In Vivo Survival of Mesenchymal Stromal Cell–Enhanced Decellularized Nerve Grafts for Segmental Peripheral Nerve Reconstruction

2019 ◽  
Vol 44 (6) ◽  
pp. 514.e1-514.e11 ◽  
Author(s):  
Nadia Rbia ◽  
Liselotte F. Bulstra ◽  
Roman Thaler ◽  
Steven E.R. Hovius ◽  
Andre J. van Wijnen ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Mesenchymal Stromal Cell ◽  
Stromal Cell ◽  
Nerve Reconstruction ◽  
Nerve Grafts

scholarly journals Enriched osteogenic potential of CD317-negative mesenchymal stromal cell populations in vitro and in vivo

Bone Reports ◽  
2020 ◽  
Vol 13 ◽  
pp. 100509
Author(s):  
Alasdair G. Kay ◽  
James Fox ◽  
Andrew Stone ◽  
Sally James ◽  
Elizabeth Kapasa ◽  
...  
Keyword(s):  
Mesenchymal Stromal Cell ◽  
Stromal Cell ◽  
Osteogenic Potential ◽  
Cell Populations

Immortalized human fetal bone marrow-derived mesenchymal stromal cell expressing suicide gene for anti-tumor therapy in vitro and in vivo

Cytotherapy ◽  
2013 ◽  
Vol 15 (12) ◽  
pp. 1484-1497 ◽  
Author(s):  
Wayne Y.W. Lee ◽  
Ting Zhang ◽  
Carol P.Y. Lau ◽  
C.C. Wang ◽  
Kai-Ming Chan ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Mesenchymal Stromal Cell ◽  
Stromal Cell ◽  
Tumor Therapy ◽  
Suicide Gene ◽  
Fetal Bone

scholarly journals Detergent-free Decellularized Nerve Grafts for Long-gap Peripheral Nerve Reconstruction

2014 ◽  
Vol 2 (8) ◽  
pp. e201 ◽  
Author(s):  
Srikanth Vasudevan ◽  
Jiying Huang ◽  
Barry Botterman ◽  
Hani S. Matloub ◽  
Edward Keefer ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Nerve Reconstruction ◽  
Nerve Grafts ◽  
Long Gap

scholarly journals Epicardial Placement of Mesenchymal Stromal Cell-sheets for the Treatment of Ischemic Cardiomyopathy; In Vivo Proof-of-concept Study

2014 ◽  
Vol 22 (10) ◽  
pp. 1864-1871 ◽  
Author(s):  
Nobuko Tano ◽  
Takuya Narita ◽  
Masahiro Kaneko ◽  
Chiho Ikebe ◽  
Steven R Coppen ◽  
...  
Keyword(s):  
Mesenchymal Stromal Cell ◽  
Ischemic Cardiomyopathy ◽  
Stromal Cell ◽  
Proof Of Concept ◽  
Cell Sheets ◽  
Concept Study

scholarly journals Effects of Canine and Murine Mesenchymal Stromal Cell Transplantation on Peripheral Nerve Regeneration

2017 ◽  
Vol 10 (1) ◽  
pp. 83-92 ◽  
Author(s):  
Diego Noe Rodriguez Sanchez ◽  
Matheus Bertanha ◽  
Thiago Dias Fernandes ◽  
Luiz Antônio de Lima Resende ◽  
Elenice Deffune ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Cell Transplantation ◽  
Mesenchymal Stromal Cell ◽  
Stromal Cell ◽  
Peripheral Nerve Regeneration

In Vitro and In Vivo Magnetic Resonance Tracking of Sinerem-Labeled Human Umbilical Mesenchymal Stromal Cell-Derived Schwann Cells

2010 ◽  
Vol 31 (3) ◽  
pp. 365-375 ◽  
Author(s):  
Qiang Xu ◽  
Hong-Tian Zhang ◽  
Ke Liu ◽  
Jun-Hua Rao ◽  
Xiao-Ming Liu ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Schwann Cells ◽  
Mesenchymal Stromal Cell ◽  
Stromal Cell

scholarly journals Sustained Released of Bioactive Mesenchymal Stromal Cell-Derived Extracellular Vesicles from 3D-Printed Gelatin Methacrylate Hydrogels

2021 ◽  
Author(s):  
Louis J Born ◽  
Shannon T McLoughlin ◽  
Dipankar Dutta ◽  
Bhushan Mahadik ◽  
Xiaofeng Jia ◽  
...  
Keyword(s):  
Extracellular Vesicles ◽  
Stromal Cells ◽  
Mesenchymal Stromal Cell ◽  
Stromal Cell ◽  
Therapeutic Potential ◽  
Burst Release ◽  
Gap Closure ◽  
3D Printed ◽  
Rapid Clearance

Extracellular vesicles (EVs) represent an emerging class of therapeutics with significant potential and broad applicability. However, a general limitation is their rapid clearance after administration. Thus, methods to enable sustained EV release are of great potential value. Here, we demonstrate that EVs from mesenchymal stem/stromal cells (MSCs) can be incorporated into 3D-printed gelatin methacrylate (GelMA) hydrogel bioink, and that the initial burst release of EVs can be reduced by increasing the concentration of crosslinker during gelation. Further, the data show that MSC EV bioactivity in an endothelial gap closure assay is retained after the 3D printing and photocrosslinking processes. Our group previously showed that MSC EV bioactivity in this assay correlates with pro-angiogenic bioactivity in vivo, thus these results indicate therapeutic potential of MSC EV-laden GelMA bioinks.

Peripheral nerve reconstruction using acellular nerve grafts

2000 ◽  
Vol 191 (4) ◽  
pp. S80-S81
Author(s):  
Steven C. Haase ◽  
Paul S. Cederna ◽  
Robert G. Dennis ◽  
William M. Kuzon
Keyword(s):  
Peripheral Nerve ◽  
Nerve Reconstruction ◽  
Nerve Grafts
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