Manufacture of β-chitin nano- and microparticles from jumbo squid pen (Dosidicus gigas) and evaluation of their effect on mechanical properties and water vapour permeability of polyvinyl alcohol/chitosan films

Pendahuluan: Sistem penghantaran obat topikal melalui film forming system mampu mengatasi keterbatasan sediaan konvensional dengan membentuk film tipis in situ dan memberikan kontak lebih lama dikulit yang dapat mengontrol pelapasan obat. Polimer kitosan sebagai basis film forming system banyak digunakan karena sifatnya yang mukoadhesif dan mampu membentuk film tipis. Tujuan: Dalam review ini, dibahas penggunaan kitosan sebagai basis dalam sistem penghantaran obat yang telah banyak diaplikasikan dengan berbagai aktivitas biologis. Hasil: Dalam formula FFS, perlu diperhatikan parameter kritis yang mempengaruhi formulasi film forming system seperti pemilihan konsentrasi polimer, kombinasi dengan polimer lain seperti polimer sintetik polyvinyl alcohol (PVA), derajat deasetilasi kitosan yang rendah untuk meningkatkan sifat mekanik dan pembentukan film yang lebih baik, penambahan eksipien seperti plasticizer, humektan dan crosslinker yang dilaporkan berpengaruh terhadap sifat fisika kimia obat. Parameter fisikokimia yang diinginkan harus memiliki sifat mekanik yang mampu mengatasi tekanan takensial gerakan tubuh, pH untuk formula topikal berada pada rentang 4 – 6, waktu pembentukan film kurang dari 15 menit serta water vapour permeability (WVP) lebih dari 0,05 g/cm2. 24 jam. Kesimpulan: Dari berbagai hasil penelitian, dilaporkan bahwa film forming system menggunakan basis kitosan menjadi salah satu pendekatan yang potensial dalam sistem penghantaran obat untuk meningkatkan efektivitas permeasi dan penetrasi yang lebih baik.

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Structuration of ionic liquids in a poly(butylene-adipate-co-terephthalate) matrix: its influence on the water vapour permeability and mechanical properties

Green Chemistry ◽

10.1039/c4gc00969j ◽

2014 ◽

Vol 16 (8) ◽

pp. 3758-3762 ◽

Cited By ~ 21

Author(s):

Sébastien Livi ◽

Valeria Bugatti ◽

Bluma Guenther Soares ◽

Jannick Duchet-Rumeau

Keyword(s):

Mechanical Properties ◽

Ionic Liquids ◽

Water Vapour ◽

Building Blocks ◽

Water Vapour Permeability ◽

Vapour Permeability

The use of new building blocks based on ionic liquids to develop materials combining a structuration on the nanoscale with the dramatic water vapour permeability and mechanical properties was investigated.

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Hydrostatic Resistance and Mechanical Behaviours of Breathable Layered Waterproof Fabrics

Fibres and Textiles in Eastern Europe ◽

10.5604/01.3001.0010.7805 ◽

2018 ◽

Vol 26 (1(127)) ◽

pp. 108-112 ◽

Cited By ~ 1

Author(s):

Iwona Frydrych ◽

Pavla Tesinova ◽

Lubos Hes ◽

Veerakumar Arumugam

Keyword(s):

Mechanical Properties ◽

Water Vapour ◽

Water Vapour Permeability ◽

Cold Weather ◽

Test Results ◽

Vapour Permeability ◽

Different Types ◽

Mechanical Behaviours ◽

Pass Through ◽

Hydrophilic Membrane

Breathable layered waterproof fabrics have good applications in the fields of sportswear, protective clothing and construction industries. The properties of these fabrics in allowing water vapour to pass through while preventing liquid water from entering have made them unique. The mechanical properties of these fabrics are also very important for the satisfaction of the wearers. The layered constructions of these fabrics with different characteristic properties contribute to the influence on their hydrostatic resistance, mechanical properties and water vapour permeability. This study presents an experiment on eight different types of hydrophobic and hydrophilic membrane laminated layered fabrics used as sportswear during hot or cold weather. The hydrostatic resistance, tensile strength, stiffness and water vapour permeability of these fabrics were evaluated by varying different fabric parameters in the experiment. It was found from the test results that the fabric density, thickness and weight as well as types of membranes and layers have a significant effect on those properties of the layered fabrics.

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