The Efficacy of Negative Pressure Wound Therapy as a Singular Modality to Accelerate Wound Healing for Limb Salvage: A Case Report

Objective: Mechanical negative pressure wound therapy is an ultraportable, light weight and disposable single-use device that has been shown to promote wound healing. This study evaluated home use of a mechanically powered negative pressure wound therapy (NPWT) in diabetic foot wounds. Methods: Patients underwent revascularisation and/or debridement or amputation before starting mechanical NPWT. Wound outcomes and images of the wounds were recorded at each follow-up visit by the wound nurse. Patients were followed up until wound closure or end of therapy. Results: A total of 12 patients (each with one wound) were included in the study. Of the 12 wounds, 33.3% (n=4) of wounds achieved primary wound closure while the remaining 66.6% (n=8) of wounds demonstrated a mean wound size reduction of 37.5±0.13%. Of the closed wounds, mean time to healing was 4.75±2.50 weeks. There was 100% limb salvage with no further debridement or amputations, and no 30-day unplanned readmissions. Mean length of hospital stay before starting home NPWT was 9.75±6.31 days. Mean number of NPWT changes was 8.33±2.67 sessions, while mean duration of therapy was 4.0±1.54 weeks. Mean cost of home NWPT therapy was US$1904±731 per patient. Conclusion: The home use of mechanically powered NPWT in diabetic foot wounds demonstrated excellent wound healing rates and 100% limb salvage, with no complications.

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Single-use NPWT device with telemedical wound monitoring in the treatment of acne inversa in apregnant patient – case report

Negative Pressure Wound Therapy Journal ◽

10.18487/npwtj.v6i2.51 ◽

2019 ◽

Vol 6 (2) ◽

pp. 4-6

Author(s):

Kinga Zastawna ◽

Alicja Żalejko-Strychalska ◽

Tomasz Banasiewicz

Keyword(s):

Wound Healing ◽

Case Report ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Outpatient Setting ◽

Acne Inversa ◽

Patient Case ◽

Wound Therapy ◽

Single Use

Acne inversa (AI) is a chronic inflammatory skindisease significantly impacting the patient’s quality of life.Management guidelines for acne inversa during pregnancy donot exist. We decided to use a single-use negative pressurewound therapy (PICO, Smith & Nephew) while managing apregnant patient with AI. Negative pressure wound therapy(NPWT) seemed to improve the patient’s condition, managingthe exudation, reducing edema, and improving local regeneration,as well as epithelialization. The method was also absolutelysafe for the fetus and feasible to conduct in the outpatientdepartment - what was of utmost importance for the patient.The telemedical monitoring of wound healing using mobiletechnologies seems to be gaining importance for patients andmedical practitioners. In the described case, we used the iWound(Polmedi, Poland) application in an outpatient setting.

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The use of negative pressure wound therapy (NPWT), as an adjunct for primary wound healing, in deep partial-thickness paediatric foot burns: A case report

Burns Open ◽

10.1016/j.burnso.2020.03.002 ◽

2020 ◽

Vol 4 (2) ◽

pp. 60-63

Author(s):

Howard Chu ◽

Mohamed Maklad ◽

Tom Cobley ◽

Sankhya Sen

Keyword(s):

Wound Healing ◽

Case Report ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Wound Therapy ◽

Partial Thickness

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Early results of negative pressure wound therapy in treatment of chronic wounds

QJM ◽

10.1093/qjmed/hcaa050.069 ◽

2020 ◽

Vol 113 (Supplement_1) ◽

Author(s):

S A Maaty ◽

S M Gerges ◽

A A El-desoki ◽

M M Khalil

Keyword(s):

Wound Healing ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Chronic Wounds ◽

Armed Forces ◽

Wound Therapy ◽

Wound Debridement ◽

Accelerate Wound Healing ◽

Early Results ◽

Stimulation Of

Abstract Background Chronic wounds may affect only the epidermis and dermis, or they may affect tissues all the way to the fascia. Chronic wounds seem to be detained in one or more of the phases of wound healing. For example, chronic wounds often remain in the inflammatory stage for too long. Aim of the work to assess the effect of negative pressure wound therapy in management of chronic wound. Patients and Methods This is prospective study was conducted on 30 Egyptian volunteers participated; they were 20 males and 10 females, between the age of 18 and 70 years. This study was conducted from July 2017 to July 2018 at Ain shams university specialized hospitals and Alexandria armed forces hospital. Results VAC therapy, together with periodical surgical wound debridement and specific antibiotic therapy, could be helpful to promote and accelerate wound healing of foot lesions after restoration of an adequate distal blood flow through surgical revascularization or angioplasty. Conclusion Negative-pressure wound therapy (NPWT) devices are designed to apply controlled suction to a wound bed at continuous or intermittent pressure settings to stimulate wound closure. Negative pressure can result in numerous alterations in the wound environment, including removal of excess exudate containing high concentrations of proteases and inflammatory cytokines, stimulation of senescent cells, mobilization of macrophages, and stimulation of angiogenesis.

