Fabrication of pH responsive coacervates using a polycation-b-polypropylene glycol diblock copolymer for versatile delivery platforms

2020 ◽  
Vol 90 ◽  
pp. 36-46
Author(s):  
Mani Gajendiran ◽  
Sungjun Kim ◽  
Heejung Jo ◽  
Kyobum Kim
Keyword(s):  
Diblock Copolymer ◽  
Polypropylene Glycol ◽  
Ph Responsive

pH-responsive micelles and vesicles formed from a water-soluble schizophrenic diblock copolymer

2014 ◽  
Vol 45 (6) ◽  
pp. 3117-3123 ◽  
Author(s):  
Ryusuke Enomoto ◽  
Mehul Khimani ◽  
Pratap Bahadur ◽  
Shin-ichi Yusa
Keyword(s):  
Diblock Copolymer ◽  
Water Soluble ◽  
Ph Responsive

Amphiphilic Asymmetric Diblock Copolymer with pH-Responsive Fluorescent Properties

2021 ◽  
pp. 1346-1352
Author(s):  
Yanyao Zhang ◽  
Yusheng Tang ◽  
Junliang Zhang ◽  
Simon Harrisson
Keyword(s):  
Diblock Copolymer ◽  
Ph Responsive ◽  
Fluorescent Properties

Effects of copolymer concentration and chain length on the pH-responsive behavior of diblock copolymer micellar films

2006 ◽  
Vol 303 (2) ◽  
pp. 372-379 ◽  
Author(s):  
Kenichi Sakai ◽  
Emelyn G. Smith ◽  
Grant B. Webber ◽  
Erica J. Wanless ◽  
Vural Bütün ◽  
...  
Keyword(s):  
Chain Length ◽  
Diblock Copolymer ◽  
Ph Responsive ◽  
Copolymer Concentration ◽  
Responsive Behavior

scholarly journals pH-Responsive Pickering emulsion stabilized by polymer-coated silica nanoaggregates and applied to recyclable interfacial catalysis

RSC Advances ◽  
2020 ◽  
Vol 10 (69) ◽  
pp. 42423-42431
Author(s):  
Ruidong Luo ◽  
Jinfeng Dong ◽  
Yunbai Luo
Keyword(s):  
Diblock Copolymer ◽  
Trifluoroacetic Acid ◽  
Fumed Silica ◽  
Pickering Emulsion ◽  
Emulsion System ◽  
Ph Responsive ◽  
Interfacial Catalysis

We synthesized a diblock copolymer and grafted it onto fumed silica in the presence of trifluoroacetic acid to obtain a pH-responsive Pickering emulsion system stabilized by polymer-coated nanoaggregates, P-Si.

pH-Responsive Vesicles from a Schizophrenic Diblock Copolymer

2010 ◽  
Vol 211 (14) ◽  
pp. 1530-1537 ◽  
Author(s):  
Jianzhong Du ◽  
Rachel K. O'Reilly
Keyword(s):  
Diblock Copolymer ◽  
Ph Responsive

pH-responsive microspheres encapsulated with iron oxide nanoaggregates for gastrointestinal delivery

2012 ◽  
Vol 27 (1) ◽  
pp. 54-66 ◽  
Author(s):  
Young Ju Son ◽  
Hyuk Sang Yoo
Keyword(s):  
Iron Oxide ◽  
Block Copolymer ◽  
Block Copolymers ◽  
Diblock Copolymer ◽  
Ph Responsive ◽  
Polymeric Microspheres ◽  
Intestinal Delivery ◽  
Poly Ethylene ◽  
The Stability

Block copolymer-stabilized iron oxide nanoaggregates were fabricated into pH-responsive polymeric microspheres for intestinal delivery of the magnetic nanoaggregates. A diblock copolymer consisted of methoxy poly(ethylene glycol) (mPEG) and poly(e-caprolactone) (PCL) was synthesized by ring-opening polymerization. Microspheres, consisted of Eudragit L100-55 encapsulate and stabilized magnetic nanoaggregates, were prepared by an oil-in-oil emulsification technique. The magnetization of the microspheres decreased, and the stability of the magnetic nanoaggregates in aqueous solutions increased as the amount of block copolymers in the microspheres increased. The encapsulated magnetic nanoaggregates were visualized by scanning electron microscopy and energy-dispersive X-ray spectroscopy. The encapsulation efficiency of nanoaggregates of the microspheres increased as the amount of diblock copolymer in the nanoaggregates was increased. The in vitro experiments confirmed the pH-dependent release of the nanoaggregates from the microspheres. The microspheres were administered to the animals by oral gavages, and the nanoaggregates in small intestines were visualized by histological examination of intestinal inner walls. Higher amounts of the block copolymer in the nanoaggregates increased the uptake efficiency in the intestinal tissues. Thus, the incorporation of the block copolymers in the magnetic nanoaggregates increased the intestinal absorption of the aggregates and Eudragit microspheres and effectively protected the nanoaggregates at low pH conditions of the stomach area.

scholarly journals Agarose Hydrogels Embedded with pH-Responsive Diblock Copolymer Micelles for Triggered Release of Substances

2013 ◽  
Vol 14 (8) ◽  
pp. 2713-2723 ◽  
Author(s):  
Naixiong Jin ◽  
Emily A. Morin ◽  
Daniel M. Henn ◽  
Yu Cao ◽  
Jeremiah W. Woodcock ◽  
...  
Keyword(s):  
Diblock Copolymer ◽  
Ph Responsive ◽  
Triggered Release ◽  
Copolymer Micelles
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