Use of polymerase chain reaction in the diagnosis of Whipple's disease

2015 ◽  
Vol 21 (12) ◽  
pp. 885-888 ◽  
Author(s):  
Masanori Kono ◽  
Kei Yamamoto ◽  
Maki Nagamatsu ◽  
Satoshi Kutsuna
Keyword(s):  
Polymerase Chain Reaction ◽  
Whipple’S Disease ◽  
Chain Reaction ◽  
Whipple's Disease ◽  
Polymerase Chain

Polymerase chain reaction?based detection ofTropheryma whippelii in central nervous system Whipple's disease

1997 ◽  
Vol 42 (1) ◽  
pp. 120-124 ◽  
Author(s):  
T. Lynch ◽  
J. Odel ◽  
D. N. Fredericks ◽  
E. D. Louis ◽  
S. Forman ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Polymerase Chain Reaction ◽  
Nervous System ◽  
Whipple’S Disease ◽  
Chain Reaction ◽  
Whipple's Disease ◽  
Polymerase Chain

Can Whipple's Disease Be Transmitted by Gastroscopes?

2003 ◽  
Vol 24 (3) ◽  
pp. 191-194 ◽  
Author(s):  
Bernard La Scola ◽  
Jean-Marc Rolain ◽  
Max Maurin ◽  
Didier Raoult
Keyword(s):  
Polymerase Chain Reaction ◽  
Bactericidal Activity ◽  
False Positive ◽  
Tropheryma Whipplei ◽  
Whipple’S Disease ◽  
Chain Reaction ◽  
Whipple's Disease ◽  
Cell Monolayers ◽  
Polymerase Chain ◽  
Positive Results

AbstractObjective:To determine whether disinfection protocols currently used for gastroscopes are effective against cultures ofTropheryma whipplei.Design:The bactericidal activity of 2% glutaraldehyde and two peracetic acids on the Twist-Marseille strain ofT. whippleigrown in cell monolayers was determined.Patients:Two patients who were diagnosed as having Whipple's disease 3 years after they had had intestinal biopsies.Results:The disinfectants reduced bacteria by approximately 2 log10to 3 log10after 5 to 60 minutes of contact.Conclusion:The bactericidal activity of a disinfectant is usually considered significant if it causes a 5 log10or greater reduction in viable bacterial titers. Disinfecting gastroscopes with2%glutaraldehyde or peracetic acids for 20 minutes may be insufficient to prevent transmission ofT. whippleion the instruments or stop false-positive results on polymerase chain reaction.

scholarly journals Whipple's disease: comparison of histology with diagnosis based on polymerase chain reaction in four consecutive cases.

Gut ◽  
1997 ◽  
Vol 40 (3) ◽  
pp. 425-427 ◽  
Author(s):  
C Muller ◽  
D Petermann ◽  
C Stain ◽  
H Riemer ◽  
H Vogelsang ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Whipple’S Disease ◽  
Chain Reaction ◽  
Whipple's Disease ◽  
Polymerase Chain

scholarly journals Potential Role for Urine Polymerase Chain Reaction in the Diagnosis of Whipple’s Disease

2018 ◽  
Vol 68 (7) ◽  
pp. 1089-1097 ◽  
Author(s):  
Annette Moter ◽  
Matthias Janneck ◽  
Manuel Wolters ◽  
Christof Iking-Konert ◽  
Alexandra Wiessner ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Potential Role ◽  
Whipple’S Disease ◽  
Chain Reaction ◽  
Whipple's Disease ◽  
Polymerase Chain

Polymerase chain reaction of cerebrospinal fluid to diagnose Whipple's disease

The Lancet ◽  
1996 ◽  
Vol 347 (8997) ◽  
pp. 329 ◽  
Author(s):  
L. Cohen ◽  
K. Berthet ◽  
C. Dauga ◽  
L. Thivart ◽  
C. Pierrot-Deseilligny
Keyword(s):  
Polymerase Chain Reaction ◽  
Cerebrospinal Fluid ◽  
Whipple’S Disease ◽  
Chain Reaction ◽  
Whipple's Disease ◽  
Polymerase Chain

scholarly journals Whipple's Disease: the First Japanese Case Diagnosed by Electron Microscopy and Polymerase Chain Reaction

2004 ◽  
Vol 43 (7) ◽  
pp. 566-570 ◽  
Author(s):  
Tatsuji YOGI ◽  
Akira HOKAMA ◽  
Fukunori KINJO ◽  
Ryosaku TOMIYAMA ◽  
Michio KOIDE ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Polymerase Chain Reaction ◽  
Whipple’S Disease ◽  
Chain Reaction ◽  
Whipple's Disease ◽  
Japanese Case ◽  
Polymerase Chain
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