scholarly journals Development of a patient-specific cerebral vasculature fluid-structure-interaction model

2022 ◽  
pp. 110896
Author(s):  
Kevin M. Moerman ◽  
Praneeta Konduri ◽  
Behrooz Fereidoonnezhad ◽  
Henk Marquering ◽  
Aad van der Lugt ◽  
...  
Trauma ◽  
2020 ◽  
pp. 146040862092172
Author(s):  
Reza Razaghi ◽  
Hasan Biglari ◽  
Alireza Karimi

Background There is a lack of knowledge on the magnitudes of the biomechanical stresses and deformations occurring in the cerebral arterial wall after traumatic brain injury (TBI). Experimental techniques are unable to calculate the stresses and deformations in the cerebral arterial wall after TBI; therefore, the application of numerical simulations, such as finite element modeling, is preferred. Methods This study was aimed to calculate the stresses and deformations as well as the alteration in the pressure and velocity of the blood in the cerebrovascular artery using a fluid–structure interaction model. Results The results revealed considerable increase in the pressure and velocity of the blood which might lead to cerebrovascular damage followed by hemorrhage. The arterial wall showed the highest deformation of 0.047 mm in the X direction which was higher than that in the Y (0.035–0.050 mm) and Z (0.019–0.030 mm) directions. Conclusions These results have implications not only for the understanding of the stresses and deformations in the cerebral artery because of TBI, but also for providing a comprehensive knowledge for biomechanical and medical experts in regard to thresholds of cerebrovascular damage for use in establishing preventive and/or treatment methods.


2021 ◽  
Author(s):  
Kevin Mattheus Moerman ◽  
Praneeta Konduri ◽  
Behrooz Fereidoonnezhad ◽  
Henk Marquering ◽  
Aad van der Lugt ◽  
...  

Development of in silico models of patient-specific cerebral artery networks presents several significant technical challenges: (i) The resolution and smoothness of medical CT images is much lower than the required element/cell length for FEA/CFD/FSI models; (ii) contact between vessels, and indeed self contact of high tortuosity vessel segments are not clearly identifiable from medical CT images. Commercial model construction software does not provide customised solutions for such technical challenges, with the result that accurate, efficient and automated development of patient-specific models of the cerebral vessels is not facilitated. This paper presents the development of a customised and automated platform for the generation of high resolution patient-specific FEA/CFD/FSI models from clinical images. This platform is used to perform the first fluid-structure-interaction patient-specific analysis of blood flow and artery deformation of an occluded cerebral vessel. Results demonstrate that in addition to flow disruption, clot occlusion significantly alters the geometry and strain distribution in the vessel network, with the blocked M2 segment undergoing axial elongation.The new computational approach presented in this study can be further developed as a clinical diagnostic tool and as a platform for thrombectomy device design.


Author(s):  
Mohammad Khairul Habib Pulok ◽  
Uttam K. Chakravarty

Abstract Rotary-wing aircrafts are the best-suited option in many cases for its vertical take-off and landing capacity, especially in any congested area, where a fixed-wing aircraft cannot perform. Rotor aerodynamic loading is the major reason behind helicopter vibration, therefore, determining the aerodynamic loadings are important. Coupling among aerodynamics and structural dynamics is involved in rotor blade design where the unsteady aerodynamic analysis is also imperative. In this study, a Bo 105 helicopter rotor blade is considered for computational aerodynamic analysis. A fluid-structure interaction model of the rotor blade with surrounding air is considered where the finite element model of the blade is coupled with the computational fluid dynamics model of the surrounding air. Aerodynamic coefficients, velocity profiles, and pressure profiles are analyzed from the fluid-structure interaction model. The resonance frequencies and mode shapes are also obtained by the computational method. A small-scale model of the rotor blade is manufactured, and experimental analysis of similar contemplation is conducted for the validation of the numerical results. Wind tunnel and vibration testing arrangements are used for the experimental validation of the aerodynamic and vibration characteristics by the small-scale rotor blade. The computational results show that the aerodynamic properties of the rotor blade vary with the change of angle of attack and natural frequency changes with mode number.


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