Simulation of harmonic shear waves in the human brain and comparison with measurements from magnetic resonance elastography

2021 ◽  
Vol 118 ◽  
pp. 104449
Author(s):  
Yang Li ◽  
Ruth Okamoto ◽  
Andrew Badachhape ◽  
Chengwei Wu ◽  
Philip Bayly ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Human Brain ◽  
Shear Waves ◽  
Magnetic Resonance Elastography ◽  
Harmonic Shear

scholarly journals Lorentz force induced shear waves for magnetic resonance elastography applications

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Guillaume Flé ◽  
Guillaume Gilbert ◽  
Pol Grasland-Mongrain ◽  
Guy Cloutier
Keyword(s):  
Magnetic Resonance ◽  
Shear Wave ◽  
Lorentz Force ◽  
Wave Attenuation ◽  
Shear Waves ◽  
Estimation Method ◽  
Biological Tissues ◽  
Magnetic Resonance Elastography ◽  
Motion Generation ◽  
Wave Source

AbstractQuantitative mechanical properties of biological tissues can be mapped using the shear wave elastography technique. This technology has demonstrated a great potential in various organs but shows a limit due to wave attenuation in biological tissues. An option to overcome the inherent loss in shear wave magnitude along the propagation pathway may be to stimulate tissues closer to regions of interest using alternative motion generation techniques. The present study investigated the feasibility of generating shear waves by applying a Lorentz force directly to tissue mimicking samples for magnetic resonance elastography applications. This was done by combining an electrical current with the strong magnetic field of a clinical MRI scanner. The Local Frequency Estimation method was used to assess the real value of the shear modulus of tested phantoms from Lorentz force induced motion. Finite elements modeling of reported experiments showed a consistent behavior but featured wavelengths larger than measured ones. Results suggest the feasibility of a magnetic resonance elastography technique based on the Lorentz force to produce an shear wave source.

scholarly journals Magnetic resonance elastography of the human brain using a multiphase DENSE acquisition

2019 ◽  
Vol 81 (6) ◽  
pp. 3578-3587 ◽  
Author(s):  
Johannes Strasser ◽  
Michaela Tanja Haindl ◽  
Rudolf Stollberger ◽  
Franz Fazekas ◽  
Stefan Ropele
Keyword(s):  
Magnetic Resonance ◽  
Human Brain ◽  
Magnetic Resonance Elastography

High-resolution mechanical imaging of the human brain by three-dimensional multifrequency magnetic resonance elastography at 7T

NeuroImage ◽  
2014 ◽  
Vol 90 ◽  
pp. 308-314 ◽  
Author(s):  
Jürgen Braun ◽  
Jing Guo ◽  
Ralf Lützkendorf ◽  
Jörg Stadler ◽  
Sebastian Papazoglou ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
High Resolution ◽  
Human Brain ◽  
Three Dimensional ◽  
Magnetic Resonance Elastography ◽  
Mechanical Imaging

scholarly journals Magnetic resonance elastography of slow and fast shear waves illuminates differences in shear and tensile moduli in anisotropic tissue

2016 ◽  
Vol 49 (7) ◽  
pp. 1042-1049 ◽  
Author(s):  
J.L. Schmidt ◽  
D.J. Tweten ◽  
A.N. Benegal ◽  
C.H. Walker ◽  
T.E. Portnoi ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Shear Waves ◽  
Magnetic Resonance Elastography

FE Modeling of Living Human Brain Using Multifrequency Magnetic Resonance Elastography

2011 ◽  
Vol 66-68 ◽  
pp. 384-389 ◽  
Author(s):  
Hamed Ajabi Naeeni ◽  
Mohammad Haghpanahi
Keyword(s):  
Magnetic Resonance ◽  
Human Brain ◽  
Loss Modulus ◽  
Viscoelastic Behavior ◽  
Magnetic Resonance Elastography ◽  
Fe Model ◽  
Mr Elastography ◽  
Internal Organs ◽  
Effective Technique

Viscoelasticity is an inherent property of the soft biological tissue and is increasingly used as a diagnostic parameter, e.g. in characterizing Brain disease, liver fibrosis and breast tumors or tissue-mimicking phantoms preparation. MR elastography (MRE) enables the noninvasive determination of the viscoelastic behavior of human internal organs. In this study, multifrequency magnetic resonance elastography was used to investigate and validate the numerical simulation of human brain viscoelasticity generated by ABAQUS. The dynamic behavior of storage modulus (G') and loss modulus (G") obtained by MRE at different frequency ranges were used to generate viscoelastic FE model of brain tissue. Then, shear modulus (µ) and shear viscosity (η) were compared to experimental data. MRE validate the finite element as an effective technique for measurement of rheological material properties. Results indicate the capability of FEM to simulation and comparison of experimental results.

Optimization of a Multifrequency Magnetic Resonance Elastography Protocol for the Human Brain

2019 ◽  
Author(s):  
Mehmet Kurt ◽  
Lyndia Wu ◽  
Kaveh Laksari ◽  
Efe Ozkaya ◽  
Zeynep M. Suar ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Human Brain ◽  
Magnetic Resonance Elastography
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