Attachment of Cartilage Wear Particles to the Synovium Negatively Impacts Friction Properties

2021 ◽  
pp. 110668
Author(s):  
Eben G. Estell ◽  
Lance A. Murphy ◽  
Lianna R. Gangi ◽  
Roshan P. Shah ◽  
Gerard A. Ateshian ◽  
...  
2008 ◽  
Vol 24 (3) ◽  
pp. 331-336
Author(s):  
T Meireles Sousa ◽  
A de Pádua Lima ◽  
B Hertsch

2010 ◽  
Vol 654-656 ◽  
pp. 2253-2256
Author(s):  
Christopher Allen ◽  
Zhong Xiao Peng ◽  
Ling Yin ◽  
Emma Carmichael

This work aimed to establish a suitable procedure for establishing wear particle hardness and to investigate if the hardness of articular cartilage wear particles increases with increasing grades of osteoarthritis. To achieve the goals a selection of fresh sheep knee joints were obtained and consequently worn in a specially designed wear simulator. Wear particles were then removed from the joint using a syringe and prepared for hardness testing. In order to test the hardness of the wear particle samples nanoindentation was used. Once completed statistical analyses and correlation analyses were performed in order to find any relationships present. This was the first time that the hardness of the wear particles was tested and studied. As a result of the tests performed a general relationship between wear particle hardness and osteoarthritis grade was able to be determined. It was also determined that further work needed to be conducted on the experimental procedure to increase the accuracy of the results obtained.


2011 ◽  
Vol 7 (2) ◽  
pp. 848-857 ◽  
Author(s):  
Keren Hakshur ◽  
Itai Benhar ◽  
Yaron Bar-Ziv ◽  
Nahum Halperin ◽  
David Segal ◽  
...  

2019 ◽  
Vol 37 (9) ◽  
pp. 1979-1987 ◽  
Author(s):  
Eben G. Estell ◽  
Amy M. Silverstein ◽  
Robert M. Stefani ◽  
Andy J. Lee ◽  
Lance A. Murphy ◽  
...  

2019 ◽  
Vol 7 (SI-TeMIC18) ◽  
Author(s):  
Norhanifah Abdul Rahman ◽  
Matzaini Katon Katon ◽  
Nurina Alya Zulkifli Zulkifli

Automatic Transmission (AT) system is efficient in the aspects of vehicle safety, comfort, reliability and driving performance. The objectives of this paper are to collect the oil samples from AT systems of engine bus according to manufacturer's recommendations and analyse collected oil samples using oil analysis technique. The sample transmission fluid which was taken from the AT gearbox has been experimentally analyzed. The oil samples were taken with an interval of 5,000km, 30,000km, 50,000km, 80,000km, 180,000km and 300,000km for AT bus operation. These samples then have been analyzed by comparing between new and used transmission fluid using Fourier Transform Infrared (FTIR) spectroscopy. Oil analysis by FTIR is a form of Predictive Maintenance (PdM) to avoid major failure in machine elements. Most machine elements are not easily accessible in the transmission system. Having a reliable technique would avoid the needs to open the components unnecessarily, hence, help to prevent catastrophic failure which are very costly, and ease of regular monitoring. In order to identify the major failures of automatic gearbox, forecasts can be made regarding the lube transmission fluid analysis test. By using this test, the minor problems can be determined before they become major failures. At the end of this research, the wear particles profile for interval mileage of AT system was obtained. Keywords: Wear, Automatic Transmission (AT), Transmission fluid, Fourier Transform Infrared (FTIR), Oil analysis.


2018 ◽  
Author(s):  
Reto Gieré ◽  
◽  
Frank Sommer ◽  
Volker Dietze ◽  
Anja Baum ◽  
...  
Keyword(s):  

2020 ◽  
Vol 27 (15) ◽  
pp. 18345-18354 ◽  
Author(s):  
Lydia J. Knight ◽  
Florence N. F. Parker-Jurd ◽  
Maya Al-Sid-Cheikh ◽  
Richard C. Thompson
Keyword(s):  

2021 ◽  
Vol 394 (10) ◽  
pp. 1991-2002
Author(s):  
Junchao Luo ◽  
Yin Zhang ◽  
Senbo Zhu ◽  
Yu Tong ◽  
Lichen Ji ◽  
...  

AbstractThe current understanding of osteoarthritis is developing from a mechanical disease caused by cartilage wear to a complex biological response involving inflammation, oxidative stress and other aspects. Nanoparticles are widely used in drug delivery due to its good stability in vivo and cell uptake efficiency. In addition to the above advantages, metal/metal oxide NPs, such as cerium oxide and manganese dioxide, can also simulate the activity of antioxidant enzymes and catalyze the degradation of superoxide anions and hydrogen peroxide. Degrading of metal/metal oxide nanoparticles releases metal ions, which may slow down the progression of osteoarthritis by inhibiting inflammation, promoting cartilage repair and inhibiting cartilage ossification. In present review, we focused on recent research works concerning osteoarthritis treating with metal/metal oxide nanoparticles, and introduced some potential nanoparticles that may have therapeutic effects.


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