Management of heart failure with concomitant complete atrioventricular block caused by a novel missense LMNA mutation

2021 ◽  
Vol 69 ◽  
pp. 27-29
Author(s):  
Mert İlker Hayıroğlu ◽  
Sena Sert Şekerci ◽  
Göksel Çinier ◽  
Şeyda Dereli ◽  
Ahmet İlker Tekkeşin
2009 ◽  
pp. S159-S166
Author(s):  
V Tomek ◽  
J Marek ◽  
H Jičínská ◽  
J Škovránek

Reliable diagnosis of congenital heart defects and arrhythmias in utero has been possible since the introduction of fetal echocardiography. The nation-wide prenatal ultrasound screening program in the Czech Republic enabled detection of cardiac abnormities in 1/3 of patients born with any congenital heart disease and up to 83 % of those with critical forms. Prenatal frequency of individual heart anomalies significantly differed from the postnatal frequency. Fetal isolated complete atrioventricular block and supraventricular tachycardia may lead to heart failure and are important causes of fetal mortality. The regression of heart failure was achieved by a conversion to the sinus rhythm in the supraventricular tachycardia and by increase of ventricular rate in the complete atrioventricular block.


Permanent pacemaker implantation and medical therapy due to complete atrioventricular block and comorbid cardiac pathology are considered at an example of clinical case. Permanent pacemaker solved the problem of AV-block, however, drug therapy due to arterial hypertension, heart failure and dyslipidemia is not canceled and requires modification. Permanent pacemaker solved the problem of AV-block, however, drug therapy due to arterial hypertension, heart failure and dyslipidemia is not canceled and requires modification.


2019 ◽  
Vol 6 (4) ◽  
pp. 686-693 ◽  
Author(s):  
Wei‐Chieh Lee ◽  
Hsiu‐Yu Fang ◽  
Huang‐Chung Chen ◽  
Yung‐Lung Chen ◽  
Tzu‐Hsien Tsai ◽  
...  

Angiology ◽  
2021 ◽  
pp. 000331972110287
Author(s):  
Turhan Turan ◽  
Faruk Kara ◽  
Selim Kul ◽  
Muhammet Rasit Sayın ◽  
Sinan Sahin ◽  
...  

The most common cause of complete atrioventricular block (CAVB) is age-related fibrotic degeneration and is referred to as primary idiopathic complete atrioventricular block (iCAVB). This study aims to investigate the relationship between iCAVB and arterial stiffness using the cardio-ankle vascular index (CAVI). In this study, of 205 CAVB patients, 41 patients with iCAVB implanted with a dual-chamber permanent pacemaker and 40 age- and gender-matched controls were studied. Arterial stiffness was assessed by a VaSera VS-1000 CAVI instrument. The CAVI values of patients with iCAVB were significantly higher compared with the controls (9.63 ± 1.42 vs 8.57 ± 1.12, P < .001). Idiopathic complete atrioventricular block frequency was higher among patients with abnormal CAVI values than those with borderline and normal CAVI ( P = .04). In multivariate analysis, only CAVI was an independent predictor of iCAVB after adjusting for other relevant factors (odds ratio, 2.575; 95% CI [1.390-4.770]; P = .003). The present study demonstrated that CAVI, as a marker of arterial stiffness, was increased among elderly patients with iCAVB. Thus, we provide a possible additional mechanism linking easily measured CAVI with iCAVB.


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