NEURON-TARGETED CAVEOLIN-1 GENE THERAPY PRESERVES COGNITIVE FUNCTION AND SYNAPTIC PLASTICITY IN A MOUSE MODEL OF ALZHEIMER’S DISEASE (AD)

2019 ◽  
Vol 15 (7) ◽  
pp. P246-P248
Author(s):  
Shanshan Wang ◽  
Joseph Leem ◽  
Mckenzie Fannon ◽  
Natalia Kleschevnikova ◽  
Brian Head
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Gene Therapy ◽  
Synaptic Plasticity ◽  
Cognitive Function ◽  
Mouse Model ◽  
Caveolin 1 ◽  
Model Of Alzheimer’S Disease

scholarly journals Dysregulation of the mTOR Pathway Mediates Impairment of Synaptic Plasticity in a Mouse Model of Alzheimer's Disease

PLoS ONE ◽  
2010 ◽  
Vol 5 (9) ◽  
pp. e12845 ◽  
Author(s):  
Tao Ma ◽  
Charles A. Hoeffer ◽  
Estibaliz Capetillo-Zarate ◽  
Fangmin Yu ◽  
Helen Wong ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Synaptic Plasticity ◽  
Mouse Model ◽  
Mtor Pathway ◽  
Model Of Alzheimer’S Disease

scholarly journals Effect of transthyretin gene therapy in the 5XFAD mouse model of Alzheimer’s disease

2020 ◽  
Vol 16 (S9) ◽  
Author(s):  
Ana Rita Batista ◽  
Paola Rodriguez ◽  
Monique Otero ◽  
Robert M. King ◽  
Matthew J. Gounis ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Gene Therapy ◽  
Mouse Model ◽  
Model Of Alzheimer’S Disease ◽  
5Xfad Mouse

scholarly journals Disrupted-in-schizophrenia-1 protects synaptic plasticity in a transgenic mouse model of Alzheimer’s disease as a mitophagy receptor

Aging Cell ◽  
2018 ◽  
Vol 18 (1) ◽  
pp. e12860 ◽  
Author(s):  
Zhao-Tao Wang ◽  
Mei-Hong Lu ◽  
Yan Zhang ◽  
Wen-Li Ji ◽  
Lei Lei ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Synaptic Plasticity ◽  
Mouse Model ◽  
Transgenic Mouse ◽  
Transgenic Mouse Model ◽  
Model Of Alzheimer’S Disease
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