Endobronchial ultrasound-guided biopsy in the evaluation of intrathoracic lymphadenopathy in suspected tuberculosis: A minimally invasive technique with a high diagnostic yield

2009 ◽  
Vol 58 (4) ◽  
pp. 309-311 ◽  
Author(s):  
Daniel P. Steinfort ◽  
Douglas F. Johnson ◽  
Tom G. Connell ◽  
Louis B. Irving
Keyword(s):  
Minimally Invasive ◽  
Diagnostic Yield ◽  
Minimally Invasive Technique ◽  
Endobronchial Ultrasound ◽  
Invasive Technique ◽  
Ultrasound Guided ◽  
High Diagnostic Yield ◽  
Guided Biopsy ◽  
Suspected Tuberculosis ◽  
Ultrasound Guided Biopsy

Hemomediastinum From Endobronchial Ultrasound-Guided Biopsy Leading to Diagnosis of Acquired Hemophilia

CHEST Journal ◽  
2016 ◽  
Vol 150 (4) ◽  
pp. 1040A
Author(s):  
Tasnim Lat ◽  
Kirill Lipatov ◽  
Thomas Delmas ◽  
Shekhar Ghamande ◽  
Robert Long
Keyword(s):  
Endobronchial Ultrasound ◽  
Ultrasound Guided ◽  
Acquired Hemophilia ◽  
Guided Biopsy ◽  
Ultrasound Guided Biopsy

scholarly journals Safety and diagnostic yield of endobronchial ultrasound-guided lymph node biopsy in children and adolescents with suspected tuberculosis

2021 ◽  
Author(s):  
Michael Barker ◽  
Annette Günther ◽  
Henrik Wurps ◽  
Andreas Gebhardt ◽  
Nicolas Schönfeld ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Diagnostic Yield ◽  
Sampling Site ◽  
Case Series ◽  
Positive Culture ◽  
Endobronchial Ultrasound ◽  
Gastric Aspirate ◽  
Ultrasound Guided ◽  
Transbronchial Needle Aspiration ◽  
Suspected Tuberculosis

Referring to a literature review published recently in this Journal, we report a single-center case series of 45 children and adolescents (age 2-17 years) with suspected tuberculosis (TB) and negative microscopy on repeated sputum or gastric aspirate samples. All subjects underwent flexible airway endoscopy including bronchoalveolar lavage (BAL) and endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) without adverse events. Among 41 subjects with a final TB diagnosis, Mycobacterium tuberculosis was detected by PCR and/or culture in 20 (49% bacteriological confirmation) with 11 cases relying exclusively on results from TBNA samples. Only 7 of 17 positive culture results related to sputum (17% confirmation rate), and 9 of 17 on the combination of sputum and BAL (22%) respectively. The sampling site of a person’s first positive culture was TBNA in 13 of 17 cases (76%). Bacteriological confirmation was essential for diagnostic accuracy and tailored treatment based on individual drug susceptibility testing. We therefore recommend the inclusion of bronchoscopy and EBUS-TBNA in a comprehensive diagnostic protocol for smear-negative pediatric TB suspects.

The Techniques of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration

2011 ◽  
Vol 6 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Takahiro Nakajima ◽  
Kazuhiro Yasufuku
Keyword(s):  
Lymph Node ◽  
Diagnostic Yield ◽  
Mediastinal Lymph Node ◽  
Needle Aspiration ◽  
Endobronchial Ultrasound ◽  
Lymph Node Staging ◽  
Ultrasound Guided ◽  
Surgical Biopsy ◽  
Transbronchial Needle Aspiration ◽  
High Diagnostic Yield

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive modality for mediastinal lymph node staging in lung cancer patients as well as for the diagnosis of mediastinal and hilar adenopathy. The high diagnostic yield of EBUS-TBNA for lymph node staging has been shown in systematic reviews and meta-analysis. It has attracted physicians and surgeons as an alternative modality to surgical biopsy for the assessment of patients with enlarged mediastinal and/or hilar lymph nodes. Cell blocks obtained by EBUS-TBNA can be applicable not only for pathologic diagnosis but also for further investigations such as immunohistochemistry and fluorescence in situ hybridization. In addition, samples obtained by EBUS-TBNA can also be used for molecular analysis. Unlike regular bronchoscopy, EBUS-TBNA uses the convex probe EBUS with an ultrasound probe on the tip of a flexible bronchoscope. It is important for the bronchoscopist to fully understand the mediastinal anatomy and be able to correlate it with the ultrasound images for a successful EBUS-TBNA. The dedicated transbronchial needle used for EBUS-TBNA is somewhat different from an ordinary transbronchial biopsy forceps. Training is mandatory for achieving high diagnostic yield without complications. The learning curve of EBUS-TBNA is different from each physician, and continuous training program will be needed for impartiality. This article explains the detailed techniques of EBUS-TBNA to master this innovative procedure.

Metastatic Extraspinal Ependymoma Masquerading as Carcinoid Tumor: Diagnosis Based on Endobronchial Ultrasound Guided Biopsy

CHEST Journal ◽  
2011 ◽  
Vol 140 (4) ◽  
pp. 13A
Author(s):  
Joshua Farkas ◽  
Llewellyn Foulke ◽  
Anwar Haque ◽  
Marc Judson ◽  
Mark Napier
Keyword(s):  
Carcinoid Tumor ◽  
Tumor Diagnosis ◽  
Endobronchial Ultrasound ◽  
Ultrasound Guided ◽  
Guided Biopsy ◽  
Extraspinal Ependymoma ◽  
Ultrasound Guided Biopsy

scholarly journals Can Computed Tomography Characteristics Predict Outcomes in Patients Undergoing Radial Endobronchial Ultrasound-Guided Biopsy of Peripheral Lung Lesions?

2014 ◽  
Vol 9 (9) ◽  
pp. 1393-1397 ◽  
Author(s):  
Matthew Evison ◽  
Philip A.J. Crosbie ◽  
Julie Morris ◽  
Julie Martin ◽  
Philip V. Barber ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Endobronchial Ultrasound ◽  
Ultrasound Guided ◽  
Lung Lesions ◽  
Guided Biopsy ◽  
Peripheral Lung ◽  
Ultrasound Guided Biopsy
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