scholarly journals Myopia Control with Combination Low-Dose Atropine and Peripheral Defocus Soft Contact Lenses: A Case Series

2021 ◽  
pp. 548-554
Author(s):  
Nir Erdinest ◽  
Naomi London ◽  
Nadav Levinger ◽  
Yair Morad
Keyword(s):  
Low Dose ◽  
Contact Lenses ◽  
Case Series ◽  
Concentric Circle ◽  
Retrospective Case ◽  
Soft Contact ◽  
Myopia Progression ◽  
Soft Contact Lenses ◽  
Center Distance ◽  
Myopia Control

The goal of this retrospective case series is to demonstrate the effectivity of combination low-dose atropine therapy with peripheral defocus, double concentric circle design with a center distance soft contact lenses at controlling myopia progression over 1 year of treatment. Included in this series are 3 female children aged 8–10 years with progressing myopia averaging −4.37 ± 0.88 D at the beginning of treatment. Their average annual myopic progression during the 3 years prior to therapy was 1.12 ± 0.75 D. They had not attempted any myopia control treatments prior to this therapy. The children were treated with a combination of 0.01% atropine therapy with spherical peripheral defocus daily replacement soft lenses MiSight<sup>®</sup> 1 day (Cooper Vision, Phoenix, AZ, USA). They underwent cycloplegic refraction, and a slit-lamp evaluation every 6 months which confirmed no adverse reactions or staining was present. Each of the 3 children exhibited an average of 0.25 ± 0.25 D of myopia progression at the end of 1 year of treatment. To the best of the authors’ knowledge, this is the first published study exhibiting that combining low-dose atropine and peripheral defocus soft contact lenses is effective at controlling children’s moderate to severe myopia progression during 1 year of therapy.

Myopiekontrolle: aktuelle Strategien

2021 ◽  
Vol 1 (5) ◽  
pp. 148-155
Keyword(s):  
Contact Lenses ◽  
Long Term Effects ◽  
Soft Contact ◽  
Myopia Progression ◽  
Soft Contact Lenses ◽  
Slowing Down ◽  
The Future ◽  
Progressive Myopia ◽  
The Individual ◽  
Myopia Control

Purpose. The prevalence of myopia is increasing worldwide and its long-term effects can have major impacts on eye health. Paediatric onset of myopia leads to a higher risk for developing high levels of myopia in adulthood. Slowing down or stopping myopia progression is an important task for the future. Material and Methods. Based on a literature review, the latest developments in the field of myopia control for children were summarized. The current study situation for orthokeratology, soft contact lenses, atropine therapy and spectacle lenses for the management of myopia is discussed in detail. Results. Results on the safety and effectiveness of orthokeratology and modified soft contact lenses are exceedingly consistent. Soft multifocal contact lenses, as well as newer spectacle lenses, recently received regulatory approval for myopia control. Studies on the administration of atropine recommend a dosage of 0.01 - 0.05 %. All methods slow down myopia progression and decrease axial length growth of the eye. Side effects, adverse events or discontinuation of treatment only occur in the rarest of cases. Orthokeratology and atropine continue to deliver the best results. Conclusion. From today’s perspective, carrying out myopia control can be recommended with great certainty. The choice of method depends on the individual requirements of each patient, with all methods offering success in reducing myopia progression. In the future, even more advanced contact lens geometries, more precise atropine dosages or improved optics of spectacle lenses will further increase the success of the treatment. Keywords. Progressive myopia, myopia control, children, contact lenses, atropine, spectacle lenses

scholarly journals Treatment of Rapid Progression of Myopia: Case Series and Literature Review

2021 ◽  
pp. 875-881
Author(s):  
Nir Erdinest ◽  
Naomi London ◽  
Nadav Levinger ◽  
Itay Lavy ◽  
Eran Pras ◽  
...  
Keyword(s):  
Contact Lens ◽  
Axial Length ◽  
Contact Lenses ◽  
Case Series ◽  
Rapid Progression ◽  
Retrospective Case ◽  
Soft Contact ◽  
Myopia Progression ◽  
Current Case ◽  
Soft Contact Lens

This retrospective case series demonstrates the combination of 0.05% atropine with MiSight<sup>®</sup> 1 day (Cooper vision, Sar Ramon, CA, USA) in rapid progression of myopia of 4 children. MiSight<sup>®</sup> 1 day is a peripheral defocus, center-distance soft contact lens and is effective at controlling moderate progression of myopia during the course of 1 year. The current case series included 2 females and 2 males with an average age of 9.68 ± 0.26 years and an average axial length of 24.81 ± 0.92 mm. Their myopic progression during the previous year was −1.45 ± 0.27 D. The children had not attempted any myopia control thus far. This relatively high increase prompted a combination treatment of daily instillation of 0.05% atropine and MiSight, a daily replacement soft contact lens. Cycloplegic refraction and a slit-lamp evaluation were performed every 6 months to confirm no adverse reactions or staining was present. The 8-item contact lens dry eye questionnaire (CLDEQ-8) score of these children was 10.66 ± 1.52. The average myopia progression at the end of 1 year decreased to −0.41 ± 0.11 D, and the average axial length increase was 0.28 ± 0.08 mm. To the best of the authors’ knowledge, this is the first published study showing a combination of 0.05% atropine and peripheral defocus soft contact lenses indicating efficacy at controlling moderate myopia progression.

