Development of torsadogenic risk assessment using human induced pluripotent stem cell-derived cardiomyocytes: Japan iPS Cardiac Safety Assessment (JiCSA) update

Cardiac Safety ◽

Proarrhythmia Risk Assessment in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Using the Maestro MEA Platform

Toxicological Sciences ◽

10.1093/toxsci/kfv128 ◽

2015 ◽

Vol 147 (1) ◽

pp. 286-295 ◽

Cited By ~ 55

Author(s):

Yusheng Qu ◽

Hugo M. Vargas

Keyword(s):

Risk Assessment ◽

Stem Cell ◽

Pluripotent Stem Cell ◽

Cardiac safety pharmacology: from human ether-a-gogo related gene channel block towards induced pluripotent stem cell based disease models

Expert Opinion on Drug Safety ◽

10.1517/14740338.2012.639358 ◽

2011 ◽

Vol 11 (2) ◽

pp. 285-298 ◽

Cited By ~ 27

Author(s):

Udo Kraushaar ◽

Thomas Meyer ◽

Dietmar Hess ◽

Lior Gepstein ◽

Christine L Mummery ◽

...

Keyword(s):

Stem Cell ◽

Pluripotent Stem Cell ◽

Disease Models ◽

Channel Block ◽

Related Gene ◽

Cardiac Safety ◽

Safety Pharmacology ◽

Predicting cardiac safety using human induced pluripotent stem cell-derived cardiomyocytes combined with multi-electrode array (MEA) technology: A conference report

Journal of Pharmacological and Toxicological Methods ◽

10.1016/j.vascn.2018.01.003 ◽

2018 ◽

Vol 91 ◽

pp. 36-42 ◽

Cited By ~ 11

Author(s):

Petra Mulder ◽

Tessa de Korte ◽

Elena Dragicevic ◽

Udo Kraushaar ◽

Richard Printemps ◽

...

Keyword(s):

Stem Cell ◽

Pluripotent Stem Cell ◽

Electrode Array ◽

Conference Report ◽

Cardiac Safety ◽

Induced Pluripotent ◽

Multi Electrode Array

Resolving the reversed rate effect of calcium channel blockers on human induced pluripotent stem cell-derived cardiomyocytes and the impact on in vitro cardiac safety evaluation

Journal of Pharmacological and Toxicological Methods ◽

10.1016/j.vascn.2019.05.158 ◽

2019 ◽

Vol 99 ◽

pp. 106595 ◽

Cited By ~ 1

Author(s):

Haoyu Zeng ◽

Jixin Wang ◽

Holly Clouse ◽

Armando Lagrutta ◽

Frederick Sannajust

Keyword(s):

Stem Cell ◽

Calcium Channel Blockers ◽

Pluripotent Stem Cell ◽

Safety Evaluation ◽

Channel Blockers ◽

Cardiac Safety ◽

Induced Pluripotent ◽

The Impact

Resolving the Reversed Rate Effect of Calcium Channel Blockers on Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes and the Impact on In Vitro Cardiac Safety Evaluation

Toxicological Sciences ◽

10.1093/toxsci/kfy264 ◽

2018 ◽

Vol 167 (2) ◽

pp. 573-580 ◽

Cited By ~ 8

Author(s):

Haoyu Zeng ◽

Jixin Wang ◽

Holly Clouse ◽

Armando Lagrutta ◽

Frederick Sannajust

Keyword(s):

Stem Cell ◽

Calcium Channel Blockers ◽

Pluripotent Stem Cell ◽

Safety Evaluation ◽

Channel Blockers ◽

Cardiac Safety ◽

Induced Pluripotent ◽

The Impact

Toxicity testing in the era of induced pluripotent stem cells: A perspective regarding the use of patient-specific induced pluripotent stem cell–derived cardiomyocytes for cardiac safety evaluation

Current Opinion in Toxicology ◽

10.1016/j.cotox.2020.04.001 ◽

2020 ◽

Vol 23-24 ◽

pp. 50-55 ◽

Cited By ~ 2

Author(s):

Li Pang

Keyword(s):

Stem Cells ◽

Stem Cell ◽

Pluripotent Stem Cells ◽

Pluripotent Stem Cell ◽

Safety Evaluation ◽

Toxicity Testing ◽

Patient Specific ◽

Cardiac Safety ◽

Comparative analysis of media effects on human induced pluripotent stem cell-derived cardiomyocytes in proarrhythmia risk assessment

Journal of Pharmacological and Toxicological Methods ◽

10.1016/j.vascn.2017.11.002 ◽

2018 ◽

Vol 90 ◽

pp. 39-47 ◽

Cited By ~ 15

Author(s):

Derek Schocken ◽

Jayna Stohlman ◽

Jose Vicente ◽

Dulciana Chan ◽

Dakshesh Patel ◽

...

Keyword(s):

Risk Assessment ◽

Stem Cell ◽

Comparative Analysis ◽

Media Effects ◽

Pluripotent Stem Cell ◽

Effect of natural killer cells on induced pluripotent stem cell-derived bioartificial cardiac tissue

The Thoracic and Cardiovascular Surgeon ◽

10.1055/s-0034-1367266 ◽

2014 ◽

Vol 62 (S 01) ◽

Author(s):

G. Kensah ◽

H. Baraki ◽

S. Saito ◽

J. Dahlmann ◽

D. Skvorc ◽

...

Keyword(s):

Stem Cell ◽

Natural Killer Cells ◽

Natural Killer ◽

Pluripotent Stem Cell ◽

Cardiac Tissue ◽

Killer Cells ◽

Use of 3D culture systems to generate human induced pluripotent stem cell-derived [beta]-cells in vitro

Endocrine Abstracts ◽

10.1530/endoabs.57.003 ◽

2018 ◽

Author(s):

Fantuzzi Federica ◽

Toivonen Sanna ◽

Schiavo Andrea Alex ◽

Pachera Nathalie ◽

Rajaei Bahareh ◽

...

Keyword(s):

Stem Cell ◽

Beta Cells ◽

Pluripotent Stem Cell ◽

3D Culture ◽

Culture Systems ◽

Cellular modeling of citrin deficiency using human induced pluripotent stem cell-derived hepatocytes

Reproduction Abstracts ◽

10.1530/repabs.3.p036 ◽

2016 ◽

Author(s):

Yong-Mahn Han ◽

Yeji Kim ◽

Beom-Hee Lee ◽

Han-Wook Yoo

Keyword(s):

Stem Cell ◽

Pluripotent Stem Cell ◽

Cellular Modeling ◽

Induced Pluripotent ◽

Citrin Deficiency