Relationship of Weight Outcomes, Co-Occurring Conditions, and Severity of Autism Spectrum Disorder in the Study to Explore Early Development

Abstract Caring for children with disabilities contributes to increased levels of parent stress or caregiver strain. However, the potential relationship of sensory features to strain among caregivers of children with autism spectrum disorder (ASD) and other developmental disabilities (DD) is unknown. Sensory features include overreactions, underreactions, and unusual interests in sensations, which may negatively impact family functioning. This descriptive study confirmed three caregiver strain types (i.e., objective, subjective internalized, subjective externalized) and explored differences among ASD (n = 71) and DD (n = 36) groups, with the ASD group reporting higher levels. Furthermore, this study explored the contribution of sensory features to caregiver strain, finding differential contributions to strain in the ASD group and covariate contributions (i.e., child cognition, mother's education) in the DD group.

Download Full-text

The microbiota promotes social behavior by neuro-immune modulation of neurite complexity

10.1101/2020.05.01.071373 ◽

2020 ◽

Author(s):

Joseph J. Bruckner ◽

Sarah J. Stednitz ◽

Max Z. Grice ◽

Johannes Larsch ◽

Alexandra Tallafuss ◽

...

Keyword(s):

Autism Spectrum Disorder ◽

Social Behavior ◽

Recent Work ◽

Early Development ◽

Neurodevelopmental Disorders ◽

Immune Modulation ◽

Autism Spectrum ◽

Spectrum Disorder ◽

Developmental Programs ◽

Developmental Mechanisms

AbstractHost-associated microbiotas normally guide the trajectory of intrinsically encoded developmental programs, and dysbiosis is linked to neurodevelopmental disorders such as autism spectrum disorder. Recent work suggests that microbiotas modulate social phenotypes associated with these disorders, though developmental mechanisms linking microbiotas to social behavior are not well understood. We discovered that the zebrafish microbiota is required for normal social behavior. Using this model to examine neuronal features modulated by the microbiota during early development, we found that the microbiota restrains neurite complexity and targeting of specific forebrain neurons required for normal social behavior. The microbiota is also required for normal forebrain infiltration of microglia, the brain’s resident phagocytes that remodel neuronal arbors, suggesting the microbiota modulates arborization via a neuro-immune route. Our work establishes a foundation for study of microbial and host mechanisms that link the microbiota and social behavior in an experimentally tractable model vertebrate.

Download Full-text

PENGARUH POLA ASUH ORANG TUA DAN DIET BEBAS GLUTEN/KASEIN TERHADAP PERBAIKAN GEJALA AUTISM SPECTRUM DISORDER (ASD)

Al-Hikmah ◽

10.24260/al-hikmah.v13i1.1348 ◽

2019 ◽

Vol 13 (1) ◽

pp. 169

Author(s):

Sari Eka Pratiwi ◽

Fitri Sukmawati

Keyword(s):

Autism Spectrum Disorder ◽

Parenting Style ◽

Gastrointestinal Symptoms ◽

Complementary Therapy ◽

Development Stage ◽

Autism Spectrum ◽

Spectrum Disorder ◽

Nutrition Intervention ◽

Gluten Free ◽

Relationship Of

Autism Spectrum Disorder (ASD) is a development impairment characterized by cognitive and neurobehavioral deficit, including communication and social problem that need psycology and education intervention for the children and the parents, also nutrition intervention with Gluten-Free Casein-Free (GFCF). This study’s aim is to identify the parenting style and Gluten-Free Casein-Free diet role in ASD’s symptoms modification. This study was start with collecting the references and research publications, and study the relationship of parenting style and GFCF diet to ASD. Flexible Parenting style in ASD is important and need to be adjusted based on the characteristic, development stage and the children’s situation. Diet GFCF can be a complementary therapy to reduce ASD’s symptoms particularly children with gluten allergy and have celiac disease. However, the children without any gastrointestinal symptoms to gluten/casein products need a consideration and advance examination to determine GFCF diet requirement. [Autism Spectrum Disorder (ASD) merupakan suatu kelainan perkembangan saraf yang dicirikan dengan adanya defisit kognitif dan neurobehavioralyang mencakup masalah komunikasi dan perilaku sosial, yang memerlukanintervensi psikologis dan edukasi pada anak dan orang tua, serta intervensi nutrisi dengan pembatasan asupan gluten dan kasein yang dikenal dengan diet Gluten-Free Casein-Free (GFCF). Penulisan telaah jurnal ini bertujuan untuk mengetahui pengaruh pola asuh orang tua dan pembatasan asupan gluten dan kasein terhadap perbaikan gejala ASD. Penulisan telaah literatur dilakukan dengan mengumpulkan berbagai sumber teori dan hasil penelitian kemudian dilakukan telaah terhadap hubungan kedua faktor yaitu pola asuh dan pembatasan asupan gluten dan kasein terhadap ASD. Gaya pengasuhan pada ASD perlu dilakukan secara fleksibel sesuai dengan keunikan karakter anak, tahap perkembangan anak, dan situasi yang sedang dihadapi. Terapi pembatasan asupan gluten/kasein dapat menjadi pilihan terapi pelengkap untuk mengurangi gejala ASD terutama pada anak yang alergi gluten dan mengalami penyakit celiac. Namun, pada anak yang tidak memiliki gejala saluran cerna terhadap produk gluten/kasein perlu pertimbangan dan pemeriksaan lebih lanjut untuk menentukan perlu tidaknya pembatasan gluten/kasein pada makanannya]. Kata Kunci: Autism Spectrum Disorder (ASD), Gluten-Free Casein-Free (GFCF), Pola Asuh Pada ASD, Autisme, Terapi Nutrisi Autism Spectrum Disorder (ASD).

Download Full-text