scholarly journals A novel feature selection method for microarray data classification based on hidden Markov model

2019 ◽  
Vol 95 ◽  
pp. 103213 ◽  
Author(s):  
Mohammadreza Momenzadeh ◽  
Mohammadreza Sehhati ◽  
Hossein Rabbani
Author(s):  
B. Venkatesh ◽  
J. Anuradha

In Microarray Data, it is complicated to achieve more classification accuracy due to the presence of high dimensions, irrelevant and noisy data. And also It had more gene expression data and fewer samples. To increase the classification accuracy and the processing speed of the model, an optimal number of features need to extract, this can be achieved by applying the feature selection method. In this paper, we propose a hybrid ensemble feature selection method. The proposed method has two phases, filter and wrapper phase in filter phase ensemble technique is used for aggregating the feature ranks of the Relief, minimum redundancy Maximum Relevance (mRMR), and Feature Correlation (FC) filter feature selection methods. This paper uses the Fuzzy Gaussian membership function ordering for aggregating the ranks. In wrapper phase, Improved Binary Particle Swarm Optimization (IBPSO) is used for selecting the optimal features, and the RBF Kernel-based Support Vector Machine (SVM) classifier is used as an evaluator. The performance of the proposed model are compared with state of art feature selection methods using five benchmark datasets. For evaluation various performance metrics such as Accuracy, Recall, Precision, and F1-Score are used. Furthermore, the experimental results show that the performance of the proposed method outperforms the other feature selection methods.


2009 ◽  
Vol 2009 ◽  
pp. 1-16 ◽  
Author(s):  
Nirmalya Bandyopadhyay ◽  
Tamer Kahveci ◽  
Steve Goodison ◽  
Y. Sun ◽  
Sanjay Ranka

Classification of cancers based on gene expressions produces better accuracy when compared to that of the clinical markers. Feature selection improves the accuracy of these classification algorithms by reducing the chance of overfitting that happens due to large number of features. We develop a new feature selection method called Biological Pathway-based Feature Selection (BPFS) for microarray data. Unlike most of the existing methods, our method integrates signaling and gene regulatory pathways with gene expression data to minimize the chance of overfitting of the method and to improve the test accuracy. Thus, BPFS selects a biologically meaningful feature set that is minimally redundant. Our experiments on published breast cancer datasets demonstrate that all of the top 20 genes found by our method are associated with cancer. Furthermore, the classification accuracy of our signature is up to 18% better than that of vant Veers 70 gene signature, and it is up to 8% better accuracy than the best published feature selection method, I-RELIEF.


2014 ◽  
Vol 11 (3) ◽  
pp. 243 ◽  
Author(s):  
Turker Tekin Erguzel ◽  
Serhat Ozekes ◽  
Selahattin Gultekin ◽  
Nevzat Tarhan

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