Outcomes of severe Legionella pneumonia requiring extracorporeal membrane oxygenation (ECMO)

2021 ◽  
Vol 61 ◽  
pp. 103-106
Author(s):  
Ali Naqvi ◽  
Sumit Kapoor ◽  
Mallika Pradhan ◽  
Peter V. Dicpinigaitis
2017 ◽  
Vol 34 (4) ◽  
pp. 344-350 ◽  
Author(s):  
Roberto Roncon-Albuquerque ◽  
Rodrigo Vilares-Morgado ◽  
Gert-Jan van der Heijden ◽  
João Ferreira-Coimbra ◽  
Paulo Mergulhão ◽  
...  

Objective: To analyze the management and outcome of patients with refractory respiratory failure complicating severe Legionella pneumonia rescued with extracorporeal membrane oxygenation (ECMO) in our Center. Design and Setting: Observational study of patients with refractory respiratory failure treated with ECMO in Hospital S.João (Porto, Portugal), between November 2009 and September 2016. Participants: A total of 112 patients rescued with ECMO, of which 14 had Legionella pneumonia. Results: Patients with Legionella pneumonia were slightly older than patients with acute respiratory failure of other etiologies (51 [48-56] vs 45 [35-54]), but with no significant differences in acute respiratory failure severity between groups: Pao2/Fio2 ratio 67 (60-75) versus 69 (55-85) and Respiratory Extracorporeal Membrane Oxygenation Survival Prediction score 4 (1-5) versus 2 (-1-4), respectively. Legionella pneumonia was associated with earlier ECMO initiation (days of invasive mechanical ventilation [IMV] before ECMO: 2.0 [1.0-4.0] vs 5.0 [2.0-9.5]). After IMV adjustment to “lung rest” settings, this group presented higher respiratory system (RS) static compliance (28.7 [18.8-37.4] vs 16.0 [10.0-20.8] mL/cmH2O) but required higher ECMO support (blood flow 5.0 [4.3-5.4] vs 4.2 [3.6-4.8]). Patients with Legionella pneumonia had shorter IMV (16 [14-23] vs 27 [20-42] days) and lower incidence of intensive care unit nosocomial infections (35.7% vs 64.3%), with a trend to higher hospital survival (85.7% vs 62.2%; P = .13). Conclusion: In Legionella pneumonia complicated by refractory respiratory failure, ECMO support allowed patient stabilization under lung protective ventilation and high survival rates. Timely ECMO referral should be considered for Legionella pneumonia failing conventional treatment.


1999 ◽  
Vol 28 (3) ◽  
pp. 686-687 ◽  
Author(s):  
Shingo Ichiba ◽  
David R. Jenkins ◽  
Giles J. Peek ◽  
Kevin J. Brennan ◽  
Hilliary M. Killer ◽  
...  

Perfusion ◽  
2009 ◽  
Vol 24 (1) ◽  
pp. 45-47 ◽  
Author(s):  
APS Thiara ◽  
V Høyland ◽  
H Norum ◽  
TA Aasmundstad ◽  
HM Karlsen ◽  
...  

We report the successful use of veno-venous extracorporeal membrane oxygenation (ECMO) in a 53-year-old patient with Legionella pneumonia and acute respiratory distress syndrome (ARDS) with severe barotraumas. The patient was supported for 59 days without any changes in the ECMO circuit. This is probably the longest support ever reported using the same oxygenator.


Author(s):  
A. A. Skopets ◽  
I. A. Kornilov ◽  
E. S. Afonin

Clinical observation of the patient with legionella pneumonia which developed in the setting of hairy-cell leukosis, required use of extracorporeal membrane oxygenation for controlling life-threatening hypoxia is presented. Active diagnostic approach for identification of the etiologic agent (Legionella pneumophila, Acinetobacter baumannii) that caused pneumonia, allowed to choose an optimum set of antibacterial agents and medicines for specific therapy of hemoblastosis (BRAFV600E mutation and use of Zelboraf). After correction of respiratory insufficiency and discontinue the patient from ECMO, we could reach hematologic remission and transfer the patient to the Institute of Hematology for further treatment.


2011 ◽  
Vol 59 (S 01) ◽  
Author(s):  
A Mühle ◽  
G Färber ◽  
T Doenst ◽  
M Barten ◽  
J Garbade ◽  
...  

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