Results of a two-year clinical study of myopia control with bifocal defocus-inducing soft contact lenses

2021 ◽  
Vol 137 (3) ◽  
pp. 5
Author(s):  
S.E. Avetisov ◽  
A.V. Myagkov ◽  
A.V. Egorova ◽  
Z.N. Poskrebysheva ◽  
O.A. Zhabina
Keyword(s):  
Clinical Study ◽  
Contact Lenses ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Myopia Control

scholarly journals The Spatial Distribution of Relative Corneal Refractive Power Shift and Axial Growth in Myopic Children: Orthokeratology Versus Multifocal Contact Lens

2021 ◽  
Vol 15 ◽  
Author(s):  
Fan Jiang ◽  
Xiaopeng Huang ◽  
Houxue Xia ◽  
Bingqi Wang ◽  
Fan Lu ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Contact Lenses ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Refractive Power ◽  
Power Shift ◽  
The Difference ◽  
Axial Growth ◽  
Corneal Refractive Power ◽  
Myopia Control

PurposeTo determine if the spatial distribution of the relative corneal refractive power shift (RCRPS) explains the retardation of axial length (AL) elongation after treatment by either orthokeratology (OK) or multifocal soft contact lenses (MFCLs).MethodsChildren (8–14 years) were enrolled in the OK (n = 35) or MFCL (n = 36) groups. RCRPS maps were derived by computing the difference between baseline and 12-month corneal topography maps and then subtracting the apex values. Values at the same radius were averaged to obtain the RCRPS profile, from which four parameters were extracted: (1) Half_x and (2) Half_y, i.e., the x- and y-coordinates where each profile first reached the half peak; (3) Sum4 and (4) Sum7, i.e., the summation of powers within a corneal area of 4- and 7-mm diameters. Correlations between AL elongation and these parameters were analyzed by multiple linear regression.ResultsAL elongation in the OK group was significantly smaller than that in the MFCL group (p = 0.040). Half_x and Half_y were also smaller in the OK group than the MFCL group (p &lt; 0.001 each). Half_x was correlated with AL elongation in the OK group (p = 0.005), but not in the MFCL group (p = 0.600). In an analysis that combined eyes of both groups, Half_x was correlated with AL elongation (β = 0.161, p &lt; 0.001).ConclusionsThe OK-induced AL elongation and associated RCRPS Half_x were smaller than for the MFCL. Contact lenses that induce RCRPS closer to the corneal center may exert better myopia control.

Accommodation Dynamics in Children Wearing Bifocal Soft Contact Lenses with High Addition Power

The Eye ◽  
2021 ◽  
Vol 23 (1) ◽  
pp. 7-14
Author(s):  
E. P. Tarutta ◽  
S. V. Milash ◽  
M. V. Epishina
Keyword(s):  
Contact Lenses ◽  
Gradual Increase ◽  
Soft Contact ◽  
Near Vision ◽  
Accommodative Response ◽  
Optical Biometry ◽  
Soft Contact Lenses ◽  
Power Increase ◽  
Full Correction ◽  
Myopia Control

Purpose: to evaluate dynamics of subjective and objective accommodation in children wearing bifocal soft contact lenses (BSCLs) for myopia control with +4.00 D addition power. M e t h o d s: the study involved 22 patients (44 eyes).Mean age amounted to 10.1  ± 1.46 years and mean myopic refraction amounted to –3.21  ± 1.23 D. Patients were fitted Prima BIO Bi-focal BSCLs (OKVision Retail, Russia). All patients underwent cycloplegic refraction assessed with Auto Ref/Keratometer ARK 530A (Nidek, Japan), had axial length measured with IOL Master 500 optical biometry device (Carl Zeiss, Germany), had positive relative accommodation (PRA) assessed with and without lenses and had binocular (BAR) and monocular (MAR) accommodative response assessed at a distance of 33 cm with WAM-5500 Binocular Accommodation Auto Ref/Keratometer (Grand Seiko, Japan) prior to wearing BSCLs as well as 3, 6 and 12 months after wearing BSCLs.Results: neither MAR nor BAR measured without lenses changed after 3, 6 and 12 months of wearing BSCLs (p >0,05). A change in PRA evaluated without lenses was noted after 12 months (p < 0,05). PRA evaluated with lenses after 3, 6 and 12 months differed from baseline significantly (p < 0,001). Over 12 months of wearing BSCLs, changes in AL (0.09 ± 0.17 mm) and cycloplegic refraction (0.3 ±0.43 D) correlated with baseline BAR and MAR loosely. C o n c l u s i o n: objective accommodation (MAR and BAR) did not change in the course of wearing BSCLs with +4.00 D addition power. Increase in PRA evaluated without BSCLs may be associated with improvement of accommodation due to a full correction in the optic zone. The gradual increase in PRA evaluated with BSCLs probably indicates an adaptation of patients to addition zone in near vision conditions.

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