology ◽

10.1016/j.expneurol.2014.07.017 ◽

2014 ◽

Vol 261 ◽

pp. 541-542

Author(s):

Jung Min Song ◽

Amanda Marie DiBattista ◽

You Me Sung ◽

Joo Myung Ahn ◽

R. Scott Turner ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Function ◽

Mouse Model ◽

Ethylene Glycol ◽

Dendritic Spine ◽

Spine Density ◽

Dendritic Spine Density ◽

Model Of Alzheimer’S Disease

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