Recovery from severe frontotemporal dysfunction at 3years after N-methyl-d-aspartic acid (NMDA) receptor antibody encephalitis

2013 ◽  
Vol 20 (4) ◽  
pp. 611-613 ◽  
Author(s):  
Frank Leypoldt ◽  
Mathias Gelderblom ◽  
Daniel Schöttle ◽  
Sascha Hoffmann ◽  
Klaus-Peter Wandinger
Keyword(s):  
Nmda Receptor ◽  
Aspartic Acid ◽  
Receptor Antibody

Decreased N-methyl-d-aspartic acid (NMDA) receptor levels are associated with mercury exposure in wild and captive mink

2007 ◽  
Vol 28 (3) ◽  
pp. 587-593 ◽  
Author(s):  
Niladri Basu ◽  
Anton M. Scheuhammer ◽  
Kirsti Rouvinen-Watt ◽  
Nicole Grochowina ◽  
R. Douglas Evans ◽  
...  
Keyword(s):  
Nmda Receptor ◽  
Aspartic Acid ◽  
Mercury Exposure

Opioids modulate N-methyl-D-aspartic acid (NMDA)-evoked responses of trigeminothalamic neurons

1996 ◽  
Vol 76 (3) ◽  
pp. 2093-2096 ◽  
Author(s):  
X. M. Wang ◽  
S. S. Mokha
Keyword(s):  
Nmda Receptor ◽  
Dorsal Horn ◽  
Aspartic Acid ◽  
Opioid Receptor ◽  
Receptor Agonist ◽  
Receptor Activation ◽  
Evoked Responses ◽  
Nociceptive Neurons ◽  
Nociceptive Transmission ◽  
Opioid Receptor Agonist

1. The present study investigated opioid-mediated modulation of N-methyl-D-aspartic acid (NMDA)-evoked responses of trigeminothalamic neurons in the superficial and deeper dorsal horn of the medulla (trigeminal nucleus caudalis) in rats anesthetized with urethane. 2. Microiontophoretic application of NMDA activated 18/19 trigeminothalamic neurons. Administration of [D-Ala2, N-Me-Phe4,Gly5-ol]-Enkephalin, a selective mu-opioid receptor agonist, reduced the NMDA-evoked responses in 77% of trigeminothalamic neurons. [D-Pen2,5]-Enkephalin, a selective delta-opioid receptor agonist, produced inhibition of NMDA-evoked responses in 36% of neurons. 3. We suggest that 1) NMDA-receptor activation excites trigeminothalamic nociceptive neurons and may, therefore, mediate nociceptive transmission in the medullary dorsal horn; and 2) the predominantly inhibitory modulation of NMDA-receptor-mediated responses of nociceptive trigeminothalamic neurons by activation of mu- and delta-opioid receptors may provide a neural mechanism for the antinociceptive actions of opioids.

scholarly journals Ion channels in EEG: isolating channel dysfunction in NMDA receptor antibody encephalitis

Brain ◽  
2018 ◽  
Vol 141 (6) ◽  
pp. 1691-1702 ◽  
Author(s):  
Mkael Symmonds ◽  
Catherine H Moran ◽  
M Isabel Leite ◽  
Camilla Buckley ◽  
Sarosh R Irani ◽  
...  
Keyword(s):  
Ion Channels ◽  
Nmda Receptor ◽  
Receptor Antibody

scholarly journals Anti-NMDA-receptor antibody detected in encephalitis, schizophrenia, and narcolepsy with psychotic features

2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Ko Tsutsui ◽  
Takashi Kanbayashi ◽  
Keiko Tanaka ◽  
Shuken Boku ◽  
Wakako Ito ◽  
...  
Keyword(s):  
Nmda Receptor ◽  
Receptor Antibody ◽  
Psychotic Features

scholarly journals Anti-NMDA-receptor antibody encephalitis in infants

2015 ◽  
Vol 4 ◽  
pp. 99-101 ◽  
Author(s):  
Amr A. Matoq ◽  
Adam S. Rappoport ◽  
Yiting Yang ◽  
Jessica O'Babatunde ◽  
Rubina Bakerywala ◽  
...  
Keyword(s):  
Nmda Receptor ◽  
Receptor Antibody

scholarly journals NMDA receptor antibody encephalitis presenting with enhancing lesion and seizures

2017 ◽  
Vol 7 (5) ◽  
pp. 433-435 ◽  
Author(s):  
Michael H. Rosenbloom ◽  
Melissa K. Samuelsson ◽  
Michael E. Brogan ◽  
Teresa A. Tran-Lim
Keyword(s):  
Nmda Receptor ◽  
Receptor Antibody
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