Learning From Failure at the CUTTING-EDGE of Transcatheter Mitral Valve Therapies

2021 ◽  
Vol 14 (18) ◽  
pp. 2022-2026
Author(s):  
Alessandro Sticchi ◽  
Fabien Praz ◽  
David Reineke ◽  
Stephan Windecker
2017 ◽  
Vol 25 (2) ◽  
pp. 40-42

Purpose This paper aims to review the latest management developments across the globe and pinpoints practical implications from cutting-edge research and case studies. Design/methodology/approach This briefing is prepared by an independent writer who adds their own impartial comments and places the articles in context. Findings Is it possible that change for good can lead to changes for the bad? In the context of any organization, there are any number of change programs that are being implemented at a given time. These will tend to be for product or service development, enabling efficiencies or supporting expansion strategies. Programs can also be about changing organizational culture, and such people-centric change programs can be some of the very hardest to embed. Originality/value The briefing saves busy executives and researchers hours of reading time by selecting only the very best, most pertinent information and presenting it in a condensed and easy-to-digest format.


Author(s):  
J. Temple Black

The output of the ultramicrotomy process with its high strain levels is dependent upon the input, ie., the nature of the material being machined. Apart from the geometrical constraints offered by the rake and clearance faces of the tool, each material is free to deform in whatever manner necessary to satisfy its material structure and interatomic constraints. Noncrystalline materials appear to survive the process undamaged when observed in the TEM. As has been demonstrated however microtomed plastics do in fact suffer damage to the top and bottom surfaces of the section regardless of the sharpness of the cutting edge or the tool material. The energy required to seperate the section from the block is not easily propogated through the section because the material is amorphous in nature and has no preferred crystalline planes upon which defects can move large distances to relieve the applied stress. Thus, the cutting stresses are supported elastically in the internal or bulk and plastically in the surfaces. The elastic strain can be recovered while the plastic strain is not reversible and will remain in the section after cutting is complete.


1999 ◽  
Vol 1 ◽  
pp. S87-S87
Author(s):  
R ROSENHEK ◽  
T BINDER ◽  
G PORENTA ◽  
G MAURER ◽  
H BAUMGARTNER

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