Complexes of ferriheme nitrophorin 4 with low-molecular weight thiol(ate)s occurring in blood plasma

2013 ◽  
Vol 122 ◽  
pp. 38-48 ◽  
Author(s):  
Chunmao He ◽  
Koji Nishikawa ◽  
Özlen F. Erdem ◽  
Edward Reijerse ◽  
Hideaki Ogata ◽  
...  
2013 ◽  
Vol 59 (3) ◽  
pp. 358-373 ◽  
Author(s):  
I.N. Vasilyeva ◽  
V.N. Zinkin

The low-molecular-weight DNA appears in blood plasma of irradiated rats, and its content correlates directly with the irradiation dose. Cloning has shown, that enrichment of low-molecular-weight DNA with G+C content and features of its nucleotide sequences point to its ability to form rather stable nucleosomes. DNA obtained after irradiation of rats with principally different doses 8 and 100 Gy differed not only quantitatively, but also by content of the dinucleotides CpG and CpT; this suggests their origin from different sites of genome. For the first time it has been shown that exposure to low-frequency noise results in an increase of the contents of blood plasma low-molecular-weight DNA. In stroke patients blood concentrations of this DNA increased 3 days after the beginning of the acute period, and dynamics of its excretion differs in ischemic and hemorrhagic forms; in the case of ischemia low-molecular-weight DNA appears in cerebrospinal fluid. The chronic obstructive pulmonary disease in the state of remission is characterized by the decline of the level of low-molecular-weight DNA in the blood plasma unlike in the case of the chronic nonobstructive bronchitis. The clear dependence between formation and special features of the low-molecular-weight DNA fraction in blood plasma makes it possible to consider the low-molecular fraction as an universal index of apoptosis, which allows to distinguish basically different conditions of the body.


2018 ◽  
Vol 72 (4) ◽  
pp. 195-203 ◽  
Author(s):  
Alexander Vladimirovich Ivanov ◽  
Valery Vasilʼevich Alexandrin ◽  
Alexander Alexandrovich Paltsyn ◽  
Edward Danielevich Virus ◽  
Ksenya Alexandrovna Nikiforova ◽  
...  

2006 ◽  
Vol 61 (11) ◽  
pp. 1093-1099 ◽  
Author(s):  
I. O. Melnikov ◽  
I. V. Nazimov ◽  
E. A. Stukacheva ◽  
Yu. M. Glubokov

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