scholarly journals Acanthamoeba keratitis in noncompliant soft contact lenses users: Genotyping and risk factors, a study from Cairo, Egypt

2018 ◽  
Vol 11 (3) ◽  
pp. 377-383 ◽  
Author(s):  
Eman E. Taher ◽  
Eman M.H. Méabed ◽  
Islam Abdallah ◽  
Wafaa Y. Abdel Wahed
2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Ching-Hsi Hsiao ◽  
Lung-Kun Yeh ◽  
Hung-Chi Chen ◽  
Hsin-Chiung Lin ◽  
Phil Y. F. Chen ◽  
...  

Purpose.Alternariaspp. are an uncommon cause of mycotic keratitis. Previous studies onAlternariakeratitis have generally been limited to case reports. We examined the clinical characteristics ofAlternariakeratitis in this study.Methods.The characteristics and outcomes of 7 patients with culture-provenAlternariakeratitis treated in our hospital were compared with 25 previously reported cases.Results.The risk factors forAlternariakeratitis were trauma in 5 patients and soft contact lenses in 1 patient. Six patients with early diagnosis (<2 weeks) were cured with medical antimicrobial treatment; a patch graft was required in 1 patient with perforation. When incorporated with previous reports onAlternariakeratitis(n=32), 14 (44%) infections followed trauma, 10 (31%) were associated with preexisting corneal disease or previous ocular surgery, and 5 (16%) occurred in soft contact lens wearers. Successful medical treatment was achieved in 23 (72%) patients, including 10 out of 21 eyes (48%) treated with natamycin and/or amphotericin B. Therapeutic penetrating keratoplasty was performed in 9 (28%) cases.Conclusions.Alternariakeratitis is generally associated with specific risk factors and responds to medical treatment when early diagnosis is performed and prompt antifungal treatment is initiated.


2005 ◽  
Vol 5 (6) ◽  
pp. 392 ◽  
Author(s):  
Yuichi Kaji ◽  
Beihua Hu ◽  
Keisuke Kawana ◽  
Tetsuro Oshika

2017 ◽  
Vol 58 (2) ◽  
pp. 1218 ◽  
Author(s):  
Ángel Ortillés ◽  
Pilar Goñi ◽  
Encarnación Rubio ◽  
Marta Sierra ◽  
Ekaterina Gámez ◽  
...  

2021 ◽  
Vol 20 (4) ◽  
pp. 177-181
Author(s):  
Sun Young Lee ◽  
Yang Kyung Cho

Purpose: We report two cases of Acanthamoeba keratitis diagnosed by Gram staining in patients who had recently worn therapeutic, soft contact lenses and had no history of lens use for visual correction.Case summary: The first patient was initially diagnosed with suspected mixed bacterial or fungal keratitis before a final diagnosis of Acanthamoeba keratitis was confirmed by Gram staining of a corneal smear. The second patient was initially diagnosed with a persistent epithelial defect caused by an earlier lid injury inflicted by a metallic foreign body, and then with a suspected mixed infection combined with herpetic uveitis. The patient was finally diagnosed with Acanthamoeba keratitis by Gram staining of a corneal smear. Both cases were treated with polyhexamethylene biguanide and chlorhexidine.Conclusions: Therapeutic, soft contact lenses are used to enhance corneal, epithelial wound healing in conjunction with antimicrobial prophylaxis. However, application of such a lens to a diseased cornea may predispose to the development of microbial keratitis caused by microorganisms resistant to the usual, prophylactic, antimicrobial eye drops. Therapeutic, soft contact lenses are associated with a risk of Acanthamoeba keratitis; early diagnosis is important. Gram staining of a corneal smear is useful in this context. Acanthamoeba is not eradicated by empirical broad-spectrum antimicrobials.


1985 ◽  
Vol 100 (3) ◽  
pp. 396-403 ◽  
Author(s):  
M.B. Moore ◽  
J.P. McCulley ◽  
M. Luckenbach ◽  
H. Gelender ◽  
C. Newton ◽  
...  

2009 ◽  
Vol 21 (5) ◽  
pp. 46-50
Author(s):  
N. Pasechnikova ◽  
◽  
G. Drozhzhina ◽  
O. Ivanova ◽  
I. Nasinnik ◽  
...  

2016 ◽  
Vol 16 (3) ◽  
pp. 117-120 ◽  
Author(s):  
T.N. Safonova ◽  
◽  
I.A. Novikov ◽  
V.I. Boev ◽  
O.V. Gladkova ◽  
...  

2021 ◽  
pp. 548-554
Author(s):  
Nir Erdinest ◽  
Naomi London ◽  
Nadav Levinger ◽  
Yair Morad

The goal of this retrospective case series is to demonstrate the effectivity of combination low-dose atropine therapy with peripheral defocus, double concentric circle design with a center distance soft contact lenses at controlling myopia progression over 1 year of treatment. Included in this series are 3 female children aged 8–10 years with progressing myopia averaging −4.37 ± 0.88 D at the beginning of treatment. Their average annual myopic progression during the 3 years prior to therapy was 1.12 ± 0.75 D. They had not attempted any myopia control treatments prior to this therapy. The children were treated with a combination of 0.01% atropine therapy with spherical peripheral defocus daily replacement soft lenses MiSight<sup>®</sup> 1 day (Cooper Vision, Phoenix, AZ, USA). They underwent cycloplegic refraction, and a slit-lamp evaluation every 6 months which confirmed no adverse reactions or staining was present. Each of the 3 children exhibited an average of 0.25 ± 0.25 D of myopia progression at the end of 1 year of treatment. To the best of the authors’ knowledge, this is the first published study exhibiting that combining low-dose atropine and peripheral defocus soft contact lenses is effective at controlling children’s moderate to severe myopia progression during 1 year of therapy.


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