Redox/pH-dual responsive functional hollow silica nanoparticles for hyaluronic acid-guided drug delivery

2021 ◽  
Author(s):  
Donghun Shin ◽  
Seungki Lee ◽  
Hyun Sung Jang ◽  
Ji Bong Joo ◽  
Inhee Choi
Keyword(s):  
Drug Delivery ◽  
Hyaluronic Acid ◽  
Silica Nanoparticles ◽  
Hollow Silica ◽  
Dual Responsive ◽  
Hollow Silica Nanoparticles

scholarly journals Hybrid Materials based on Silica Nanostructures for Biomedical Scaffolds (Bone Regeneration) and Drug Delivery

2021 ◽  
pp. 103-120
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Bone Regeneration ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Living Cells ◽  
Hollow Silica ◽  
Low Toxicity ◽  
Silica Nanostructures ◽  
Hollow Silica Nanoparticles

Silica nanoparticles with nanoporous nature are introduced as thermally and chemically stable nanomaterials with controllable porosity and morphology. The nanoparticles can be divided into three groups: microporous, mesoporous, and macroporous based on the porous size. The use of these materials for different applications is associated with their unique properties as disinfectants. This chapter discusses different synthesis methodologies to prepare well-dispersed mesoporous silica nanoparticles (MSNs) and hollow silica nanoparticles (HSNs) with tunable dimensions ranging from a few to hundreds of nanometers of different mesostructures. Several good characteristics of the MSNs, best biocompatibility and low toxicity, are proposed as the basis of the carrier for the controlled release of drugs, genes into living cells and bone regeneration.

Fabrication of Single-Hole Glutathione-Responsive Degradable Hollow Silica Nanoparticles for Drug Delivery

2014 ◽  
Vol 6 (15) ◽  
pp. 12600-12608 ◽  
Author(s):  
Dongdong Wang ◽  
Zhigang Xu ◽  
Zhenjie Chen ◽  
Xiaoyan Liu ◽  
Cuilan Hou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Silica Nanoparticles ◽  
Hollow Silica ◽  
Single Hole ◽  
Hollow Silica Nanoparticles

A pH-responsive nanocontainer based on hydrazone-bearing hollow silica nanoparticles for targeted tumor therapy

2016 ◽  
Vol 4 (26) ◽  
pp. 4594-4604 ◽  
Author(s):  
Liangliang Dai ◽  
Qingfeng Zhang ◽  
Xinkun Shen ◽  
Qiang Sun ◽  
Caiyun Mu ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Silica Nanoparticles ◽  
High Efficiency ◽  
Tumor Therapy ◽  
Ph Responsive ◽  
Hollow Silica ◽  
Good Biocompatibility ◽  
Hollow Silica Nanoparticles

pH-responsive hollow silica nanoparticles blocked with hyaluronic acid molecules for targeted tumor therapy with high efficiency and good biocompatibility.

Hollow Silica Nanoparticles Penetrate the Peripheral Nerve and Enhance the Nerve Blockade from Tetrodotoxin

Nano Letters ◽  
2017 ◽  
Vol 18 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Qian Liu ◽  
Claudia M. Santamaria ◽  
Tuo Wei ◽  
Chao Zhao ◽  
Tianjiao Ji ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Silica Nanoparticles ◽  
Hollow Silica ◽  
Nerve Blockade ◽  
Hollow Silica Nanoparticles
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