The book "Outlining Clinical Research" by Stephen B. Hulley, Steven R. Cummings, Warren S. Browner, Deborah G. Grady and Thomas B. Newman, translated by Michael Schimdt Duncan and André Garcia Islabão, and published, in 2015, by the publisher Artmed. As a primary focus, it is the instrumentalization of readers so that they can formulate research questions and plan an effective, systemic and ethical study design.