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Optimizing microenvironment by integrating negative pressure and exogenous electric fields via a flexible porous conductive dressing to accelerate wound healing

Biomaterials Science ◽

10.1039/d0bm01172j ◽

2021 ◽

Vol 9 (1) ◽

pp. 238-251

Author(s):

Ying Chen ◽

Yi Liang ◽

Jie Liu ◽

Jinrui Yang ◽

Naixin Jia ◽

...

Keyword(s):

Wound Healing ◽

Electric Field ◽

Polyurethane Foam ◽

Electric Fields ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Pig Model ◽

Wound Therapy ◽

Accelerate Wound Healing ◽

Ag Nanowire

Integrated directional exogenous electric field and negative pressure wound therapy via Ag nanowire polyurethane foam dressing to accelerate wound healing in pig model.

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Experience of negative pressure wound therapy over sternal wound healing: A retrospective review

WCET Journal ◽

10.33235/wcet.39.2.9-18 ◽

2019 ◽

Vol 39 (2) ◽

pp. 9-18

Author(s):

Wai Sze Ho ◽

Wai Kuen Lee ◽

Ka Kay Chan ◽

Choi Ching Fong

Keyword(s):

Wound Healing ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Assessment Tool ◽

Wound Care ◽

Wound Therapy ◽

Treatment Pathways ◽

Wound Assessment ◽

One Year

Objectives The aim of this study was to retrospectively review the effectiveness of negative pressure wound therapy (NPWT) in sternal wound healing with the use of the validated Bates-Jensen Wound Assessment Tool (BWAT), and explore the role of NPWT over sternal wounds and future treatment pathways. Methods Data was gathered from patients' medical records and the institution's database clinical management system. Seventeen subjects, who had undergone cardiothoracic surgeries and subsequently consulted the wound care team in one year were reviewed. Fourteen of them were included in the analysis. Healing improvement of each sternal wound under continuous NPWT and continuous conventional dressings was studied. In total, 23 continuous NPWT and 13 conventional dressing episodes were analysed with the BWAT. Results Among conventional dressing episodes, sternal wound improvement was 2.5–3% over 10 days to 3.5 weeks, whereas 4–5% sternal healing was achieved in 5 days to 2 weeks with sternal wire presence. Better healing at 11% in 1 week by conventional dressing was attained after sternal wire removal. In NPWT episodes, 8–29%, 13–24%, and 15–46% of healing was observed in 2 weeks, 3.5 to 5 weeks and 6 to 7 weeks, respectively. Only 39% wound healing was acquired at the 13th week of NPWT in one subject. With sternal wire present, 6%–29% wound healing progress was achieved by NPWT in 1–4 weeks, and 16–23% wound improvement in 2 to 4.5 weeks by NWPT after further surgical debridement. After sternal wire removal, 6–34% sternal wound healing occurred by continuous NPWT for 1–2 weeks, and maximum healing at 46% after 2.5 weeks of NPWT were observed. Conclusions Better wound healing was achieved in the NPWT group in comparison to conventional dressings alone. However, suboptimal sternal wound healing by NPWT alone was observed. Removal of sternal wire may improve the effectiveness of NPWT. Successful tertiary closure after NPWT among subjects supports the important bridging role of NPWT in sternal wound healing. Factors causing stagnant sternal wound healing by NPWT alone are discussed.

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The effects and use of negative pressure wound therapy – a set of case reports

Perspectives in Surgery ◽

10.33699/pis.2020.99.4.183-188 ◽

2020 ◽

Vol 99 (4) ◽

pp. 183-188

Keyword(s):

Wound Healing ◽

High Risk ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Chronic Wounds ◽

Wide Spectrum ◽

Case Reports ◽

Modern Medicine ◽

Wound Therapy ◽

Basic Set

Modern medicine offers a wide spectrum of wound healing resources for acute or chronic wounds. Negative pressure wound therapy (NPWT) is a very effective method, allowing complicated defects and wounds to heal. The basic set is usually provided with various special accessories to facilitate the use and support safe application of NPWT to high-risk tissue. Selected case reports are presented herein to document the special use and combinations of materials in negative pressure wound therapy.

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