FE Modeling of Living Human Brain Using Multifrequency Magnetic Resonance Elastography

2011 ◽  
Vol 66-68 ◽  
pp. 384-389 ◽  
Author(s):  
Hamed Ajabi Naeeni ◽  
Mohammad Haghpanahi
Keyword(s):  
Magnetic Resonance ◽  
Human Brain ◽  
Loss Modulus ◽  
Viscoelastic Behavior ◽  
Magnetic Resonance Elastography ◽  
Fe Model ◽  
Mr Elastography ◽  
Internal Organs ◽  
Effective Technique

Viscoelasticity is an inherent property of the soft biological tissue and is increasingly used as a diagnostic parameter, e.g. in characterizing Brain disease, liver fibrosis and breast tumors or tissue-mimicking phantoms preparation. MR elastography (MRE) enables the noninvasive determination of the viscoelastic behavior of human internal organs. In this study, multifrequency magnetic resonance elastography was used to investigate and validate the numerical simulation of human brain viscoelasticity generated by ABAQUS. The dynamic behavior of storage modulus (G') and loss modulus (G") obtained by MRE at different frequency ranges were used to generate viscoelastic FE model of brain tissue. Then, shear modulus (µ) and shear viscosity (η) were compared to experimental data. MRE validate the finite element as an effective technique for measurement of rheological material properties. Results indicate the capability of FEM to simulation and comparison of experimental results.

scholarly journals Magnetic resonance elastography of the human brain using a multiphase DENSE acquisition

2019 ◽  
Vol 81 (6) ◽  
pp. 3578-3587 ◽  
Author(s):  
Johannes Strasser ◽  
Michaela Tanja Haindl ◽  
Rudolf Stollberger ◽  
Franz Fazekas ◽  
Stefan Ropele
Keyword(s):  
Magnetic Resonance ◽  
Human Brain ◽  
Magnetic Resonance Elastography

High-resolution mechanical imaging of the human brain by three-dimensional multifrequency magnetic resonance elastography at 7T

NeuroImage ◽  
2014 ◽  
Vol 90 ◽  
pp. 308-314 ◽  
Author(s):  
Jürgen Braun ◽  
Jing Guo ◽  
Ralf Lützkendorf ◽  
Jörg Stadler ◽  
Sebastian Papazoglou ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
High Resolution ◽  
Human Brain ◽  
Three Dimensional ◽  
Magnetic Resonance Elastography ◽  
Mechanical Imaging

Determination of In-Vivo Elastic Properties of Soft Tissue Using Magnetic Resonance Elastography

2003 ◽  
Author(s):  
Francis E. Kennedy ◽  
Marvin M. Doyley ◽  
Elijah E. W. Van Houten ◽  
John B. Weaver ◽  
Keith D. Paulsen
Keyword(s):  
Magnetic Resonance ◽  
Soft Tissue ◽  
Elastic Properties ◽  
Magnetic Resonance Elastography ◽  
Tissue Properties ◽  
In Vivo Measurement ◽  
Ultrasonic Methods ◽  
Accurate Quantification

In-vivo measurement of the elastic properties of soft tissue have been made using a variety of direct techniques, such as indentation probes and rotary shear actuators, but they are unable to access much of the soft tissue of interest. Indirect ultrasonic methods for imaging elastic properties of soft tissue were first introduced about 15 years ago, see Ophir (1991). Although the results of ultrasonic elastography studies have been quite promising, they may not be suited for applications requiring accurate quantification of soft tissue properties. An alternative to ultrasound, magnetic resonance imaging, has the advantage of enabling precise measurement of all three components of tissue displacement. The reconstruction of elastic properties from the imaged displacement field is called magnetic resonance elastography (MRE), and is the subject of this paper.

scholarly journals Modeling and Simulation of Head Trauma Utilizing White Matter Properties from Magnetic Resonance Elastography

Modelling ◽  
2020 ◽  
Vol 1 (2) ◽  
pp. 225-241
Author(s):  
Amit Madhukar ◽  
Martin Ostoja-Starzewski
Keyword(s):  
White Matter ◽  
Magnetic Resonance ◽  
Shear Wave ◽  
Mechanical Response ◽  
Material Model ◽  
Magnetic Resonance Elastography ◽  
Head Model ◽  
Fe Model ◽  
Inversion Algorithm ◽  
Hyper Elastic

Tissues of the brain, especially white matter, are extremely heterogeneous—with constitutive responses varying spatially. In this paper, we implement a high-resolution Finite Element (FE) head model where heterogeneities of white matter structures are introduced through Magnetic Resonance Elastography (MRE) experiments. Displacement of white matter under shear wave excitation is captured and the material properties determined through an inversion algorithm are incorporated in the FE model via a two-term Ogden hyper-elastic material model. This approach is found to improve model predictions when compared to experimental results. In the first place, mechanical response in the cerebrum near stiff structures such as the corpus callosum and corona radiata are markedly different compared with a homogenized material model. Additionally, the heterogeneities introduce additional attenuation of the shear wave due to wave scattering within the cerebrum.

In Vivo Determination of Hepatic Stiffness Using Steady-State Free Precession Magnetic Resonance Elastography

2006 ◽  
Vol 41 (12) ◽  
pp. 841-848 ◽  
Author(s):  
Dieter Klatt ◽  
Patrick Asbach ◽  
Jens Rump ◽  
Sebastian Papazoglou ◽  
Rajan Somasundaram ◽  
...  
Keyword(s):  
Steady State ◽  
Magnetic Resonance ◽  
Steady State Free Precession ◽  
Magnetic Resonance Elastography ◽  
Free Precession
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